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OAC users predominantly had cardiovascular disease and risk factors, whereas non-OAC users had higher rates of malignancy and dementia. Patients newly diagnosed with NVAF, without prior OAC use, were included.ResultsOf 23,148 adults with newly diagnosed NVAF, 11,059 (47.8%) initiated OAC within one year. Early OAC initiation (74.9%
I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.
Recent research suggested that the weight loss market was estimated to be worth $224 billion annually in 2021 and is estimated to exceed $400 billion by 2024 1. In 2021, the weight loss medication Semaglutide, which you probably know as Ozempic, was approved for the management of excess weight-causing health issues. That is until now.
Dementia Up to 40% of dementia cases could be prevented by focusing on modifiable risk factors 11. Those with high blood pressure from midlife have twice the risk of developing dementia over a 25-year follow-up 12. In most Western populations, dementia consistently ranks as a leading cause of death. 2021 Feb 16;87(1):18.
While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. Fitness & Dementia This relationship is also clearly evident when it comes to rates of dementia.
This discourse analysis study investigates the extent to which HF is discussed in general contemporary English, UK parliamentary debates and the ways in which HF is framed in discussions, when compared with two other serious health conditions, cancer and dementia. times per million words (pmw), ‘dementia’ occurs 3.68
Being a carrier of the APOE4 gene variant is associated with higher rates of the most common type of dementia, late-onset dementia. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. What to do?
We previously found that large PFO shunt is associated with increased long-term risk of vascular dementia. Our previous research revealed that PFO shunt enables the accumulation of homocysteine in circulation (Deng, Neurology 2021). However, the mechanism underlying this association remains poorly understood.
Methods and Results Patients with HF from the Swedish HF Registry between 2000-2021 were included. The highest risk was associated with dementia (hazard ratio [HR] 1.55, 95% confidence interval [CI] 1.45-1.65), In a multivariable Cox model, 12 comorbidities were independently associated with a higher risk of death from any cause.
This study aimed to evaluate the safety and feasibility of incorporating hyperacute virtual reality augmented rehabilitation (VRAR) as part of acute stroke care.MethodsA prospective, proof‐of‐concept study was conducted with 13 eligible patients who experienced hemorrhagic or ischemic stroke between July 1st, 2021, and January 1st, 2022.
Background:Cerebrovascular disease is a common cause of vascular cognitive impairment (VCI) and may progress to vascular dementia at a relatively fast rate. The participants were recruited from an outpatient Neurology clinic between May 2021 and January 2022. Stroke, Volume 55, Issue Suppl_1 , Page AWMP32-AWMP32, February 1, 2024.
The world we live in means you are massively incentivised to eat in a way that makes you gain excess weight that will likely result in metabolic dysfunction and an increased risk of not only heart disease but many cancers and also dementia. While this is unfortunate, it is the world we live in. This is a way to tackle that problem.
Background:People with stroke are at high risk of dementia. There have been reductions in stroke case fatality and disability but temporal trends in the incidence and absolute burden of post-stroke dementia have not been described.Methods:We did a population-wide analysis of over 15 million people in Ontario, Canada between 2002-2022.
Patients were randomly selected for model derivation (60%) or validation (40%). The final model predicting stroke within 1 year following cancer diagnosis was derived using multivariable Fine-Gray regression with candidate predictors selected via backward elimination. The overall rate of stroke per 1000 person-years was 6.7 (6.4 6.4 - 6.9)
Joundi’ s award-winning presentation, Abstract 67, “Risk and Time-Course of Post-Stroke Dementia: A Population-Wide Cohort Study, 2002-2022,” will be presented the morning of Feb. Target: Stroke Nationwide Quality Improvement Program 2003-2021,” will be presented during an afternoon session on Feb. Oriana Sanchez, M.D. ,
plus drug supply ASCEND PLUS (2021 – ongoing) Novo Nordisk A/S: £39.4M plus drug supply BEST-D pilot trial of vitamin D (2012-2014) Tishcon: free drug supply only Big Data Institute (2018-2021) Novartis Pharma AG Switzerland: £272K Can wearables improve the prediction of all-cause mortality, cardiovascular disease, and cancer in UK Biobank?
Cognitive Performance & Dementia. There is also mechanistic data to support its role in preventing dementia, but for now, this is more speculative 10. 2021 Jun 2;13(6):1915. Evidence suggests that supplementing with creatine leads to greater total sleep duration on training days 8. Sports Med. 8, 213–226.
A critical component of healthy ageing is the maintenance of cognitive capacity and avoidance of dementia. Muscle power may also play a role in the prevention or progression of dementia. Higher muscle power measures, such as gait (walking) speed, were associated with a 50% reduction in the risk of dementia 6. Am J Prev Med.
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