2022, Risk Factors and Stenosis - Cardiovascular Update

Predictors of permanent pacemaker requirement in aortic stenosis patients undergoing self-expanding valve transcatheter aortic valve replacement using the cusp overlap technique

Frontiers in Cardiovascular Medicine

FEBRUARY 17, 2025

IntroductionSince TAVR was approved for lower-risk aortic stenosis (AS) patients, managing post-implantation conduction disturbances has become crucial, especially with self-expanding heart valves (SEV).

Pacemaker

Pacemaker Aortic Stenosis Aortic valve

Cerebral Hemodynamic Impairment and Cognitive Dysfunction in APOE4 Carriers With Asymptomatic Carotid Artery Stenosis/Occlusion

Journal of the American Heart Association

MARCH 13, 2025

BackgroundOur previous preclinical study demonstrated thatAPOE4targeted replacement mice exhibit more severe cerebral hypoperfusion and cognitive impairment thanAPOE3targeted replacement mice with carotid artery stenosis due to neurovascular dysfunction.

Stenosis

Stenosis Risk Factors Circulation

Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

DAIC

FEBRUARY 3, 2025

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. 2022 Aug, 80 (9) 934946 Kronenberg F. The development of the Tina-quant Lipoprotein (a) Gen.2

Cardiovascular Disease

Cardiovascular Disease Aortic valve Biomarkers Innovation

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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ECG Blog #415 — The Cath showed NO Occlusion!

Ken Grauer, MD

FEBRUARY 3, 2024

BUT — Cardiac catheterization done a little later did not reveal any significant stenosis. Despite the absence of significant coronary stenosis on her post-arrest cath — the ECG in Figure-1 is clearly diagnostic of an extensive anterolateral STEMI ( presumably from acute LAD [ L eft A nterior D escending ] coronary artery occlusion).

Blog

Blog Cardiac Arrest STEMI Plaque

Lipoprotein(a) measurement – how, why and in whom?

The British Journal of Cardiology

AUGUST 1, 2024

Genome-wide association and Mendelian randomisation studies have identified lipoprotein(a) (Lp[a]) as an emerging risk factor for calcific aortic stenosis and a causal risk factor for atherosclerotic cardiovascular disease (ASCVD) in different ethnicities.

Risk Factors

Risk Factors Atherosclerosis Laboratory Stenosis

Abstract TMP69: Impaired Cognitive Function and Cerebral Hemodynamics Associated With APOE4 in Asymptomatic Carotid Artery Stenosis/Occlusion

Stroke Journal

FEBRUARY 1, 2024

However, it has not been clinically investigated in patients with asymptomatic CASO.Methods:A cross-sectional observational study was conducted between January 2017 and March 2022.

Stenosis

Stenosis Risk Factors Circulation Stroke

Abstract 4147910: 22q11 Deletion Syndrome: A Potenitial Risk Factor For Left Pulmonary Artery Hypoplasia and Need For Intervention in Patients With Congeital Heart Disease

Circulation

NOVEMBER 11, 2024

Conclusion:Patients with 22q11 deletion syndrome are more likely to have reduced LPA to RPA ratio and need intervention on the LPA at the initial surgery, despite Tetralogy of Fallot (the only of the three lesions known to be associated with LPA stenosis) being over represented in the control group.

Pulmonary

Pulmonary Risk Factors Heart Disease Echocardiogram

What does the angiogram show? The Echo? The CT coronary angiogram? How do you explain this?

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

Even in patients whose moderate stenosis undergoes thrombosis, most angiograms show greater than 50% stenosis after the event. However, one can certainly imagine that many thromboses of non-obstructive lesions completely lyse and do not leave a stenosis on same day or next day angiogram.

Coronary Angiogram

Coronary Angiogram Plaque Thrombosis STEMI

American College of Cardiology ACC.24 Late-breaking Science and Guidelines Session Summary

DAIC

FEBRUARY 29, 2024

24: Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials (Session 402) Saturday, April 6 9:30 – 10:30 a.m.

Aortic valve

Aortic valve Myocardial Infarction Aortic Blood Pressure

Incidence, outcomes and predictors of bleeding after transfemoral TAVR

Cardiology Update

JANUARY 31, 2024

Transcatheter aortic valve replacement (TAVR) has emerged as the preferred treatment for older patients suffering from severe aortic valve stenosis, surpassing the annual patient count of those opting for surgical aortic valve replacement. in 2019-2022. Among 23,562 patients undergoing transfemoral TAVR, the mean age was 81.5 ± 6.7

TAVR

TAVR Aortic valve Outcomes Aortic

Abstract WP226: Perioperative Stroke and Cardiac Anomalies Associated With Posterior Cerebral Artery Stenosis in Children With Moyamoya

Stroke Journal

FEBRUARY 1, 2024

Risk factors and severity of disease progression in children with moyamoya and posterior cerebral artery (PCA) stenosis have not been well described in the literature. Previous research has shown an association between PCA stenosis and increased risk of post-operative stroke.

Stenosis

Stenosis Stroke Strokes Circulation

Association Between the Malnutrition Status and All‐Cause Mortality in Patients With Moderate and Severe Aortic Stenosis: A Prospective Cohort Study

Journal of the American Heart Association

FEBRUARY 3, 2025

However, the prognostic value of malnutrition status in patients with moderatetosevere aortic stenosis is unclear. Compared with normal nutrition, malnutrition was associated with an increased risk for allcause death (adjusted hazard ratio for mild and moderatesevere malnutrition, respectively: 2.82 [95% CI, 1.694.71;P<0.001]

Stenosis

Stenosis Aortic Aortic valve Academic

A 50-something with acute chest pain, a computer "Normal" ECG, and a HEART score of 3 (low risk)

Dr. Smith's ECG Blog

APRIL 29, 2023

A 50-something with no previous cardiac history and no risk factors presented to the ED with acute chest pain (pressure) that radiated to the left arm. An ECG was immediately recorded: Computer read: Normal ECG What do you think? There is ST depression in V1-V3. We showed that this is diagnostic of OMI (of the posterior wall).

Chest Pain

Chest Pain Blog Stenosis Critical Care

Abstract WP276: Large Artery Atherosclerosis and Young Stroke

Stroke Journal

FEBRUARY 1, 2024

Introduction:It is known that past the age of 35, the prevalence of large artery atherosclerosis (LAA) related strokes increases with a cardiovascular risk factor (CVRF) profile beginning to resemble that of elderly patients. Stroke, Volume 55, Issue Suppl_1 , Page AWP276-AWP276, February 1, 2024. vs. 38.2 ± 8.0 vs. 20.7%; 2.82 [0.9-9.0])

Atherosclerosis

Atherosclerosis Stroke Strokes Obesity

Published Research

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Adult Cardiac Surgery Database Lead Author Title Publication Date Jacob Raphael Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis The Annals of Thoracic Surgery January 2024 Joseph Sabik Multi-Arterial versus Single-Arterial Coronary Surgery: Ten Year Follow-up of One Million (..)

Research

Research Coronary Artery Bypass Graft Aortic valve Congenital

Published Research

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Institutional Coronary Artery Bypass Case Volumes and Outcomes European Journal of Heart Failure October 2023 Makoto Mori 1 Robotic Mitral Valve Repair for Degenerative Mitral Regurgitation The Annals of Thoracic Surgery August 2023 Carlos Diaz-Castrillion 2 Volume-Failure to Rescue Relationship in Acute Type A Aortic Dissections: An Analysis of The (..)

Research

Research Coronary Artery Bypass Graft Aortic valve Congenital

American Stroke Association to Honor 11 Leading Scientists at International Stroke Conference ISC 2024

DAIC

FEBRUARY 7, 2024

Meschia is a pioneer in the study of inherited risk factors for ischemic stroke and has had a longstanding commitment to providing the latest evidence for carotid revascularization as a means for stroke prevention. Meschia’s lecture, “Asymptomatic Carotid Stenosis: Current and Future Considerations,” will be presented Feb.

Stroke

Stroke Strokes Research Health Disparities

Predictors of permanent pacemaker requirement in aortic stenosis patients undergoing self-expanding valve transcatheter aortic valve replacement using the cusp overlap technique

Cerebral Hemodynamic Impairment and Cognitive Dysfunction in APOE4 Carriers With Asymptomatic Carotid Artery Stenosis/Occlusion

Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

Webinars

ECG Blog #415 — The Cath showed NO Occlusion!

Lipoprotein(a) measurement – how, why and in whom?

Abstract TMP69: Impaired Cognitive Function and Cerebral Hemodynamics Associated With APOE4 in Asymptomatic Carotid Artery Stenosis/Occlusion

Abstract 4147910: 22q11 Deletion Syndrome: A Potenitial Risk Factor For Left Pulmonary Artery Hypoplasia and Need For Intervention in Patients With Congeital Heart Disease

What does the angiogram show? The Echo? The CT coronary angiogram? How do you explain this?

American College of Cardiology ACC.24 Late-breaking Science and Guidelines Session Summary

Incidence, outcomes and predictors of bleeding after transfemoral TAVR

Abstract WP226: Perioperative Stroke and Cardiac Anomalies Associated With Posterior Cerebral Artery Stenosis in Children With Moyamoya

Association Between the Malnutrition Status and All‐Cause Mortality in Patients With Moderate and Severe Aortic Stenosis: A Prospective Cohort Study

A 50-something with acute chest pain, a computer "Normal" ECG, and a HEART score of 3 (low risk)

Abstract WP276: Large Artery Atherosclerosis and Young Stroke

Published Research

Published Research

American Stroke Association to Honor 11 Leading Scientists at International Stroke Conference ISC 2024

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