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Novartis spun out the testing and development of abelacimab and formed Anthos Therapeutics back in 2019. Bayer terminated its OCEANIC-AF trial for its Factor XI inhibitor, asundexian, due to 3x greater stroke (1.3% vs. 0.4%) and 4x higher ischemic stroke rates (csHR = 4.06).
Systematic search conducted without language restrictions from December 1, 2019 to June 31, 2022 on PubMed, EMBASE, Web of Science, Cochrane library, ProQuest Coronavirus Research Database, COVID-19 Living Overview of the Evidence (L-OVE) subset of Episteminokos and the World Health Organization (WHO) Covid-19 databases.
Stroke, Volume 56, Issue 1 , Page 113-121, January 1, 2025. BACKGROUND:Physical activity is an effective modifiable behavior for preventing recurrent strokes. This study aims to determine the adherence to physical activity recommendations among stroke survivors in the United States. versus 62.3%;P<0.0001). versus 67.9%;P<0.0001];
Stroke, Volume 55, Issue Suppl_1 , Page AWP235-AWP235, February 1, 2024. Introduction:Amid the rising prevalence of cannabis use disorder (CUD) in older adults and with surveys reporting ~85% of overlapping use for medicinal and recreational purposes in American cannabis users, the link between CUD and stroke is paramount. vs. 28.4%).
Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal.
Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. A lot of our approaches in stroke treatment were learned from how we treat heart attacks.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP98-ATMP98, February 1, 2024. Introduction:Functional outcomes after acute stroke (AS) are related to the initial neurological severity. We defined MNS as a score of ≤5 points on the National Institutes of Health Stroke Scale.
7-9, and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health. 7-9, and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health. The meeting will be held in Phoenix, Feb. The meeting will be held in Phoenix, Feb.
Stroke, Volume 55, Issue Suppl_1 , Page A13-A13, February 1, 2024. Elderly obese stroke survivors (> 65 years) having a recurrent acute ischemic stroke (AIS), with or without prior bariatric surgery (PBS), were identified using ICD-10 codes. Both groups (PBS vs. no PBS) were predominantly female (59.7% vs. 90.7%).
Stroke, Ahead of Print. BACKGROUND:Stroke triggers are factors that may precipitate a stroke within a given time interval and can predict the timing of a stroke. More research is needed to assess the link between the severity of hypoglycemia and stroke occurrence, as well as the severity of the stroke.
BACKGROUND:Cardiovascular disease and stroke are common and costly, and their prevalence is rising. to 3.8%), stroke (3.9% Circulation, Ahead of Print. in 2020 to 61.0% The prevalences of poor diet, inadequate physical activity, and smoking are estimated to improve over time, whereas inadequate sleep will worsen. to 15.0%) will rise.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP100-ATMP100, February 1, 2024. Introduction:Rising obesity rates and the increasing prevalence of stroke in the metabolically healthy obese (MHO) necessitate examining its association in younger (18-44 year) populations.
MethodsSix centers in China participated in this prospective, multicenter study of PFO closure from June 2019 to September 2020. Except for 2 cases (1.4%) of micropericardial effusion, there were no other complications such as cardiac tamponade, major bleeding, stroke oroccluder embolization. The procedural success rate was 99.3%.
Stroke, Volume 55, Issue Suppl_1 , Page ATP120-ATP120, February 1, 2024. Background:Racial disparities in stroke prevalence and outcomes have been well documented in previous studies, but there is not sufficient data based on post-menopausal women. Demographics were analyzed after stratifying the population by race. were white, 16.5%
This underuse of anticoagulants for stroke prevention has been cited as one of the greatest public health issues facing cardiovascular patients 6. Many doctors are put in the unfortunate position of having to weigh the risk of stroke against the risk of bleeding for their patients with AFib, said Christian T. Nat Rev Cardiol.
Stroke, Ahead of Print. BACKGROUND:Obtaining timely informed consent is a key barrier in acute ischemic stroke clinical trial recruitment. eConsent in acute ischemic stroke clinical trials, however, is limited and understudied. eConsent in acute ischemic stroke clinical trials, however, is limited and understudied.
Stroke, Volume 56, Issue Suppl_1 , Page ATP62-ATP62, February 1, 2025. Introduction:Education for post-acute stroke patients is crucial for several reasons: recovery and rehabilitation, prevention of recurrence, empowerment, caregiver support, and health literacy. The data for 2023 reflects a continuation of this positive trend.
Stroke, Volume 55, Issue Suppl_1 , Page A35-A35, February 1, 2024. The University of Minnesota partnered with the M Health Fairview (MHFV) System to incorporate stroke clinical trials into the annual comprehensive stroke education courses.
Stroke, Volume 56, Issue Suppl_1 , Page ATP136-ATP136, February 1, 2025. Once these post-stroke patients have been identified, they are given a personalized monitoring plan depending on the individuals risk factors, the personalized care and rehabilitation plans are tracked and followed.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. A prior published analysis of national trends after one year in mechanical thrombectomy use and outcomes for stroke before and after publication of the 2015 US guideline update showed improved functional outcomes and lower peri‐procedural mortality.
about 12 infants in 1,000 births have a congenital heart defect, according to the Associations 2025 Heart Disease and Stroke Statistics. million live births from the Korean National Health Insurance Service database from 2005 to 2019. In the U.S., Researchers analyzed health information about more than 3.5
Stroke, Volume 56, Issue Suppl_1 , Page A122-A122, February 1, 2025. Introduction:Standardized stroke response protocols have been shown to reduce Door to Puncture (DTP) times for Acute Ischemic Strokes (AIS), potentially improving functional outcomes and reducing mortality. This reduction time is equivalent to 22.8
Stroke, Volume 56, Issue Suppl_1 , Page AWP268-AWP268, February 1, 2025. Introduction:The overall composition of stroke subtype is typically stable within biogeographical groups. Whether the COVID-19 pandemic impacted stroke etiology is still being investigated, but most studies have been performed outside the United States.
Stroke, Volume 56, Issue Suppl_1 , Page ATP270-ATP270, February 1, 2025. Introduction:Syphilis is associated with increased risk of cerebrovascular disease and acute stroke; stroke may even be the initial clinical manifestation of syphilis (Images 1 and 2). between 2016-2019, but then dropped to 1.02% in 2020.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP73-ATMP73, February 1, 2024. We aim to better understand this risk and its impact on in-hospital outcomes over a longitudinal time period in a large population based sample.Methods:We analyzed the 2000-2019 National Inpatient Sample, selecting for aneurysmal SAH (aSAH).
The primary outcome was atherothrombotic major adverse cardiovascular events as a composite outcome of cardiovascular mortality, nonfatal stroke, and nonfatal myocardial infarction. Patients were propensity matched in a 1:1 ratio using a caliper distance of 0.2 without replacement.
Stroke, Volume 55, Issue Suppl_1 , Page AHUP16-AHUP16, February 1, 2024. Introduction:Recent reports demonstrate that stroke prevalence is expanding in young women, especially in diverse populations. In the total population, 25% had an intracerebral hemorrhage, 56% had an ischemic stroke, and 19% had a subarachnoid hemorrhage.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP21-ATMP21, February 1, 2024. Background:Medical comorbidities and stroke risk factors explain only a proportion of stroke incidence and outcomes in different populations. The primary outcome measure was discharge to home.
Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. Of the ischemic strokes, 22% were small-vessel occlusion, 8% large artery atherosclerosis, 21% cardioembolic, and 49% cryptogenic/other determined etiology.
Stroke, Volume 55, Issue Suppl_1 , Page AWP17-AWP17, February 1, 2024. Introduction:The launch of AHA’s Target: Stroke Phase III in 2019 challenged stroke centers to achieve DTN times ≤ 30 min of arrival to ≥ 50% of AIS patients treated with IV thrombolytics.
Stroke, Volume 54, Issue 12 , Page 3128-3137, December 1, 2023. BACKGROUND:Both social service resources and stroke prevalence vary by geography, and health care resources are scarcer in rural areas. Models were sequentially adjusted for total population and CT demographics.RESULTS:In Ohio, stroke prevalence was 3.9% (0.4%–14.2%).
Stroke, Volume 55, Issue Suppl_1 , Page AWP263-AWP263, February 1, 2024. The concentration of equol was measured using liquid chromatography-mass spectrometry.Results:Eighty-five patients with stroke (43.5%) and 50 healthy subjects (48.5%) were equol producers (p=0.32). p=0.04) among patients with ischemic stroke.
Data on major cardiovascular events (MACE; mortality, myocardial infarction, stroke, heart failure) through December 2021 were obtained from national registries. Trend analyses for the years 2010–2019 revealed improved one-year MACE in patients with diabetes and CAD (year 2019 vs. 2010; 0.90; 0.81-1.00,
Stroke, Volume 55, Issue Suppl_1 , Page A45-A45, February 1, 2024. Introduction:Telestroke enables timely and remote evaluation of patients with acute stroke syndromes. However, stroke mimics represent more than 30% of this population. To predict stroke mimic, TS had the highest AUC (68.3)
Stroke, Volume 55, Issue Suppl_1 , Page AWP49-AWP49, February 1, 2024. The Neuroscience Nurse Navigator Program [NNN-P], implemented December 2019, included SP who received Alteplase [IV-A] or Mechanical Thrombectomy [MT]. SP satisfaction [SP-S] assessed via paper tool changed to Press Ganey in 2021.Purpose:Evaluate
Stroke, Volume 56, Issue Suppl_1 , Page AWP104-AWP104, February 1, 2025. Background:Previous findings have shown high mobile stroke unit (MSU) call density scattered across a coverage area. Our MSU is operational from 0700-1900 and is dispatched for all 911 calls designated as probable or definite strokes.
Stroke, Volume 56, Issue Suppl_1 , Page AWP96-AWP96, February 1, 2025. Our MSU is operational from 0700-1900 and is dispatched for all 911 calls designated as probable or definite strokes. We retrospectively reviewed all MSU calls from June 2019 to December 2023. and included all confirmed stroke patients in this analysis.
Stroke, Volume 56, Issue Suppl_1 , Page ADP52-ADP52, February 1, 2025. Background:Physical activity is an effective modifiable behavior for preventing recurrent strokes. This study aims to determine the adherence to physical activity recommendations among stroke survivors in the United States. 62.3%; p<0.0001).
Stroke, Volume 55, Issue Suppl_1 , Page AWMP41-AWMP41, February 1, 2024. Introduction:High-quality prehospital care during initial assessment by EMS providers can affect downstream care for acute stroke patients. Stroke scale assessment was documented in 78% of cases, and blood glucose in 88%.
Stroke, Volume 56, Issue Suppl_1 , Page ATP139-ATP139, February 1, 2025. The stepped-wedge trial ran from May 2019 to January 2024 across three implementation waves. Findings provide a roadmap for healthcare systems implementing similar interventions, emphasizing leadership, coordinated care, and robust tracking for program success.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP34-AWMP34, February 1, 2025. Introduction:Pediatric stroke, while one of the top 10 causes of mortality among U.S. We also identified all out-of-hospital strokes admitted to CHOC (ICD-10 search of discharge diagnoses) and determined the proportion of strokes presenting via EMS.
Stroke, Ahead of Print. BACKGROUND:Timely intravenous thrombolysis and endovascular thrombectomy are the standard reperfusion treatments for large vessel occlusion stroke. hours of onset) and thrombectomy treatment from January 2019 to April 2023. hours of onset) and thrombectomy treatment from January 2019 to April 2023.
Stroke: Vascular and Interventional Neurology, Ahead of Print. BACKGROUNDEarly recognition of large‐vessel occlusion in acute ischemic stroke is pivotal to ensuring timely and effective treatment. However, current prehospital evaluation strategies largely rely on stroke scales that lack sensitivity and specificity.
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