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Simultaneous pancreas-kidney (SPK) transplants are known to improve the quality of life and long-term survival of patients with insulin dependent diabetes and advanced renal disease. I have witnessed firsthand the significant benefits for patients with diabetes and kidney failure of receiving a pancreas and kidney transplant.
Dr. Hallberg passed in March of 2022 after a 5-year battle with stage IV lung cancer. As an expert on metabolic control and type 2 diabetes (T2D), Dr. Hallberg once gave a TedTalk titled Reversing Type 2 diabetes starts with ignoring the guidelines , which quickly accumulated 8.6
Neha Agarwal, PhD, Clinical Director at Cardiometabolic Health Congress , Informa Connect, recently presented significant findings at the 84th American Diabetes Association (ADA) Scientific Sessions. The Diabetes Track will feature: “Precision Medicine in Diabetes” by Jose C.
IntroductionThere is a higher prevalence of diabetes mellitus type 2 in Hispanics as compared to other ethnic groups in the United States. Diabetes is a risk factor for acute ischemic stroke and also a poor predictor of outcome for many interventional surgeries. or greater. vs. 20.5%; p = 0.048) and stenting (28.4%
This year’s theme, “Advancing Cardiovascular Care for All” brings the latest practice-changing breakthroughs, along with top experts debating and discussing outcomes of highly-anticipated clinical trials. 24 from April 6 - 8, 2024 in Atlanta, GA at the Georgia World Congress Center.
When compared with placebo, glucagon-like peptide-1 receptor agonists such as once-weekly semaglutide (semaglutide OW T2D) improve cardiovascular outcomes in people with type 2 diabetes (T2D), whereas dipeptidyl peptidase-4 inhibitors (DPP-4is) do not.
Introduction:Studies have reported racial disparities in acute stroke treatment and follow-up care in young patients which lead to less desirable outcomes for minorities. A logistic regression was used to evaluate the odds ratio of favorable functional outcomes (mRS 2) by 90 days. male, covering 57.2% BL, and 20.4% BL, and 20.4%
Background:The STRACK project aims to improve post-stroke patient management and the transition from acute to primary care thanks to improvements in patient pathways and monitoring cardiovascular risk factors: heart failure, diabetes, atrial fibrillation, dyslipidemia and hypertension.
We aimed to examine the impact of dexmedetomidine on outcomes in patients with anterior circulation large vessel occlusion (acLVO) requiring neurocritical care after endovascular therapy (EVT).Methods:We While favorable functional outcome was less frequently observed in the dexmedetomidine than in the comparator group (7.9%
Since 2022, the ACC, American Heart Association and European Society of Cardiology (ESC) all recommend LDL cholesterol goals of no more than 55 mg/dL for patients with cardiovascular disease or who are at very high risk for a heart attack or stroke and no more than 70 mg/dL for high-risk patients. in the placebo group.
However, its postoperative complications can have a significant effect on long-term patient outcomes. AUC, or area under the receiver operating characteristic curve, quantifies the ability of a model to distinguish between positive and negative outcomes.
Studies have reported racial disparities in young stroke patients and less desired outcomes of minorities. Socioeconomic status, risk factors, stroke etiology, acute interventions and short-term outcomes were accessed. Compared to White, black and Hispanic had higher rate of Diabetes, Hypertension and prior stroke (p<0.001).
Ensuring a follow-up neurology appointment within two weeks is vital to managing stroke risk factors like hypertension, diabetes, and atrial fibrillation. The first period, from July 2022 through June 2023, represents the timeframe before the opening of the transition-of-care clinic.
Written by Jesse McLaren A 75 year-old patient with diabetes and end stage renal disease was sent to the ED after dialysis for three days of nausea, vomiting, loose stool, lightheadedness and fatigue. Problem #1: As I emphasized in My Comment in the December 6, 2022 post — Not all patients with acute MI report chest pain. Khan et al.
At baseline, prevalence of comorbidities was high (hypertension 66% and 84%, hyperlipidemia 53% and 75%, coronary artery disease 18% and 31%, diabetes 25% and 38% in MarketScan and CDM, respectively). Introduction:Patients suffering from transient ischemic attack (TIA) are at high risk of ischemic stroke (IS). in MarketScan, 59.3%
BACKGROUNDIn patients with acute ischemic stroke secondary to large vessel occlusion, achieving modified Thrombolysis in Cerebral Infarction (mTICI) 2c/3 (excellent recanalization) over mTICI 2b is associated with improved functional outcomes. P=0.036), were less likely to have a history of diabetes (aOR, 0.42;P=0.050) P=0.012).
Written by Willy Frick A man in his 50s with a history of hypertension, dyslipidemia, type 2 diabetes mellitus, and prior inferior OMI status post DES to his proximal RCA 3 years prior presented to the emergency department at around 3 AM complaining of chest pain onset around 9 PM the evening prior. Stuckey, T., Zimetbaum, P. Tcheng, J.
Cardiometabolic conditions – specifically obesity, diabetes and heart disease – disproportionately affect the 60 million people in the U.S. Dr. Rodriguez presents to hundreds of practitioners of women's health on using digital tools and community intervention to improve outcomes in underserved ethnic populations. Register Now
In the United States, syphilis rates have been increasing at an alarming rate since 2000, and between 2018-2022 cases increased by nearly 80%. Future work is needed to examine if enhanced syphilis screening practices in acute stroke hospitalizations can be used to inform stroke management and improve patient outcomes.
Background:Mortality doubles in stroke patients when Diabetes Mellitus (DM) is present. Participating Get With The Guidelines® (GWTG)-Stroke hospitals track EBG data to improve outcomes. 21, 2022, from 51 Wisconsin Coverdell Stroke hospitals. TT2DM initiative has10 EBG data elements related to stroke and the DM subpopulation.
Patients with missed strokes were more likely female than those with accurate strokes (57% vs 39%, p<0.01), have a history of diabetes (43% vs 26%, p=0.03), and were more likely to receive recommendation for seizure workup (25% vs 8%, p<0.01). treatment window for thrombolysis. window (60% vs 40%, p<0.01).
Insulin resistance is a precursor condition to metabolic syndrome and type 2 diabetes, both major drivers of heart disease. Published online February 07, 2022. Poor Sleep Is A Major Risk Factor For Insulin Resistance. Insulin resistance is a significant driver of cardiovascular risk. Obesity (Silver Spring). 2023 May;31(5):1204-1215.
The outcome in real-world circumstances is known as ‘Efficacy’ Effectiveness tells us what is possible. What do you think would happen to someone's blood pressure, LDL cholesterol, or blood glucose if you were to evaluate what happens after you stop their blood pressure, cholesterol-lowering, or diabetes medication?
He had history of prior MIs and CABG, as well as diabetes, hypertension, and hyperlipidemia. Sooner identification likely leads to better outcomes, and in this case may have allowed prevention of cardiac arrest and better long-term outcome. The pain was still ongoing at arrival. He stated it was similar to prior heart attacks.
“Statins cause diabetes” This one is true. In truth, it is really those who are pre-diabetic who likely pull forward their diagnosis by about five days. But they do not magically take someone who is insulin-sensitive to full-blown type 2 diabetes overnight. But the devil is in the detail. Archives of Medical Science.
Case submitted and written by Mazen El-Baba MD, with edits from Jesse McLaren and edits/comments by Smith and Grauer A 90-year old with a past medical history of atrial fibrillation, type-2 diabetes, hypertension, dyslipidemia, presented with acute onset chest/epigastric pain, nausea, and vomiting. BP was 110 and oxygen saturation was normal.
Continuous Glucose Monitor (CGM) Management: Comparing is-CGM And rt-CGM While HbA1C and blood finger sticks have been standard tools in diabetes management, Continuous Glucose Monitor (CGM) provides a more comprehensive and accurate picture of glucose levels for better decision-making.
2 Most are balancing multiple comorbidities, such as obesity, diabetes, hypertension and chronic kidney disease (CKD). 2 Most are balancing multiple comorbidities, such as obesity, diabetes, hypertension and chronic kidney disease (CKD). 4 Approximately 6.7 million adults in the U.S. 7 Of these patients, about 55% have a LVEF 40%.
Background:Research suggests that the absolute number of strokes among people with diabetes is increasing as the population with diabetes grows. Stroke patients with poorly controlled diabetes are more likely to experience poor functional recovery, longer recovery times, recurrent stroke, and higher risk of death.
BackgroundClinical trials showed that glucagonlike peptide1 receptor agonist (GLP1RA) significantly improved the control of diabetes and reduced body weight compared with dipeptidyl peptidase 4 inhibitor (DPP4i). Primary outcome was 12month incidence of allcause death. Secondary outcome was hospitalization.
5 High intensity interval training induces beneficial effects on coronary atheromatous plaques – a randomized trial, European Journal of Preventive Cardiology , 2022;, zwac309, 6 FOURIER Steering Committee and Investigators. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease. 2006 Apr 5;295(13):1556-65.
The aim of this study was to evaluate the characteristics, comorbidities, and inpatient outcomes prevalent amongst ICH patients with hyponatremia.Methods:A retrospective study was performed for 814 adult patients admitted from January 2011-December 2022 with primary ICH at Stony Brook University Hospital.
formed a strategic collaboration for the development and commercialization of AVIM therapy for hypertensive pacemaker patients in July 2022. AVIM therapy is an investigational patented bioelectronic therapy, administered using a standard dual-chamber pacemaker, designed to immediately, substantially and persistently reduce blood pressure.
High levels of V02 Max and aerobic fitness have also been associated with lower rates of most major chronic diseases, including cancer and diabetes. Those with the very highest levels of fitness have almost nonexistent rates of type 2 diabetes 4. BMC Endocr Disord 22 , 297 (2022). The relationship is clear. J Am Coll Cardiol.
5 Over my career as a cardiovascular surgeon, as well as an immunologist, I have witnessed how current treatments for ASCVD have led to considerable improvements in outcomes, yet many patients remain vulnerable to life-threatening cardiac events.1,6 2022 Sep 6;146(10):e141]. Published 2022 Aug 6. December 22, 2022.
Those with SSI-related END have worse functional outcomes after stroke leading to increased morbidity. The primary outcome was development of END based on publishing authors’ definition. 1.39, I2=30.8%, 31 studies], diabetes mellitus (RR 1.16 Meta-regression identified that female sex [risk ratio (RR) 1.23, 95%CI 1.09-1.39,
However, it is unknown whether initiating SGLT2i during an inpatient stay for a HFrEF exacerbation results in better outcomes versus initiation post-discharge in a cohort of diabetic and non-diabetic patients.
The outcome measure was peri-procedural complications defined as a composite of perioperative death, major bleeding, contrast nephropathy, myocardial infarction, ischemic stroke, and major amputation. Notable comorbidities included diabetes mellitus at 60.6% and dialysis at 29.9%, respectively. of the participants.
They concluded that early rhythm control therapy was associated with a lower risk of adverse cardiovascular outcomes than usual care among patients with early atrial fibrillation and cardiovascular conditions. 2022 Nov 22;146(21):1561-1563. Epub 2022 Nov 21. Cleveland Clinic Journal of Medicine October 2022, 89 (10) 567-571.
Patients who received thrombolysis and subsequently underwent endovascular therapy for acute ischemic stroke between 2012 and 2022 were included. Outcomes of interest included symptomatic intracerebral hemorrhage (ICH), asymptomatic ICH, hemorrhagic transformation, mass effect and death. vs 55%, p=0.03). vs 26.6%, p=0.01).
A 65 year old with diabetes presented with a syncopal episode while sitting, associated with weakness but no chest pain or shortness of breath. Had the cardiologists followed NSTEMI or transient STEMI guidelines, which recommend non-urgent cath, the patient could have redeveloped an OMI and had a worse outcome. What do you think?
Edits by Meyers and Smith A man in his 70s with PMH of hypertension, hyperlipidemia, type 2 diabetes, CVA, dual-chamber Medtronic pacemaker, presented to the ED for evaluation of acute chest pain. This was several months after the 2022 ACC Guidelines adding modified Sgarbossa criteria as a STEMI equivalent in ventricular paced rhythm).
Adult Cardiac Surgery Database Lead Author Title Publication Date Jacob Raphael Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis The Annals of Thoracic Surgery January 2024 Joseph Sabik Multi-Arterial versus Single-Arterial Coronary Surgery: Ten Year Follow-up of One Million (..)
Program Designations Access and Publications (A&P) 1 Participant User File (PUF) 2 Task Force on Funded Research (TFR) 3 Special Projects 4 Adult Cardiac Surgery Database Lead Author Title Publication Date William Keeling 2 National Trends in Emergency Coronary Artery Bypass Grafting European Journal of Cardiothoracic Surgery October 2023 Jake (..)
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