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Novartis Reclaims Anthos, Reenters Factor XI Race

CardiacWire

Novartis spun out the testing and development of abelacimab and formed Anthos Therapeutics back in 2019. Novartis initially prioritized its treatments for heart failure and plaque-clogged arteries when it spun-off abelacimab but continued to monitor the Factor XI race, leading to its choice to take the baton back from Anthos.

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Elucid Commences International PRE-VUE CCT Registry Study

DAIC

This registry will aim to provide world-wide physicians the most accurate information on coronary plaque to improve cardiovascular risk prediction and support the selection of patient-specific treatment,” said Dr. De Cecco. The ultimate goal is to positively impact cardiovascular health globally with a reduction in cardiovascular events."

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TCFA : The stylish caps of Atherosclerotic plaques are getting disproportionate attention.

Dr. S. Venkatesan MD

Doctor, do you have any investigation to know how much the total plaque burden is in my coronary artery? I recently read in Forbes Sunday health supplement, It says ,it is better to know the thickness of the cap covering the plaque. to decode the histological, biochemical, pathological secrets within the atherosclerotic plaques.

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At What Age Should You Think About Assessing Your Risk For Heart Disease?

Dr. Paddy Barrett

Everyone starts with no plaque in the coronary arteries, but over a long enough time frame, everyone develops plaque in their coronary arteries. By age 80, almost everyone will have evidence of advanced plaque in their coronary arteries, as defined by a cardiac CT 1. Plaque accumulation happens in stages. You got it.

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ECG Blog #415 — The Cath showed NO Occlusion!

Ken Grauer, MD

I i llustrate the ECG finding of T-QRS-D below in Figure-3 , which I've excerpted from My Comment i n the November 14, 2019 post in Dr. Smith's ECG Blog. Non-obstructive coronary disease at the time cardiac cath is done does not necessarily imply there was no plaque rupture with thrombus. A picture is worth 1,000 words.

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Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

DAIC

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. A focused update to the 2019 NLA scientific statement on use of lipoprotein(a) in clinical practice.

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Concerning EKG with a Non-obstructive angiogram. What happened?

Dr. Smith's ECG Blog

The commonest causes of MINOCA include: atherosclerotic causes such as plaque rupture or erosion with spontaneous thrombolysis, and non-atherosclerotic causes such as coronary vasospasm (sometimes called variant angina or Prinzmetal's angina), coronary embolism or thrombosis, possibly microvascular dysfunction. It is not rare.

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