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Novartis Reclaims Anthos, Reenters Factor XI Race

CardiacWire

Novartis spun out the testing and development of abelacimab and formed Anthos Therapeutics back in 2019. Novartis initially prioritized its treatments for heart failure and plaque-clogged arteries when it spun-off abelacimab but continued to monitor the Factor XI race, leading to its choice to take the baton back from Anthos.

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TCFA : The stylish caps of Atherosclerotic plaques are getting disproportionate attention.

Dr. S. Venkatesan MD

Doctor, do you have any investigation to know how much the total plaque burden is in my coronary artery? I recently read in Forbes Sunday health supplement, It says ,it is better to know the thickness of the cap covering the plaque. to decode the histological, biochemical, pathological secrets within the atherosclerotic plaques.

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ECG Blog #415 — The Cath showed NO Occlusion!

Ken Grauer, MD

I i llustrate the ECG finding of T-QRS-D below in Figure-3 , which I've excerpted from My Comment i n the November 14, 2019 post in Dr. Smith's ECG Blog. Non-obstructive coronary disease at the time cardiac cath is done does not necessarily imply there was no plaque rupture with thrombus. A picture is worth 1,000 words.

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Roche's Lp(a) Gen.2 Molarity Assay Receives FDA Clearance

DAIC

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. A focused update to the 2019 NLA scientific statement on use of lipoprotein(a) in clinical practice.

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Concerning EKG with a Non-obstructive angiogram. What happened?

Dr. Smith's ECG Blog

The commonest causes of MINOCA include: atherosclerotic causes such as plaque rupture or erosion with spontaneous thrombolysis, and non-atherosclerotic causes such as coronary vasospasm (sometimes called variant angina or Prinzmetal's angina), coronary embolism or thrombosis, possibly microvascular dysfunction. It is not rare.

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Henry Ford Health Cardiologists Publish Case Series Study on Heart Valve Procedure

DAIC

IVL is a novel approach to lesion preparation of severely calcified plaques in coronary and peripheral vessels. The Henry Ford team performed its first IVL-enabled mitral valvuloplasty back in 2019 and completed its first published case study.

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What does the angiogram show? The Echo? The CT coronary angiogram? How do you explain this?

Dr. Smith's ECG Blog

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. Thus, intracoronary imaging modalities are crucial in this setting. From Gue at al.