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As the line goes: “You can’t outrun a bad diet, and you can’t out diet not exercising.” The DiRECT Trial used a calorie-restricted diet over 3-5 months and also withdrew diabetic and blood pressure control medications. All of these patients had a BMI >27. ” Diabetes. Answer: Low Calorie.
Even in diabetics of normal weight (BMI<27), weight loss can reverse diabetes 2. Please go and read every single GLP-1 trial on weight loss (Average 15 kg) and show me where they got everyone to go on an extremely low-carb diet to avoid insulin spikes. That’s not to say that using a low-carb diet is not effective.
Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. The distinction here is the metabolic consequences of excess fat causing a health risk rather than focusing on the BMI cutoff.
Food and Drug Administration ( FDA ) has approved an additional indication for Wegovy ( semaglutide ) to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight along with a reduced calorie diet and increased physical activity.
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