Journal of the American Heart Association

DECEMBER 24, 2024

BackgroundIn obstructive hypertrophic cardiomyopathy, myectomy improves symptoms, quality of life, and left ventricular (LV) outflow tract gradients. P=0.24) or Kansas City Cardiomyopathy Questionnaire summary score change (r=0.02,P=0.85), P=0.85), whereas it was significantly associated with change inE/e (r=0.29,P=0.003).ConclusionsIn

Cardiomyopathy 40

Cardiomyopathy Quality of Life 40

Open Heart

APRIL 6, 2022

Objective This study summarises the diagnostic validity and clinical utility of genetic testing for patients with hypertrophic cardiomyopathy (HCM) and their at-risk relatives. Methods A systematic search was performed in PubMed (MEDLINE), Embase, CINAHL and Cochrane Central Library databases from inception through 2 March 2020.

Cardiomyopathy 52

Cardiomyopathy Article 52

Circulation

NOVEMBER 6, 2023

While there are several potential reasons for the lack of benefit, an underexplored possible reason is the presence of coincidental non-ischemic cardiomyopathy (NICM). We identified the presence and cause of cardiomyopathy using CMR and coronary angiography data, blinded to clinical outcomes. had no cardiomyopathy (CAD+noCM), 64.8%

Coronary Artery Disease 40

Coronary Artery Disease Cardiomyopathy Hospital Outcomes 40

Circulation: Arrhythmia and Electrophysiology

FEBRUARY 3, 2025

BACKGROUND:Over the past decades, hypertrophic cardiomyopathy has become a contemporary treatable disease. There was a significant decline in the rates of sudden cardiac death from 1990 (0.84%/y) to 2020 (0.31%/y).CONCLUSIONS:Dramatic Circulation: Arrhythmia and Electrophysiology, Ahead of Print.

Sudden Cardiac Death 40

Sudden Cardiac Death Defibrillator Cardiomyopathy Outcomes 40

Circulation

NOVEMBER 14, 2024

BACKGROUND:The ability to predict recovery of left ventricular ejection fraction (LVEF) in response to guideline-directed therapy among patients with nonischemic cardiomyopathy is desired. Patients had recent-onset nonischemic cardiomyopathy defined by LVEF 45% and development of symptoms or signs of heart failure within the past 6 months.

Cardiomyopathy 40

Cardiomyopathy Heart Failure Circulation 40

Journal of the American Heart Association

MARCH 25, 2025

BackgroundDedicated hypertrophic cardiomyopathy (HCM) center cohorts have reported reductions in HCMrelated deaths, likely due to the introduction of contemporary treatments. Excess HCMrelated deaths were estimated during the 2020 to 2022 COVID19 pandemic. Journal of the American Heart Association, Ahead of Print.

COVID-19 40

COVID-19 Cardiomyopathy Certification Cardiovascular Disease 40

Circulation

NOVEMBER 11, 2024

Finally, LV-GLS provided incremental prognostic value over 2020 American College of Cardiology (ACC)/American Heart Association (AHA) risk model (log-likelihood ratios, -262.2 004 for 2020 AHA guideline and 2022 ESC guideline, respectively).Conclusion:Feature to 3.36]) after adjustment for known risk factors. vs -266.2; vs -264.9;

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Defibrillator Risk Factors 40

Journal of Cardiovascular Electrophysiology

MARCH 3, 2024

Complete left bundle branch block (CLBBB)-like QRS morphology of right ventricular pacing at pacemaker implantation satisfying the American Heart Association/American College of Cardiology Foundation/Heart Rhythm Society criteria of CLBBB was associated with development of pacing induced cardiomyopathy.

Cardiomyopathy 40

Cardiomyopathy Pacemaker Heart Rhythm Atrial Fibrillation 40

DAIC

DECEMBER 19, 2023

Prior to 2020, studies mapping the electrical activity of the heart had 20 or 30 patients at most. The vest is currently being used to map the hearts of people with diseases such as hypertrophic cardiomyopathy and dilated cardiomyopathy. The vest has since been used successfully in 800 patients.

Sudden Cardiac Death 105

Sudden Cardiac Death Heart Rhythm Biomarkers Cardiomyopathy 105

Dr. Smith's ECG Blog

JUNE 23, 2023

A 50-something male with unspecified history of cardiomyopathy presented in diabetic ketoacidosis (without significant hyperkalemia) with a wide complex tachycardia and hypotension. The fact that he has a cardiomyopathy argues for a more typical ventricular tachycardia, as does the absence of rSR' in lead V1. It is regular.

Tachycardia 52

Tachycardia Cardiomyopathy Arrhythmia Diabetes 52

Dr. Smith's ECG Blog

DECEMBER 26, 2023

This is a very typical ECG for Hypertrophic Cardiomyopathy. The most recent previous was 4 years prior, and was in the normal range) Elderly patients, and patients with cardiomyopathy (including HOCM), may have troponin values in this range chronically ("chronic myocardial injury").

Chest Pain 93

Chest Pain Cardiomyopathy Blog AFIB 93

Dr. Smith's ECG Blog

DECEMBER 13, 2023

For technical reasons — P waves are not well visible in this tracing — BUT — the P wave in lead I appears to be larger than the P wave in lead II , which is often a tip-off to LA-LL Reversal ( See My Comment in the November 19, 2020 and the May 24, 2022 posts in Dr. Smith's ECG Blog ).

Blog 123

Blog Chest Pain Cardiac Arrest Cardiomyopathy 123

Dr. Smith's ECG Blog

OCTOBER 15, 2023

Taking a Closer LOOK: We have periodically reviewed cases with low voltage in Dr. Smith’s ECG Blog ( Please see My Comment at the bottom of the page in the November 12, 2020 post, among others ). 12, 2020 post — are 2 causes potentially relevant to my initial considerations in today’s patient, who was found to have acute LAD OMI.

Chest Pain 116

Chest Pain Cardiomyopathy STEMI Blog 116

Circulation: Heart Failure

FEBRUARY 1, 2024

Candidates listed for rare causes of HF significantly differed in baseline characteristics and had more frequent score exceptions compared with other cardiomyopathies (31.3%, 32.0%, 36.4%, and 16.7% for patients with hypertrophic cardiomyopathy, RCM, congenital heart disease, and other cardiomyopathies). and 0.40, respectively).

Heart Failure 40

Heart Failure Congenital Heart Disease Congenital Cardiomyopathy 40

Dr. S. Venkatesan MD

JULY 1, 2024

In simple terms it mimics a heart of Hypertrophic cardiomyopathy, which we know has brisk ejection. We can also understand the principles of the management of cardiomyopathy from a Giraffe’s heart. This forms the basis behind the ventricular reduction and reconstruction surgery for Ischemic dilated cardiomyopathy.(Batisda

Cardiomyopathy 52

Cardiomyopathy Aortic valve Aortic Blood Pressure 52

Dr. Smith's ECG Blog

APRIL 12, 2023

Example here: DIffuse ST Elevation with Apical Ballooning: is it Takotsubo Stress Cardiomyopathy? In comparison to the previous study, 11/11/2020, there has been a significant interval deterioration of left ventricular systolic function (previous EF 80%), and there is a new large apical wall motion abnormality.

Echocardiogram 52

Echocardiogram Pulmonary Cardiomyopathy Coronary Artery Disease 52

Ken Grauer, MD

AUGUST 22, 2024

PEARL # 4: As alluded to above — the finding of a Tall R Wave in Lead V1 should prompt consideration of the following LIST of the 6 most common Causes: i ) WPW; ii ) RBBB; iii ) RVH; iv ) Posterior MI; v ) HCM ( Hypertrophic CardioMyopathy ); and , vi ) Normal variant — as a diagnosis of exclusion ( See ECG Blog #81 for more on this issue ).

Blog 101

Blog STEMI Tachycardia Cardiomyopathy 101

Dr. Smith's ECG Blog

SEPTEMBER 2, 2024

Arrhythmogenic cardiomyopathy Long QT syndrome Hypertrophic cardiomyopathy. That said — in a patient who develops TdP — the overall ECG appearance of this initial ECG is consistent with low K+ and/or low Mg++ ( See My Comment in the May 9, 2020 post — for more on the ECG diagnosis of hypokalemia and hypomagnesemia ).

Tachycardia 113

Tachycardia Blog Sudden Cardiac Death Arrhythmia 113

Heart BMJ

NOVEMBER 27, 2023

Methods The Outcomes Registry for Cardiac Conditions in Athletes was a nationwide prospective multicentre observational cohort study that captured testing and outcomes data from 45 institutions (September 2020–June 2021). Athletes with an ECG and transthoracic echocardiogram (TTE) and no pre-existing conditions were included.

COVID-19 52

COVID-19 Sudden Cardiac Death Aortic Atrial Fibrillation 52

Dr. Smith's ECG Blog

SEPTEMBER 16, 2024

The patient was diagnosed with stress cardiomyopathy. Widespread T wave inversions and prolongation of the QT interval is not uncommon in Takotsubo cardiomyopathy. The QTc then gradually shortened over the course of several days as is usual for stress cardiomyopathy. Potassium was 4,8 mmol/l. ( ref 3,5-4,6 mmol/l ).

Cardiac Arrest 67

Cardiac Arrest Cardiomyopathy Arrhythmia Atrial Fibrillation 67

DAIC

OCTOBER 2, 2024

Director of the Hypertrophic Cardiomyopathy Center at the Lahey Hospital and Medical Center. Impact of Aficamten on Disease and Symptom Burden in Obstructive Hypertrophic Cardiomyopathy: Results from SEQUOIA-HCM. CVrg: Heart Failure 2020-2029, p 44; Maron et al. CVrg: Heart Failure 2020-2029, p 44; Maron et al.

Cardiomyopathy 40

Cardiomyopathy Sudden Cardiac Death Biomarkers Heart Failure 40

Open Heart

AUGUST 25, 2023

Background Consensus guidelines support the use of implanted cardioverter-defibrillators (ICD) for primary prevention of sudden cardiac death in patients with either non-ischaemic or ischaemic cardiomyopathy with left ventricular ejection fraction (LVEF) ≤35%.

Defibrillator 52

Defibrillator Sudden Cardiac Death Myocardial Infarction Echocardiogram 52

Dr. S. Venkatesan MD

SEPTEMBER 3, 2024

Recognizing non-sarcomeric Hypertrophic Cardiomyopathy (HCM) by echocardiography is one such task.It With all all these advancements ,how good is echocardiography in ruling out (or in) reversible /treatable HCM mimickers or their molecular subsets. Amyloid -HCM coexistence Medical pathology is never a pure science.It

Bicuspid/Mitral 52

Bicuspid/Mitral Cardiomyopathy Tricuspid Academic 52

Dr. Smith's ECG Blog

OCTOBER 23, 2023

The most important clinical entity associated with motion alternans is large pericardial effusion — though motion alternans has also been observed in some cases of hypertrophic cardiomyopathy. It is important to appreciate that not all pericardial effusions produce electrical alternans.

Tachycardia 130

Tachycardia Cardiac Arrest ICU Blog 130

Dr. Smith's ECG Blog

FEBRUARY 16, 2020

In other words, the severely increased end diastolic pressure from the extremely poor LV function caused by the myocarditis results in extremely poor coronary perfusion pressure. == MY Comment by K EN G RAUER, MD ( 2/16/2020 ): == As per the title by Dr. Smith — this case was not what I thought. 109 (20):361-368, 2012 — CLICK HERE ).

Cardiogenic Shock 52

Cardiogenic Shock STEMI Pericarditis Blog 52

Ken Grauer, MD

DECEMBER 12, 2024

Working through a case of a regular WCT Rhythm in this 80-something woman See My Comment in the May 5, 2020 post on Dr. Smiths ECG Blog. Another case of a regular WCT Rhythm in a 60-something woman See My Comment at the bottom of the page in the April 15, 2020 post on Dr. Smiths ECG Blog. Smiths ECG Blog.

Blog 82

Blog Tachycardia Heart Disease Congenital Heart Disease 82

DAIC

FEBRUARY 29, 2024

24: Joint American College of Cardiology/Journal of the American College of Cardiology Late-Breaking Clinical Trials (Session 402) Saturday, April 6 9:30 – 10:30 a.m. 12:15 p.m.

Aortic valve 103

Aortic valve Myocardial Infarction Aortic Blood Pressure 103

Circulation

NOVEMBER 11, 2024

Data was obtained from the Hospital Corporation of America (HCA) enterprise-wide database from January 2020 to September 2023 using the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM).

Heart Failure 40

Heart Failure Cardiac Arrest Kidney Disease Atrial Fibrillation 40

Dr. Smith's ECG Blog

JANUARY 23, 2024

The granulomatous inflammation affects the heart, causing an infiltrative cardiomyopathy The most common manifestations of cardiac sarcoidosis are atrioventricular (AV) block and ventricular tachyarrhythmias (VT). Lung involvement is the typical presentation. Cardiac sarcoidosis (CS) is seen in ~10% of patients with sarcoidosis.

Tachycardia 107

Tachycardia Arrhythmia Heart Disease Sudden Cardiac Death 107

Dr. Smith's ECG Blog

OCTOBER 28, 2023

See this even more interesting and more dramatic and fascinating case: History of Hypertrophic Cardiomyopathy (HOCM), with Tachycardia and High Lactate = My Comment by K EN G RAUER, MD ( 10/28 /2023 ): = QUESTION: For clarity in Figure-1 — I've reproduced today's ECG without the long lead rhythm strip. 23/WCC — 2/21/2020 ).

Preserved Ejection Fraction 57

Preserved Ejection Fraction Sudden Cardiac Death Chest Pain Heart Failure 57

Ken Grauer, MD

JANUARY 13, 2024

HCM is an "umbrella term" applied to the presence of LVH in the absence of "abnormal cardiac loading conditions" ( Hughes et al — JAHA 9:e015294, 2020 ). . = A bout H CM ( Different Forms of this Entity ): I've excerpted what appears below from My Comment in the December 26, 2023 post in Dr. Smith's ECG Blog.

Blog 159

Blog Ischemia AFIB Hypertension 159

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

Angiogram No obstructive epicardial coronary artery disease Cannot exclude non-ACS causes of troponin elevation including coronary vasospasm, stress cardiomyopathy, microvascular disease, etc. hours T-wave are getting larger again The patient went for an angiogram at about 7 hours after arrival. This is not the case.

Coronary Angiogram 109

Coronary Angiogram Plaque Thrombosis STEMI 109

Wellnest

JUNE 1, 2023

The World Health Organisation (WHO) formally proclaimed COVID-19, the illness spread by a zoonotic SARS-CoV-2, as a pandemic in March 2020, after it had started to spread in late 2019. Even though the pandemic is on the wane, new studies and evidence about it continue to emerge.

COVID-19 52

COVID-19 Myocardial Infarction Thrombosis Electrocardiogram 52

Dr. S. Venkatesan MD

FEBRUARY 20, 2024

2020) The un-disputable fact is ischemic DCM has a target to treat, though it is termed as cardiomyopathy. Please remember we don’t deny an ICD for a sarcoid cardiomyopathy or end-stage HCM just because they are non-ischemic. Circulation. 2022 Feb 8;145(6):427-436. CRT -P vs CRT-D Samy M, Hamdy RM.

Defibrillator 52

Defibrillator Heart Failure Sudden Cardiac Death Cardiomyopathy 52

Ken Grauer, MD

JULY 15, 2023

Subsequent testing supported the presumption of apical cardiomyopathy as the cause of this patient's sustained VT. ie, Severe subendocardial ischemia from sustained VT in a patient severe apical cardiomyopathy resulted in a peak troponin >31,000 ng/L in today's case ). CT coronary angiogram showed no obstructive coronary disease.

Blog 78

Blog Coronary Angiogram Cardiomyopathy Ischemia 78

Dr. S. Venkatesan MD

MARCH 19, 2024

Brandão M, Desmoplakin Cardiomyopathy: Comprehensive Review of an Increasingly Recognized Entity. The 2020 “Padua Criteria” for Diagnosis and Phenotype Characterization of Arrhythmogenic Cardiomyopathy in Clinical Practice. J Clin Med. J Clin Med. 2022 Jan 5;11(1):279. doi: 10.3390/jcm11010279.

Arrhythmia 52

Arrhythmia Sudden Cardiac Death Electrophysiology Cardiomyopathy 52

Dr. Smith's ECG Blog

JUNE 21, 2024

A patient in the ICU with significant underlying cardiac disease [HFrEF 30%, non-ischemic cardiomyopathy, LBBB s/p CRT-D (biventricular pacer), AVNRT s/p ablation a few yrs ago, hx sinus tachycardia while on max tolerated BB therapy] went into a regular wide-complex tachycardia after intubation for severe COPD exacerbation.

Tachycardia 71

Tachycardia Atrial Fibrillation Pacemaker Blog 71