Open Heart

MAY 17, 2022

Objectives The management of severe aortic stenosis mandates consideration of aortic valve intervention for symptomatic patients. However, for asymptomatic patients with severe aortic stenosis, recent randomised trials supported earlier intervention. to 0.96; I 2 15%). to 0.56; I 2 77%).

Stenosis 40

Stenosis Aortic Aortic valve Heart Failure 40

DAIC

FEBRUARY 3, 2025

2022 Aug, 80 (9) 934946 Kronenberg F. et al, Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement , European Heart Journal, Volume 43, Issue 39, 14 October 2022, Pages 39253946 Koschinsky ML et al.

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Journal of the American Heart Association

FEBRUARY 3, 2025

However, the prognostic value of malnutrition status in patients with moderatetosevere aortic stenosis is unclear. ConclusionsIn patients with moderate or severe aortic stenosis, we found that high CONUT scores, low nutritional risk index scores, and low prognostic nutritional index scores were associated with allcause death.

Stenosis 40

Stenosis Aortic Aortic valve Academic 40

Ken Grauer, MD

FEBRUARY 3, 2024

BUT — Cardiac catheterization done a little later did not reveal any significant stenosis. Despite the absence of significant coronary stenosis on her post-arrest cath — the ECG in Figure-1 is clearly diagnostic of an extensive anterolateral STEMI ( presumably from acute LAD [ L eft A nterior D escending ] coronary artery occlusion).

Blog 164

Blog Cardiac Arrest STEMI Plaque 164

Dr. Smith's ECG Blog

APRIL 22, 2024

Despite description of Wellens’ Syndrome over 40 years ago — this syndrome remains misunderstood by all-to-many clinicians ( See My Comment at the bottom of the page in the August 12, 2022 post in Dr. Smith’s ECG Blog ). Angiography : --Culprit for the patient's unstable angina/Wellen syndrome is a ruptured plaque in the mid LAD. --As

Chest Pain 118

Chest Pain Myocardial Infarction Anatomy Angina 118

DAIC

APRIL 23, 2024

Aortic stenosis is a common heart problem typically caused by a narrowing of the heart’s aortic valve due to excessive calcium deposited on the valve leaflets. Eur J Cardiothorac Surg 2022 Aug 3;62(3) 10 Klautz RJM, Rao V, Reardon MJ, et al. August 2022;62(3):ezac374. 11Sohn SH, Kang Y, Kim JS, et al.,

Aortic valve 111

Aortic valve Aortic Innovation Cardiothoracic 111

DAIC

JUNE 13, 2024

Aortic stenosis is a common heart problem typically caused by a narrowing of the heart’s aortic valve due to excessive calcium deposited on the valve leaflets. Eur J Cardiothorac Surg 2022 Aug 3;62(3) 10 Klautz RJM, Rao V, Reardon MJ, et al. August 2022;62(3):ezac374. 11Sohn SH, Kang Y, Kim JS, et al.,

Aortic valve 109

Aortic valve Aortic Innovation Cardiothoracic 109

Circulation

OCTOBER 23, 2024

BACKGROUND:This study aimed to compare the incidence and prognostic implications of new-onset conduction disturbances after surgical aortic valve replacement (SAVR) in patients with bicuspid aortic valve (BAV) aortic stenosis (AS) versus patients with tricuspid aortic valve (TAV) AS (ie, BAV-AS and TAV-AS, respectively).

Aortic valve 40

Aortic valve Bicuspid/Mitral Aortic Tricuspid 40

Stroke Journal

JANUARY 30, 2025

Background:Intracranial artery stenosis (ICAS) is a progressive pathological process. Stroke, Volume 56, Issue Suppl_1 , Page ATP274-ATP274, February 1, 2025. All patients received follow-ups through August 2023.

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Stenosis Hospital Blood Pressure Strokes 40

DAIC

JUNE 7, 2024

The CoreValve and next-generation Evolut TAVR systems are used in TAVR procedures for patients with symptomatic severe aortic stenosis (AS), which are less invasive and typically result in a quicker recovery time than open heart surgery.i The natural history and rate of progression of aortic stenosis. iii Am Heart Assoc. 120.018816.

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TAVR Aortic valve Aortic Stenosis 111

Circulation: Cardiovascular Interventions

OCTOBER 17, 2023

BACKGROUND:Data concerning the outcomes of transcatheter aortic valve replacement in type 0 bicuspid aortic stenosis (AS) are scarce.

Aortic valve 40

Aortic valve Bicuspid/Mitral Aortic Tricuspid 40

Frontiers in Cardiovascular Medicine

FEBRUARY 21, 2024

Materials and methods This retrospective, institutional-review board approved study included consecutive patients with calcified coronary artery plaques undergoing CCTA with PCD-CT and invasive coronary angiography between July and December 2022. Virtual monoenergetic images (VMI) and VNCa images were reconstructed. 68, ICC: 94 and 1%, p  = .07,

Plaque 69

Plaque Stenosis 69

DAIC

FEBRUARY 13, 2024

Coronary CTA With AI-QCT Interpretation: Comparison With Myocardial Perfusion Imaging for Detection of Obstructive Stenosis Using Invasive Angiography as Reference Standard. AJR Am J Roentgenol 2022 Sep;219(3):407-419. Journal of Cardiovascular Computed Tomography Vol. 7 Bär S, Nabeta T, Maaniitty T.

Coronary Artery Disease 103

Coronary Artery Disease Ischemia Atherosclerosis Cardiovascular Imaging 103

DAIC

APRIL 1, 2024

Cholesterol may cause or exacerbate some types of valvular heart disease, so drug companies are testing statins and PSK9 inhibitors (which lower cholesterol even more than statins) against aortic stenosis.

Technology 105

Technology Heart Disease Innovation Ultrasound 105

Open Heart

SEPTEMBER 18, 2024

Methods We retrospectively analysed data from 745 consecutive patients who underwent TAVI for severe aortic stenosis from November 2013 to July 2022. To seek the predictors and clinical impacts of PPMI and investigate the recovery rate from conduction disorders. Results Postoperative PPMI was performed in 7.1% (53/745) of patients.

Aortic valve 52

Aortic valve Pacemaker Aortic Heart Failure 52

Journal of the American Heart Association

FEBRUARY 26, 2025

Percentage of stenosis was 50% (IQR, 36%58%). mm (IQR, 7.59.5) (P<0.001), with median stenosis expansion at 103% (IQR, 51%146%). ConclusionsOptimusL stents can safely treat arterial and venous stenosis in infants and small children via a lowprofile approach with good outcomes. male) with median age and weight of 3.4

Stents 45

Stents Stent Stenosis Congenital 45

Stroke Journal

FEBRUARY 1, 2024

However, it has not been clinically investigated in patients with asymptomatic CASO.Methods:A cross-sectional observational study was conducted between January 2017 and March 2022.

Stenosis 40

Stenosis Risk Factors Circulation Strokes 40

DAIC

JUNE 19, 2024

Research is also underway into algorithms for the diagnosis of Aortic Stenosis and Myocarditis and should be ready for commercialization in the next 18 – 36 months. In April 2022 BMS had received FDA approval for Camzyos, the first drug developed specifically for targeting HCM. How Has Funding Progressed?

AFIB 105

AFIB Reimbursement Research Atrial Fibrillation 105

Stroke Journal

JANUARY 30, 2025

This study aimed to determine the current prevalence of CAS and examine the associated gender differences in adults.Methods:From September 2021 to June 2022, we established a prospective cohort to study CAS and cardiovascular disease across 25 project sites in Henan, China, utilizing a multistage whole-population sampling method.

Atherosclerosis 40

Atherosclerosis Plaque Stenosis Cardiovascular Disease 40

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

Even in patients whose moderate stenosis undergoes thrombosis, most angiograms show greater than 50% stenosis after the event. However, one can certainly imagine that many thromboses of non-obstructive lesions completely lyse and do not leave a stenosis on same day or next day angiogram.

Coronary Angiogram 109

Coronary Angiogram Plaque Thrombosis STEMI 109

Frontiers in Cardiovascular Medicine

DECEMBER 12, 2024

33 preoperative clinical features and 4 postoperative complications were collected in each group. LASSO is a regression analysis method that performs both variable selection and regularization to enhance model prediction accuracy and interpretability.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Strokes Stroke Aortic 52

Stroke Journal

FEBRUARY 1, 2024

Unless there is a hemodynamically significant stenosis, neuroradiology reports tend to be rarely descriptive of these features.Methods:In our previous study published in September 2022, we analyzed a patient sample drawn from the stroke registry of the HFHS between June 2016 and June 2021.

Plaque 40

Plaque Stenosis Embolism Strokes 40

Heart BMJ

DECEMBER 15, 2023

Transcatheter aortic valve implantation (TAVI) is a minimally invasive surgical procedure that has revolutionised the treatment of severe aortic stenosis (AS). However, the presence of PH in patients undergoing TAVI has been identified as a critical factor that can influence clinical outcomes, both in the short and long terms.

Aortic valve 40

Aortic valve Pulmonary Aortic Quality of Life 40

Circulation

NOVEMBER 11, 2024

The study took place between October 2019 and December 2022. In addition, CAVI has a statistically significant increase in severe stenosis (≥75%) and multivessel coronary artery disease. In chronic CAD, CAVI is higher in severe stenosis and multivessel coronary artery disease. CAVI in the CVD events group (9.77±1.06)

Coronary Artery Disease 40

Coronary Artery Disease Cardiovascular Disease Stenosis Blood Pressure 40

Coronary Artery Disease Journal

JUNE 13, 2024

We reviewed English case reports of cardiac cephalalgia from 1982 to 2022 using PubMed ([link] Results A 69-year-old man presented with a sudden headache without triggers or typical symptoms. Coronary computed tomography angiography (CTA) showed diffuse stenosis in the left anterior descending and the first diagonal branch arteries.

Myocardial Infarction 40

Myocardial Infarction Chest Pain Coronary Artery Disease Electrocardiogram 40

The British Journal of Cardiology

AUGUST 1, 2024

Genome-wide association and Mendelian randomisation studies have identified lipoprotein(a) (Lp[a]) as an emerging risk factor for calcific aortic stenosis and a causal risk factor for atherosclerotic cardiovascular disease (ASCVD) in different ethnicities. HEART UK recommends Lp(a) measurement in specific ‘at-risk’ cohorts.

Risk Factors 40

Risk Factors Atherosclerosis Laboratory Stenosis 40

Stroke Journal

FEBRUARY 1, 2024

Patients were included if they met VERiTAS criteria (≥50% vertebrobasilar stenosis). The DHV sign was defined as positive when the increased intensity in the basilar artery distal to stenosis was higher than the surrounding CSF signal. The DHV sign was evaluated by blinded vascular neurologists and neuro-radiologists.

Circulation 40

Circulation Outcomes Stenosis Strokes 40

Dr. Smith's ECG Blog

JULY 21, 2024

Angiography : LMCA — 90-99% osteal stenosis. LCx — 50-69% stenosis of the 1st marginal branch; with 100% distal LCx occlusion. Cath findings shown above in Dr. Nossen's discussion confirm multi-vessel disease , including 90-99% osteal stenosis of the LMCA. The image shows the impella device in place.

Arrhythmia 131

Arrhythmia Cardiogenic Shock Bradycardia Defibrillator 131

Dr. Smith's ECG Blog

OCTOBER 30, 2023

The first hs troponin I returned at 1100 ng/L Angiogram Lesion on 1st Obtuse Marginal : Proximal subsection = 90% stenosis Stented. [link] Case continued The cath lab was activated rapidly. DBT was 120 minutes, pretty good for a Non-STEMI OMI. Pre procedure TIMI III flow was noted. Post Procedure TIMI III flow was present.

STEMI 123

STEMI Heart Failure Stents Stent 123

Dr. Smith's ECG Blog

OCTOBER 15, 2024

It should be treated as such unless there is more information such as old or serial EKGs that can confirm a benign diagnosis, as BTWI patterns can mimic the South Africa Flag Sign (Compare this EKG to case 4 here: [link] com/2022/05/quiz-post-which- of-these-if-any-are-omi.html ). Patient 1 remained in the hospital overnight.

Chest Pain 116

Chest Pain STEMI Echocardiogram Stents 116

Dr. S. Venkatesan MD

SEPTEMBER 23, 2024

Likelihood of truth : High The flamboyant genius of Andreas Roland Gruntzig, from Zurich gifted us the path-breaking treatment modality for coronary stenosis five decades ago. Transluminal dilatation of coronary-artery stenosis. * Caution : Language -Harsh. In whatever angle we look , ORBITA-2 looks a redundant one ( EuroIntervention.

Angina 52

Angina Academic Stenosis Article 52

Dr. Smith's ECG Blog

SEPTEMBER 29, 2024

On follow up angiography, there was a large OM1 and small AV groove Cx/LPL visible as the vessel re-canalized LAD is noted to have diffuse 50% stenosis in the proximal segment and is occluded immediately beyond a small D1 RCA is a medium-large caliber vessel and supplies a medium rPDA, medium rPLA1, and three small rPLA branches. TIMI-0 flow.

Cardiac Arrest 110

Cardiac Arrest STEMI Ischemia SCAD 110

Dr. Smith's ECG Blog

APRIL 29, 2023

As a visual aid to facilitate recognition of the ST-T wave changes characteristic of acute posterior MI — I favor the Mirror Test ( See My Comment at the bottom of the page in the September 21, 2022 post in Dr. Smith's ECG Blog ). Supplies a very large OM1.

Chest Pain 52

Chest Pain Blog Stenosis Critical Care 52

Dr. Smith's ECG Blog

DECEMBER 14, 2022

Cath at approximately 0945: "The LAD had a 90% proximal stenosis with TIMI 3 flow which corresponds to his ECG although LV function remains preserved. With nitroglycerin there is improvement in the 90% stenosis but still persistent stenosis consistent with the dynamic nature of his presentation.

Chest Pain 52

Chest Pain STEMI Blog Stenosis 52

Dr. Smith's ECG Blog

JUNE 15, 2023

Thus, this does NOT meet STEMI criteria (though, as of 2022, it is a formal "STEMI equivalent", assuming everyone agrees that this is de Winter morphology, for which there is currently no objective definition).

STEMI 98

STEMI Chest Pain Stenosis Outcomes 98

Dr. Smith's ECG Blog

NOVEMBER 30, 2022

J Electrocardiol [Internet] 2022;Available from: [link] Cardiology opinion: Takotsubo Cardiomyopathy (EF 30-35%) V Fib Cardiac arrest Prolonged QTC NSTEMI (Smith comment: is it NSTEMI or is it Takotsubo? -- these are entirely different) Moderate single-vessel CAD. Reference on Troponins: Xenogiannis I, Vemmou E, Nikolakopoulos I, et al.

Plaque 52

Plaque Chest Pain Thrombosis Stenosis 52

Circulation: Cardiovascular Interventions

OCTOBER 22, 2023

Background:Atherosclerotic cardiovascular disease (ASCVD) is highly prevalent in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). Circulation: Cardiovascular Interventions, Ahead of Print. Exposure of interest was PVD. Primary outcome was all-cause mortality.

Aortic valve 40

Aortic valve Aortic TAVR Outcomes 40