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Novartis Reclaims Anthos, Reenters Factor XI Race

CardiacWire

Novartis spun out the testing and development of abelacimab and formed Anthos Therapeutics back in 2019. Bayer terminated its OCEANIC-AF trial for its Factor XI inhibitor, asundexian, due to 3x greater stroke (1.3% vs. 0.4%) and 4x higher ischemic stroke rates (csHR = 4.06).

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Cardiovascular outcomes in long COVID-19: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

Systematic search conducted without language restrictions from December 1, 2019 to June 31, 2022 on PubMed, EMBASE, Web of Science, Cochrane library, ProQuest Coronavirus Research Database, COVID-19 Living Overview of the Evidence (L-OVE) subset of Episteminokos and the World Health Organization (WHO) Covid-19 databases.

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Adherence to Physical Activity Recommendations Among Stroke Survivors in the United States

Stroke Journal

Stroke, Volume 56, Issue 1 , Page 113-121, January 1, 2025. BACKGROUND:Physical activity is an effective modifiable behavior for preventing recurrent strokes. This study aims to determine the adherence to physical activity recommendations among stroke survivors in the United States. versus 62.3%;P<0.0001). versus 67.9%;P<0.0001];

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Abstract WP235: Cannabis Use Disorder in Elderly Stroke Survivors (?65 Years) Elevates the Risk of Stroke Recurrence: An Analysis From the National Inpatient Sample (2016-2019)

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWP235-AWP235, February 1, 2024. Introduction:Amid the rising prevalence of cannabis use disorder (CUD) in older adults and with surveys reporting ~85% of overlapping use for medicinal and recreational purposes in American cannabis users, the link between CUD and stroke is paramount. vs. 28.4%).

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Predicting cardiac arrhythmia 30 minutes before it happens

Science Daily - Heart Disease

Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal.

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Findings from MOST Trial Presented at ISC24: Blood thinners added to clot-busting medication did not improve stroke outcomes

DAIC

Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. A lot of our approaches in stroke treatment were learned from how we treat heart attacks.

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Abstract TMP98: Pre-Stroke Use of Blood-Brain Barrier Crossing Angiotensin Receptor Blockers in Elderly Patients Mitigates Neurological Severity at the Onset of Acute Stroke

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page ATMP98-ATMP98, February 1, 2024. Introduction:Functional outcomes after acute stroke (AS) are related to the initial neurological severity. We defined MNS as a score of ≤5 points on the National Institutes of Health Stroke Scale.

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