Dr. Paddy Barrett

SEPTEMBER 12, 2023

An elevated Lp(a) is the most common genetic cholesterol disorder impacting 10-20% of the population. Subscribe now The defect is not actually with the cholesterol transported in the lipoprotein particle but with alterations to a protein tail and its configuration called Kringle repeats. 2021 Aug 3;78(5):421-433.

Cholesterol 52

Cholesterol Coronary Artery Disease Heart Disease Cardiovascular Disease 52

Heart BMJ

APRIL 15, 2024

Results Forty participants were recruited between 15 March 2021 and 19 July 2022. 58% had total cholesterol >5.0 58% had total cholesterol >5.0 Participants underwent clinical cardiovascular evaluation, ECG, cardiac biomarker evaluation and CMR. Left ventricular systolic dysfunction (LVSD) was defined as LVEF <50%.

Cancer 52

Cancer Risk Factors Biomarkers Cholesterol 52

Open Heart

OCTOBER 17, 2022

Methods A multicentre cross-sectional epidemiological study to estimate the prevalence of elevated Lp(a) in patients with a history of myocardial infarction, ischaemic stroke or peripheral artery disease conducted at 949 sites in 48 countries in North America, Europe, Asia, South America, South Africa and Australia between April 2019 and July 2021.

Cardiovascular Disease 52

Cardiovascular Disease Peripheral Arterial Disease Myocardial Infarction Cholesterol 52

Dr. Paddy Barrett

DECEMBER 19, 2023

You cannot eliminate the plaque entirely, but multiple clinical trials have shown plaque regression using high-intensity cholesterol-lowering treatments, which I have discussed previously. Sci Rep 11 , 7999 (2021). 2021 Jun;14(6):1192-1202. Reversing or regressing coronary artery disease is possible. Springer, Cham. 5 Ornish, D.;

Coronary Artery Disease 105

Coronary Artery Disease Plaque Exercise Heart Attack 105

Dr. S. Venkatesan MD

JANUARY 21, 2024

(Article will be linked) We know ,HDL carries free cholesterol from peripheral cells, including macrophages and endothelial cells. This is the much famous Reverse Cholesterol Transport(RCT) and the anti-atherosclerotic effect of HDL.It 2021 Jun 25;9(7):729. This is one of the reasons we find it to understand this molecule fully.

Cholesterol 52

Cholesterol Cardiovascular Disease Article Diabetes 52

Circulation: Cardiovascular Quality & Outcomes

NOVEMBER 6, 2023

1.09]) in 2021 compared with 2019. 0.98]) and cholesterol testing (RR 0.93 [0.91-0.96]) We assessed for differential changes between low-income (&lt;138% FPL) and high-income (&gt;400% FPL) working-age adults by including an interaction term for income group and year. 1.12]), access to a provider (RR 1.12 [1.09-1.14]),

Risk Factors 40

Risk Factors Medicaid COVID-19 Outpatient 40

Stroke Journal

JANUARY 12, 2024

BACKGROUND:Small dense low-density lipoprotein cholesterol (sdLDL-C) particles are more atherogenic than large and intermediate low-density lipoprotein cholesterol (LDL-C) subfractions. Incident carotid plaques and their vulnerability were detected by carotid ultrasound at follow-up (2021). Stroke, Ahead of Print.

Plaque 40

Plaque Cholesterol Ultrasound Stenosis 40

Journal of the American Heart Association

FEBRUARY 7, 2024

We searched MEDLINE, Embase, and Cochrane Library up to July 2, 2021 and updated a meta‐analysis of cardiovascular statin trials published in 2012. Among our several subgroup analyses, we looked at difference depending on stroke status and also depending on age.

Hemorrhage 40

Hemorrhage Strokes Stroke Cholesterol 40

Dr. Paddy Barrett

FEBRUARY 13, 2024

Be satiating Low in sugar In a Carbohydrate/Fat Balance that suits your preference and doesn’t drive your LDL cholesterol through the roof. You get to choose how you are going to spend these 1,462 calories. My advice is: It should come from real foods. Subscribe now Now, you get to choose your restriction.

Diet 105

Diet Diabetes Exercise Kidney Disease 105

Cardiometabolic Health Congress

JANUARY 3, 2024

Food and Drug Administration (FDA) in 2021 as a once-weekly injection for chronic weight management in adults with obesity and at least one weight-related condition such as type 2 diabetes or hypertension. Among these options is semaglutide (Wegovy), a medication that has gained attention for its effectiveness in aiding weight loss efforts.

Obesity 97

Obesity Diabetes Blood Pressure BMI 97

SoftCath

OCTOBER 31, 2021

Using digital cardiac care tools resulted in an increase considering their positive role in monitoring health through: Smoking cessation Weight loss programs Optimised blood pressure control Glycemic control in diabetes Lipid and cholesterol levels Recommended Read: Medical Imaging Emerging Trends in 2021 2.

COVID-19 52

COVID-19 Innovation Cardiac Rehabilitation Cardiovascular Disease 52

Dr. Paddy Barrett

AUGUST 16, 2024

What do you think would happen to someone's blood pressure, LDL cholesterol, or blood glucose if you were to evaluate what happens after you stop their blood pressure, cholesterol-lowering, or diabetes medication? 2021 Mar 18;384(11):989-1002. I told you they didn’t work. ” But let me ask you this. Med Clin North Am.

Obesity 52

Obesity Blood Pressure Diet Exercise 52

Dr. Paddy Barrett

DECEMBER 27, 2024

Non-HDL Cholesterol There is no ‘Good’ cholesterol on a standard cholesterol blood test. There really is only bad cholesterol. The relationship is simple—higher cholesterol for longer increases your risk of coronary artery disease 4. A 40-year-old male with a Non-HDL cholesterol of 5.0

Coronary Artery Disease 103

Coronary Artery Disease Blood Pressure Cholesterol Heart Disease 103

Frontiers in Cardiovascular Medicine

FEBRUARY 25, 2025

This study aimed to comprehensively analyze the burden of IHD, its risk factors, and future trends from 1990 to 2021 using the Global Burden of Disease database.MethodsWe assessed IHD trends in incidence, prevalence, mortality, and disability-adjusted life years (DALYs) stratified by age (greater than 15 years) and gender.

Risk Factors 52

Risk Factors Heart Disease Blood Pressure Public Health 52

Dr. Paddy Barrett

SEPTEMBER 20, 2024

The fundamental cause of atherosclerosis is when a cholesterol particle crosses into the artery wall from the bloodstream, gets stuck, and sets off an inflammatory process 1. Every cholesterol particle has a protein marker called ApoB on its outside. Every cholesterol particle has a protein marker called ApoB on its outside.

Heart Disease 111

Heart Disease Cholesterol Atherosclerosis Heart Attack 111

DAIC

JUNE 14, 2024

Getty Images milla1cf Fri, 06/14/2024 - 19:30 June 14, 2024 — Until now, known risk factors for cardiac arrest have been limited to cardiovascular conditions such as hypertension and high cholesterol. million patients who sought care between 2010 and 2021 at UW Medicine, a large academic healthcare system in Seattle.

Cardiac Arrest 116

Cardiac Arrest Public Health Risk Factors Research 116

CardiacWire

JANUARY 31, 2025

is at an all time high, with 942k cardiovascular disease-related deaths in 2022, up by 10k from 2021. However, theres light at the end of the cardiovascular tunnel thanks to advancements in drugs like GLP-1s and new cholesterol controls, which mean heart disease isnt a death sentence like it used to be. adults have CVD.

Cardiovascular Disease 59

Cardiovascular Disease Obesity Heart Disease Public Health 59

Dr. Paddy Barrett

JUNE 21, 2024

He had high blood pressure and high cholesterol most of his life, and he wasn’t great at taking his tablets.” Lipoprotein (a) Lipoprotein (a) or Lp(a), pronounced “L P Little A”, is the most common genetic cholesterol particle disorder in the population. “Dad had a heart attack at 78.

Heart Disease 88

Heart Disease Heart Attack Heart attacks Coronary Artery Disease 88

Dr. Paddy Barrett

JANUARY 23, 2024

The average Non-HDL cholesterol for western populations is 3.6 The average Non-HDL cholesterol is 2.9 2021 Dec 1;53(12):2512-2519. 2021 Feb 16;87(1):18. Share Lipids Hyperlipidemia is a primary risk factor for the development of atherosclerosis. mmol/l (112 mg/dl), which equates to the 20th percentile. Circulation.

Heart Disease 105

Heart Disease Blood Pressure Dementia Atherosclerosis 105

Stroke Journal

JANUARY 30, 2025

Incident stroke (ischemic and hemorrhagic) was ascertained until the end of 2021 with adjudication by an expert panel. Cox regression was used to estimate the hazard ratio (HR) for incident stroke per doubling of EIC levels, and p-values were FDR corrected. Results:Among the 9,444 participants included, the mean age was 57 (5.7 SD), and 43.2%

Atherosclerosis 40

Atherosclerosis Strokes Stroke Atrial Fibrillation 40

Physiologically Speaking

MARCH 6, 2024

Statins lower cholesterol. Hawley - 2021 - The Journal of Physiology - Wiley Online Library While an exercise pill could certainly activate one or a few of the pathways in the body that exercise does, the scope would be extremely narrow. For one, drugs target single pathways or risk factors. Unfortunately, this isn’t possible.

Exercise 92

Exercise Blood Pressure Risk Factors Physiology 92

Dr. Smith's ECG Blog

JANUARY 23, 2024

Other than being overweight and having an elevated cholesterol she was healthy. For those interested in additional examples of AV block ( including laddergram illustration ) — Please check out My Comment at the bottom of the page in the May 16, 2020 post — the October 25, 2021 post and — the July 30, 2023 post — and, the April 6, 2023 post ).

Tachycardia 106

Tachycardia Arrhythmia Heart Disease Sudden Cardiac Death 106

DAIC

JANUARY 23, 2024

Inflammation driven by signaling cytokines, circulating immune cells, adhesion molecules, and oxidized low-density lipoprotein cholesterol (LDL-C) leads to atherosclerotic plaque development, plaque progression, and eventual rupture.14,15 2021 Apr 20;77(15):1958-1959]. Roth GA, Mensah GA, Johnson CO, et al. J Am Coll Cardiol.

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

DAIC

MAY 16, 2024

Risk factors for PAD include smoking; having Type 1 or Type 2 diabetes, high blood pressure, high cholesterol, chronic kidney disease, atherosclerosis in other parts of the body (such as coronary artery disease); and being age 75 years or older. and Global Data From the American Heart Association.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Dr. Paddy Barrett

AUGUST 29, 2023

Share JUPITER In 2008 a landmark paper was published showing that in people without cardiovascular disease and relatively normal LDL-cholesterol (<3.4 Because of the increased risk, I am also quicker to introduce non-statin-based cholesterol-lowering agents such as ezetimibe, bempedoic acid, PCSK9 inhibitors or inclisiran when available.

Diabetes 52

Diabetes Risk Factors Heart Attack Heart attacks 52

Dr. Malcolm Kendrick

DECEMBER 5, 2024

In my opinion, or should I say ‘allegedly’ what actually happened here was that Barney Calman had heard from various cardiology experts that cholesterol and statin ‘deniers’ were causing people to stop taking their drugs. Sorry, I know the answer to that. What actually happened? Had Barney ever read any of it?

Article 104

Article Cholesterol Public Health Research 104

DAIC

APRIL 29, 2024

Getty Images milla1cf Mon, 04/29/2024 - 13:06 April 29, 2024 — Women with heart disease are less often treated with cholesterol-lowering drugs than men, according to research presented today at ESC Preventive Cardiology 2024 , a scientific congress of the European Society of Cardiology ( ESC ).1 80 years or older).

Heart Disease 104

Heart Disease Cholesterol Heart Attack Heart attacks 104

DAIC

MARCH 8, 2024

13 Obesity increases the risk of developing high blood pressure or high blood cholesterol, both contributing factors to CVD. 21, 25 May 2021. 6,8 Obesity is influenced by a variety of factors, including genetics, social determinants of health, and the environment. 10,11 In the U.S., about 42% of adults live with obesity.

Obesity 111

Obesity Heart Disease Heart Attack Heart attacks 111

Dr. Malcolm Kendrick

OCTOBER 30, 2024

I, Dr Malcolm Kendrick, with or without other co-conspirators, would be accused of spreading misinformation about cholesterol and statins. The hypothesis that a raised cholesterol level causes heart disease [atherosclerotic cardiovascular disease (ASCVD)] is possibly the single most powerful idea in medicine. With thousands dying.

Cholesterol 145

Cholesterol Article Research Diet 145