Stroke Journal

FEBRUARY 1, 2024

Stroke, Ahead of Print. Cervical artery dissection is an important cause of stroke, particularly in young adults. In patients with acute ischemic stroke attributable to cervical artery dissection, acute treatment strategies such as thrombolysis and mechanical thrombectomy are reasonable in otherwise eligible patients.

Genetic predisposition 75

Genetic predisposition Outcomes Thrombolysis Congenital 75

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP23-ATMP23, February 1, 2024. Background:Studies have reported longer emergency department (ED) wait times and delayed stroke treatment for Black versus White patients. Minority patients also have severe stroke symptoms compared to White patients.

Strokes 40

Strokes Stroke Thrombolysis Hospital 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionImportance:Tenecteplase (TNK) use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke (AIS), given its ease of use with results from randomized trials showing non‐ inferiority and comparable safety to Alteplase (tPA).

Hemorrhage 40

Hemorrhage Thrombolysis Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP44-ATMP44, February 1, 2025. Introduction:Understanding factors that contribute to missed diagnoses of acute ischemic stroke (AIS) may improve diagnostic accuracy. treatment window for thrombolysis. treatment window for thrombolysis. window (60% vs 40%, p<0.01).

Strokes 40

Strokes Stroke Thrombolysis Education 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A144-A144, February 1, 2024. Introduction:CTP has increasingly been incorporated into the evaluation of all patients with suspected acute ischemic stroke (AIS), including those with minor symptoms. years (IQR 54-73) and 56% were women. 73% were Black or African American, 20% White, and 4% Asian.

Thrombolysis 40

Thrombolysis Strokes Stroke Academic 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP104-ATP104, February 1, 2024. Introduction:Accurate outcome prognostication in acute ischemic stroke (AIS) informs essential medical decision-making for clinicians, patients, and families. Cases with a modified Rankin scale (mRS) of 0-2 at 90 days (i.e.

Thrombolysis 40

Thrombolysis Strokes Stroke Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP66-ATP66, February 1, 2024. Introduction:Alteplase was the first approved tissue plasminogen activator and standard of care for acute ischemic stroke (AIS). Patients prior to November 2022 received Alteplase, and those after November 2022 received Tenecteplase. Alteplase vs 53.09

Strokes 40

Strokes Stroke Academic Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP108-ATP108, February 1, 2024. Introduction:The Alberta Stroke Program Early CT Score (ASPECTS) is often used in considering whether patients are appropriate for thrombolysis and/or thrombectomy after acute ischemic stroke (AIS).

Strokes 40

Strokes Stroke Thrombolysis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP53-AWMP53, February 1, 2025. Background:Treatment options and outcomes in stroke also depends on pre-hospital delays. Compared to the patients who reached by non-EMS mode, patients who reached by EMS mode were more likely to receive intravenous thrombolysis (16% vs 44%,).

Hospital 40

Hospital Strokes Stroke Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A34-A34, February 1, 2024. A change in the stroke alert process (January 2023) focused on early notification of stroke alert, CT and telestroke. After changing the ED stroke process, there was a reduction in DTN of 29.26

Strokes 40

Strokes Stroke Thrombolysis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP165-AWP165, February 1, 2025. This is especially critical for wake-up strokes where emergent brain magnetic resonance imaging (eMRI-brain) is included in the evaluation process. It is important to note that stroke onset may have influenced the presence of DWI-FLAIR mismatch.

Strokes 40

Strokes Stroke Thrombolysis Academic 40

Stroke: Vascular and Interventional Neurology

AUGUST 21, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue 6 , November 1, 2023. middle cerebral artery occlusions), first‐pass effect (modified Thrombolysis in Cerebral Infarction score≥2B) was achieved in 90/166 (54.2%) successfully revascularized patients. female, 89.2% female, 89.2%

Strokes 40

Strokes Stroke Thrombolysis Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP43-ADP43, February 1, 2025. Objective:Most patients with concern for an acute stroke are transported by Emergency Medical Services (EMS) or a Mobile Stroke Unit (MSU) from community hospitals to a Comprehensive Stroke Center (CSC).

Strokes 40

Strokes Stroke Thrombolysis Academic 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A78-A78, February 1, 2024. 1–3Mobile Stroke Units (MSUs) bring diagnostic and treatment tools for AIS directly to patients, achieving faster thrombolytic administration and better outcomes.4,5Objective:This Per capita income did not differ.

Strokes 40

Strokes Stroke Thrombolysis Education 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP86-ATMP86, February 1, 2024. Introduction:Tenecteplase improves reperfusion and functional outcomes in stroke patients with large vessel occlusion. Use of TPA was converted to TNK on 1/11/2022 per hospital policy. Secondary outcomes were NIHSS at 24 hours and at discharge. versus 7.0,

Thrombolysis 40

Thrombolysis Strokes Stroke Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP172-ATP172, February 1, 2025. hours of last known well time follow the code stroke algorithm predicated on BEFAST symptoms. If photo is consistent with an RAO, thrombolysis is offered.Results:From July 2022 to June 2024, 1079 fundus photos were obtained across 10 stroke centers.

Strokes 40

Strokes Stroke Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP43-ATP43, February 1, 2024. Background:Stroke centers following AHA guidelines for the treatment of acute ischemic stroke, are challenged by compliance with documentation of vital sign, neuro and neurovascular assessments post thrombolysis interventions.

Document 40

Document Nursing Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP78-AWMP78, February 1, 2024. Introduction:Mobile stroke units (MSUs) are an evolving means to expedited acute stroke management.

Hemorrhage 40

Hemorrhage Blood Pressure Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP146-AWP146, February 1, 2024. Introduction:Intravenous thrombolytic therapy remains the cornerstone of management in acute ischemic stroke (AIS) patients.

ICU 40

ICU Critical Care Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A24-A24, February 1, 2024. Introduction:Tenecteplase (TNK) has arisen as an alternative to alteplase (ALT) for emergent treatment of acute ischemic stroke. The exposure was treatment with TNK vs ALT. The primary endpoints were DTN and DIDO.

Strokes 40

Strokes Stroke Thrombolysis Hospital 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe mantra ‘time is brain’ cannot be overstated for patients suffering from acute ischemic stroke. DIDO was defined as the time between spoke hospital door in arrival and door out exit.

Strokes 40

Strokes Stroke Thrombolysis Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP126-AWP126, February 1, 2024. Methods:Data for this study were obtained from the Get with the Guidelines Stroke database. Methods:Data for this study were obtained from the Get with the Guidelines Stroke database.

Strokes 40

Strokes Stroke Outcomes Technology 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP10-AWP10, February 1, 2024. Introduction:While observational data suggest that dexmedetomidine may have neuroprotective effects on ischemic brain, its clinical use in acute ischemic stroke is limited due to concerns about cerebral vasoconstriction. vs. 28.8%; p=0.24).

Strokes 40

Strokes Stroke Outcomes Thrombolysis 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 28, 2023

Stroke: Vascular and Interventional Neurology, Ahead of Print. BACKGROUNDIn patients with acute ischemic stroke secondary to large vessel occlusion, achieving modified Thrombolysis in Cerebral Infarction (mTICI) 2c/3 (excellent recanalization) over mTICI 2b is associated with improved functional outcomes.

Strokes 40

Strokes Stroke Thrombolysis Diabetes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP192-AWP192, February 1, 2024. Introduction:Despite comparable outcomes for different frontline techniques in mechanical thrombectomy (MT) for acute ischemic stroke (AIS), there are sparse data regarding if and when to switch techniques if the first pass is unsuccessful.

Circulation 40

Circulation Strokes Stroke Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP191-AWP191, February 1, 2024. Introduction:The mantra ‘time is brain’ cannot be overstated for patients suffering from acute ischemic stroke. The median NIHSS was 16 (10-20), 50% were treated with intravenous thrombolysis at a spoke, and TICI 2B-3 reperfusion was achieved in 87% at the hub.

Strokes 40

Strokes Stroke Thrombolysis Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP205-AWP205, February 1, 2024. The aim of this study is to develop and validate a stroke prediction tool for outcome in MT for AIS patients with low ASPECTS using data from an ongoing international multicenter registry, the Stroke Thrombectomy and Aneurysm Registry (STAR).Methods:236

Strokes 40

Strokes Stroke Circulation Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP193-ATP193, February 1, 2024. Successful recanalization was defined as modified Thrombolysis in Cerebral Ischemia Score≥ 2b. The primary outcome was a 90-day modified Rankin Scale (mRS) of 0-3.

Outcomes 40

Outcomes Strokes Stroke Hemorrhage 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 21, 2023

Stroke: Vascular and Interventional Neurology, Ahead of Print. BACKGROUNDAs the number of thrombectomy passes increases during endovascular therapy (EVT) for acute stroke, neurointerventionalists must weigh the risks of potential complications against the risk of failing to recanalize the affected vessel.

Outcomes 40

Outcomes Strokes Stroke Hemorrhage 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 17, 2023

Stroke: Vascular and Interventional Neurology, Ahead of Print. male, median age 75 (interquartile range 65–82) years, and median National Institutes of Health Stroke Scale score 8 (5–12). male, median age 75 (interquartile range 65–82) years, and median National Institutes of Health Stroke Scale score 8 (5–12).

Stents 40

Stents Stent Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP212-ATP212, February 1, 2024. Background:Endovascular thrombectomy (EVT) for treatment of acute ischemic stroke (AIS) in the proximal cerebrovasculature has, since its inception, become part of the standard of care when addressing AIS. The study was approved by the local IRB.

Outcomes 40

Outcomes Strokes Stroke Thrombolysis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP211-ATP211, February 1, 2024. Introduction:The extended Thrombolysis in Cerebral Infarction (eTICI) scale has been demonstrated to correlate strongly with clinical outcomes.

Thrombolysis 40

Thrombolysis Strokes Stroke Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A127-A127, February 1, 2025. Secondary outcome evaluated symptomatic intracranial hemorrhage (sICH) post thrombolysis comparing APP versus neurology residents using Fishers exact test. Patients treated greater than 4.5 95% CI -11.43,16.44], p=0.72.Conclusion:The

Academic 40

Academic Thrombolysis Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A85-A85, February 1, 2024. Intravenous thrombolysis was administered in 55 patients (22.1%) while general anesthesia was used in 94/248 patients (37.9%). years [SD 11.7], 208 [83.5%] male) were included. The median baseline NIHSS score was 23 (IQR 12-30) and median PC-ASPECTS was 9 (IQR 7-10).

Circulation 40

Circulation Outcomes Thrombolysis Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP127-ATP127, February 1, 2024. Background/Purpose:Distal medium vessel occlusions (DMVOs) account for a large percentage of vessel occlusions resulting in acute ischemic stroke (AIS) with disabling symptoms. years old [mean+-SD], 35 female). for optimal sensitivity (71% [52.0-85.8%])

Outcomes 40

Outcomes Thrombolysis Biomarkers Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThrombolysis with recombinant tissue plasminogen activator remains vital to acute ischemic stroke (AIS) therapy. The admission National Institutes of Health Stroke Scale scores (NIHSS) were similar. A p‐value of <0.05

Thrombolysis 40

Thrombolysis Pharmacology Strokes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP132-AWP132, February 1, 2024. Introduction:In patients with acute ischemic stroke, FLAIR vascular hyperintensity (FVH) is a reliable indicator of large vessel occlusion and salvageable tissue requiring mechanical thrombectomy (MT).

Thrombolysis 40

Thrombolysis Outcomes Strokes Stroke 40