DAIC

JANUARY 12, 2024

a commercial-stage biopharmaceutical company focused on genetic diseases and cancers, announced that positive results from its Phase 3 ATTRibute-CM study of acoramidis for patients with ATTR-CM were published in the New England Journal of Medicine (NEJM). milla1cf Fri, 01/12/2024 - 13:23 January 12, 2024 — BridgeBio Pharma, Inc. ,

Cardiomyopathy 105

Cardiomyopathy Medicare Cancer Hospital 105

Dr. Paddy Barrett

JANUARY 16, 2024

Cardiovascular disease, cancer and dementia account for 60% of all deaths in the US. Let’s start with Cancer. Compared to those who had ‘Low’ lifestyle scores, those with ‘Ideal’ scores were 27% less likely to be diagnosed with cancer in the next ten years. The leading causes of death are clear.

Cancer 94

Cancer Dementia Diabetes Cardiovascular Disease 94

Dr. Paddy Barrett

DECEMBER 12, 2023

There is even emerging evidence that the use of such therapies may even reduce the risk of colorectal cancer by up to 50% 6. Low levels of muscle mass are associated with a range of adverse outcomes, and a therapy that causes this would not be a good long-term health strategy. 2023 Aug 10;389(6):514-526. 2023 Nov 11.

Obesity 105

Obesity Heart Attack Heart attacks Diet 105

Dr. Paddy Barrett

AUGUST 23, 2024

While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. A higher daily step count is also linked to significantly lower cancer, stroke and heart disease rates.

Exercise 116

Exercise Dementia Cancer Chronic Disease 116

Dr. Paddy Barrett

APRIL 26, 2024

They are dying less often from the two leading causes of death: Cardiovascular Disease and Cancer. To the point that those with 6 to 7 of the healthy factors in place had essentially eliminated the increased risk of dying from cardiovascular disease or cancer compared to those without type 2 diabetes. For sure. ( They set the odds.

Heart Disease 105

Heart Disease Coronary Artery Disease Diabetes Genetic predisposition 105

Frontiers in Cardiovascular Medicine

OCTOBER 7, 2024

BackgroundPrimary pericardial mesothelioma (PMPM) is a rare, aggressive, and lethal form of cancer. Due to its rarity, low incidence and poor prognosis, PMPM has no accepted standard-of-care treatment options with management and outcomes often extrapolated from diffuse pleural mesothelioma.

Chest Pain 52

Chest Pain Ultrasound Cancer Outcomes 52

DAIC

MAY 8, 2024

The earlier and longer the treatment was delivered, the better the outcomes. If inflammation is successfully controlled, diseases – such as arthritis, pulmonary hypertension, Crohn's disease, inflammatory bowel diseases, diabetes, cancer and autoimmune diseases – can be treated more effectively.

Ultrasound 115

Ultrasound Pulmonary Research Hypertension 115

Dr. Paddy Barrett

APRIL 12, 2024

Similar patterns have been observed for cardiovascular disease and also cancer. Even 30 minutes per day has been shown to improve health outcomes 6. 2023 Apr;7(4):e313-e328. Over a 10-year time frame, compared to 4000 steps, taking 7000 steps every day resulted in a 51% reduction in all-cause mortality. More movement.

Quality of Life 125

Quality of Life Blood Pressure Exercise Chronic Disease 125

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. The complications of the procedure and patient’s outcomes were discussed.MethodsWe identified two patients who were admitted to our medical center between January 2022 to December 2022 for subclavian‐carotid artery bypass procedure.

Outcomes 40

Outcomes Chest Pain Coronary Artery Disease Aortic 40

Journal of Cardiovascular Pharmacology

JULY 31, 2023

ICIs have significantly improved cancer survival in several advanced malignancies and there are currently over 90 different cancer indications for ICIs. Also, high doses of corticosteroids may adversely impact cancer outcomes. Also, high doses of corticosteroids may adversely impact cancer outcomes.

Cancer 40

Cancer Pharmacology Outcomes Article 40

DAIC

FEBRUARY 29, 2024

This year’s theme, “Advancing Cardiovascular Care for All” brings the latest practice-changing breakthroughs, along with top experts debating and discussing outcomes of highly-anticipated clinical trials. 24 from April 6 - 8, 2024 in Atlanta, GA at the Georgia World Congress Center. The Guidelines Sessions at ACC.24 12:15 p.m.

Aortic valve 103

Aortic valve Myocardial Infarction Aortic Blood Pressure 103

Dr. Anish Koka

MAY 16, 2023

Soviet biologist Trofim Lysenko famously rejected the objective reality of Mendelian genetics because it clashed with the Marxist philosophy that the environment, not genetics, was the primary determinant of outcomes. But what should matter is outcomes not diagnoses. Subscribe for free to receive new posts and support my work.

Chest Pain 52

Chest Pain Coronary Artery Disease Cancer Heart attacks 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. Several risk factors can contribute to the development of cerebral venous sinus thrombosis including hypercoagulable states, dehydration, infections, head or neck injuries, cancer, and some rheumatological diseases (1).

Thrombosis 40

Thrombosis Outcomes Cancer Risk Factors 40

Dr. Smith's ECG Blog

SEPTEMBER 25, 2024

Nevertheless, cases like the one presented today — illustrate the continued need for review of these points that are KEY to attaining a good outcome. For more on use of Opiates with acute ischemic CP — See the January 6, 2023 post in Dr. Smith's ECG Blog ). Review of the CASE: Dr. Smith has reviewed today's case in step-by-step detail.

Chest Pain 120

Chest Pain Blog Hospital Tachycardia 120

Dr. Paddy Barrett

MAY 17, 2024

Regardless of what is driving the effect, it is clear that experiencing high levels of stress is associated with worse outcomes. Receiving a cancer diagnosis is associated with a more than five-fold increased risk of a cardiovascular event 5. While studies attempt to correct for these influences, it can be very hard to do.

Heart Disease 101

Heart Disease Heart attacks Heart Attack Risk Factors 101

Dr. Smith's ECG Blog

APRIL 21, 2023

ECGs labeled ‘normal’ Initially the patient had been on the medical wards for cancer treatment, and had been noted to have on/off chest pain with a troponin I that was mildly elevated around the 300 ng/L range. The reason for this patient's admission to the hospital the day before was for cancer treatment.

Chest Pain 52

Chest Pain STEMI Cancer Hemorrhage 52

Dr. Malcolm Kendrick

JANUARY 30, 2023

31st January 2023 With the resignation of Jacinda Ardern, my thoughts were dragged back to Covid once more. The only outcome that really matters. The graph itself begins in January 2017 and finishes in January 2023. On the BBC, a man with cancer was being interviewed. Others with cancer will not be getting treatment.

COVID-19 52

COVID-19 Article Nursing Cancer 52

Dr. Paddy Barrett

NOVEMBER 14, 2023

Let’s start with the simple fact that a lot of cancer diagnoses are simply down to ‘bad luck’ You can do everything right and still get cancer. Cancer - Less so. If exercise reduces all-cause mortality, it seems safe to say that it is reducing cardiovascular and cancer deaths.

Cancer 52

Cancer Exercise Obesity Cardiovascular Disease 52

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Published Research kschukar Thu, 04/20/2023 - 11:12 Recently published (2016 – present) manuscripts utilizing STS data: Adult Cardiac Surgery, General Thoracic Surgery, Congenital Heart Surgery, and Intermacs/Pedimacs.

Research 52

Research Coronary Artery Bypass Graft Aortic valve Congenital 52

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Published Research kschukar Thu, 04/20/2023 - 11:12 Recently published (2016 – present) manuscripts utilizing STS data: Adult Cardiac Surgery, General Thoracic Surgery, Congenital Heart Surgery, and Intermacs/Pedimacs.

Research 52

Research Coronary Artery Bypass Graft Aortic valve Congenital 52

DAIC

MARCH 8, 2024

The FDA decision is based on the results of the landmark SELECT phase 3 cardiovascular outcomes trial that examined the effect of adding Wegovy 2.4 1,2 The primary composite outcome occurred in 6.5% 1,2 The primary composite outcome occurred in 6.5% These may be symptoms of thyroid cancer. 2 Wegovy 2.4 with placebo.

Obesity 111

Obesity Heart Disease Heart attacks Heart Attack 111

Dr. Paddy Barrett

OCTOBER 24, 2023

Share Why you die earlier is likely down to the earlier onset of the two major diseases that are the leading causes of death worldwide: Cardiovascular Disease Cancer. A diagnosis of diabetes in your 30s is associated with about a FOUR TIMES higher risk of both cardiovascular and cancer mortality. 2023 Oct;11(10):731-742.

Diabetes 52

Diabetes Cancer Exercise Cardiovascular Disease 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. 0.48, p=0.001), CNS cancer (OR: 0.24, 95% CI: 0.06‐0.93, 0.93, p=0.039), other types of cancer (OR: 0.47, 95% CI: 0.32‐0.69, CVT and other diagnoses, and EVT and other procedures, were identified using standard ICD 10 codes.

Thrombosis 40

Thrombosis Cancer Inpatient Hospital 40

Dr. Malcolm Kendrick

OCTOBER 30, 2024

Such support is provided by a number of government institutions and charities, including the Medical Research Council, National Institute for Health and Care Research, Department of Health and Social Care, British Heart Foundation, Cancer Research UK and Wellcome. I don’t think so. I have read some utter bollocks in my life.

Cholesterol 145

Cholesterol Article Research Diet 145