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Systematic search conducted without language restrictions from December 1, 2019 to June 31, 2022 on PubMed, EMBASE, Web of Science, Cochrane library, ProQuest Coronavirus Research Database, COVID-19 Living Overview of the Evidence (L-OVE) subset of Episteminokos and the World Health Organization (WHO) Covid-19 databases.
Findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial were presented on the first day of the American Stroke Association’s International Stroke Conference, ISC 2024, being held through Feb. The study was looking for improvement in functional outcomes at 90 days. 9 Phoenix, AZ.
Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal.
The primary outcome was atherothrombotic major adverse cardiovascular events as a composite outcome of cardiovascular mortality, nonfatal stroke, and nonfatal myocardial infarction. Patients were propensity matched in a 1:1 ratio using a caliper distance of 0.2 without replacement.
7-9, and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health. 7-9, and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health. The meeting will be held in Phoenix, Feb. The meeting will be held in Phoenix, Feb.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP100-ATMP100, February 1, 2024. Introduction:Rising obesity rates and the increasing prevalence of stroke in the metabolically healthy obese (MHO) necessitate examining its association in younger (18-44 year) populations.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP98-ATMP98, February 1, 2024. Introduction:Functional outcomes after acute stroke (AS) are related to the initial neurological severity. We defined MNS as a score of ≤5 points on the National Institutes of Health Stroke Scale.
Stroke, Volume 55, Issue Suppl_1 , Page A13-A13, February 1, 2024. Elderly obese stroke survivors (> 65 years) having a recurrent acute ischemic stroke (AIS), with or without prior bariatric surgery (PBS), were identified using ICD-10 codes. Both groups (PBS vs. no PBS) were predominantly female (59.7% vs. 90.7%).
Stroke, Volume 55, Issue Suppl_1 , Page ATP120-ATP120, February 1, 2024. Background:Racial disparities in stroke prevalence and outcomes have been well documented in previous studies, but there is not sufficient data based on post-menopausal women. Demographics were analyzed after stratifying the population by race. Hispanic, 3.6%
Stroke, Volume 56, Issue Suppl_1 , Page AWP268-AWP268, February 1, 2025. Introduction:The overall composition of stroke subtype is typically stable within biogeographical groups. Whether the COVID-19 pandemic impacted stroke etiology is still being investigated, but most studies have been performed outside the United States.
Tricuspid Valve Repair Existing literature on national surgical outcomes of isolated tricuspid valve repair or replacement is based on data from over a decade ago and may not reflect current practice results. The majority require explant of the TAVR device and SAVR, which significantly increases the risk of operative mortality and stroke.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP73-ATMP73, February 1, 2024. We aim to better understand this risk and its impact on in-hospital outcomes over a longitudinal time period in a large population based sample.Methods:We analyzed the 2000-2019 National Inpatient Sample, selecting for aneurysmal SAH (aSAH).
Background Redo sternotomy aortic root surgery is technically demanding, and the evidence on outcomes is mostly from retrospective, small sample, single-centre studies. We report the trend, early clinical results and outcome predictors of redo aortic root replacement over 20 years in the United Kingdom.
Stroke, Volume 55, Issue Suppl_1 , Page ATP230-ATP230, February 1, 2024. Introduction:Atrial fibrillation (AF) and cancer are both independently associated with worse outcomes in patients with acute ischemic stroke. Few studies have evaluated the impact of AF on outcomes of cancer-related stroke.
Stroke, Volume 55, Issue Suppl_1 , Page ATP96-ATP96, February 1, 2024. Introduction:Recent studies in adults have reported an association between neighborhood-level deprivation, infarct volume and outcome. However, this is yet to be investigated in pediatric arterial ischemic stroke (AIS). years [IQR 1.0-12.7]). years [IQR 1.0-12.7]).
Stroke, Volume 55, Issue Suppl_1 , Page AWP203-AWP203, February 1, 2024. A total of 4353 patients who underwent endovascular treatment for acute ischemic stroke between January 2016 and December 2020 were included in the study. The primary outcome measure was good outcome at discharge, defined as a modified Rankin Scale score of 0-2.Results:Of
Stroke, Volume 56, Issue Suppl_1 , Page AWP143-AWP143, February 1, 2025. Patient-reported outcome measures (PROMs) provides a means to assess these symptoms, capturing aspects of health often missed by clinician-reported assessments. The median mRS of both CVT and ischemic stroke patients was 1 [IQR 0,1]. female, 74.7%
Stroke, Volume 56, Issue Suppl_1 , Page ATP136-ATP136, February 1, 2025. Once these post-stroke patients have been identified, they are given a personalized monitoring plan depending on the individuals risk factors, the personalized care and rehabilitation plans are tracked and followed.
Stroke, Volume 56, Issue Suppl_1 , Page AHUP8-AHUP8, February 1, 2025. The characteristics and outcomes of the patients with or without safety-net features treated at SNHs vs non-SNHs were compared after adjusting for patient and hospital characteristics. 1.19, p<0.001) and composite outcome (aOR 1.17, 95% CI 1.14-1.19),
Stroke, Volume 56, Issue Suppl_1 , Page ATP132-ATP132, February 1, 2025. The characteristics and outcomes of the patients with or without safety-net features treated at SNHs vs non-SNHs were compared after adjusting for patient and hospital characteristics. 1.19, p<0.001) and composite outcome (aOR 1.17, 95% CI 1.14-1.19),
Stroke, Volume 55, Issue Suppl_1 , Page AWP274-AWP274, February 1, 2024. Demographics, comorbidities, and outcomes were identified. Functional outcome was categorized in Excellent, Good and Poor. The Hispanic patients had more likelihood to have an excellent outcome (P=0.003).Conclusions:Approximately days, 95%CI:3.03-4.07),
Stroke, Volume 55, Issue Suppl_1 , Page AWP126-AWP126, February 1, 2024. Introduction:The rapid advancement of artificial intelligence (AI) technologies holds promise for improving healthcare outcomes. Methods:Data for this study were obtained from the Get with the Guidelines Stroke database.
Stroke, Volume 55, Issue Suppl_1 , Page AWP10-AWP10, February 1, 2024. Introduction:While observational data suggest that dexmedetomidine may have neuroprotective effects on ischemic brain, its clinical use in acute ischemic stroke is limited due to concerns about cerebral vasoconstriction. vs. 28.8%; p=0.24).
Stroke, Volume 56, Issue Suppl_1 , Page AWP88-AWP88, February 1, 2025. Background:The effect of renal dysfunction on early infarct growth rate (IGR) in anterior circulation large vessel occlusion (ACLVO) stroke is not well studied. mg/dL, p < 0.05) and lower median eGFR (66.2 mL/min/1.73m2, p < 0.05).
Data on major cardiovascular events (MACE; mortality, myocardial infarction, stroke, heart failure) through December 2021 were obtained from national registries. Trend analyses for the years 2010–2019 revealed improved one-year MACE in patients with diabetes and CAD (year 2019 vs. 2010; 0.90; 0.81-1.00,
Stroke, Volume 55, Issue Suppl_1 , Page AWP22-AWP22, February 1, 2024. Introduction:Tenecteplase (TNK) is increasingly being utilized for IV thrombolysis in acute ischemic stroke, including for patients with large vessel occlusion (LVO) prior to transfer to an endovascular thrombectomy (EVT) capable center (TCC). TNK vs. 48.4%
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. A prior published analysis of national trends after one year in mechanical thrombectomy use and outcomes for stroke before and after publication of the 2015 US guideline update showed improved functional outcomes and lower peri‐procedural mortality.
Stroke, Ahead of Print. BACKGROUND:Timely intravenous thrombolysis and endovascular thrombectomy are the standard reperfusion treatments for large vessel occlusion stroke. hours of onset) and thrombectomy treatment from January 2019 to April 2023. hours of onset) and thrombectomy treatment from January 2019 to April 2023.
Stroke, Volume 56, Issue Suppl_1 , Page A122-A122, February 1, 2025. Introduction:Standardized stroke response protocols have been shown to reduce Door to Puncture (DTP) times for Acute Ischemic Strokes (AIS), potentially improving functional outcomes and reducing mortality. This reduction time is equivalent to 22.8
Stroke, Volume 55, Issue Suppl_1 , Page ATMP21-ATMP21, February 1, 2024. Background:Medical comorbidities and stroke risk factors explain only a proportion of stroke incidence and outcomes in different populations. The primary outcome measure was discharge to home.
Stroke, Volume 56, Issue Suppl_1 , Page ATP126-ATP126, February 1, 2025. Although these changes are significant for the stroke survivor, they are consequential for the caregiver of the stroke patient as well. Conclusion:Worse stroke patient outcome has a negative association with caregiver mental health and caregiver strain.
BackgroundReasons for racial disparities in the use and outcomes of endovascular treatment (ET) are not known. Using unadjusted and adjusted multilevel logistic models, we examined associations between measures of segregation and outcomes of discharge home, inpatient mortality, and 30‐day mortality.
Stroke, Volume 56, Issue 1 , Page 74-83, January 1, 2025. BACKGROUND:Although the presence of amyloid deposits is associated with a more severe cognitive status in patients with stroke at baseline, its influence on the subsequent cognitive outcome has not been extensively assessed. 95% CI, 2.536.9];P=0.001), 95% CI, 2.536.9];P=0.001),
BackgroundPrevious clinical trials found improved outcome of thrombolytic treatment in patients with ischemic wake‐up stroke (WUS) selected by advanced imaging techniques. Thrombolytic treatment in WUS versus known‐onset stroke was compared in 730 patients (365 matched pairs). 1.74];P=0.050). versus 59.5%; OR, 0.69 [95% CI, 0.52–0.93];P=0.013),
Stroke, Volume 55, Issue Suppl_1 , Page AWP263-AWP263, February 1, 2024. The concentration of equol was measured using liquid chromatography-mass spectrometry.Results:Eighty-five patients with stroke (43.5%) and 50 healthy subjects (48.5%) were equol producers (p=0.32). p=0.04) among patients with ischemic stroke.
Stroke, Volume 56, Issue Suppl_1 , Page ATP270-ATP270, February 1, 2025. Introduction:Syphilis is associated with increased risk of cerebrovascular disease and acute stroke; stroke may even be the initial clinical manifestation of syphilis (Images 1 and 2). between 2016-2019, but then dropped to 1.02% in 2020.
Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. Of the ischemic strokes, 22% were small-vessel occlusion, 8% large artery atherosclerosis, 21% cardioembolic, and 49% cryptogenic/other determined etiology.
Stroke, Volume 56, Issue Suppl_1 , Page ATP257-ATP257, February 1, 2025. Trials with functional outcomes measured at 3 months were included. Data extracted included year of publication, estimated and actual sample sizes, observed outcomes, and statistical methods used. 7 studies met or almost met their estimated sample size.14
Stroke, Volume 55, Issue Suppl_1 , Page AWMP51-AWMP51, February 1, 2024. Background:Medical comorbidities and stroke risk factors explain only a proportion of stroke incidence and outcomes in different populations. The primary outcome measure was discharge to home.
BackgroundPatients with ischemic stroke and concomitant COVID‐19 infection have worse outcomes than those without this infection, but the impact of COVID‐19 on hemorrhagic stroke remains unclear. We aimed to assess if COVID‐19 worsens outcomes in intracerebral hemorrhage (ICH).Methods
Stroke: Vascular and Interventional Neurology, Ahead of Print. BACKGROUNDEarly recognition of large‐vessel occlusion in acute ischemic stroke is pivotal to ensuring timely and effective treatment. However, current prehospital evaluation strategies largely rely on stroke scales that lack sensitivity and specificity.
Stroke, Volume 55, Issue Suppl_1 , Page AWP17-AWP17, February 1, 2024. Introduction:The launch of AHA’s Target: Stroke Phase III in 2019 challenged stroke centers to achieve DTN times ≤ 30 min of arrival to ≥ 50% of AIS patients treated with IV thrombolytics.
Stroke, Volume 55, Issue Suppl_1 , Page ATP265-ATP265, February 1, 2024. Introduction:Recent trials have shown the benefit of PFO closure in recurrent stroke prevention. There is no standardized practice to dictate appropriate AC/AP therapy in the setting of stroke secondary to PFO prior to closure.
Stroke, Volume 55, Issue Suppl_1 , Page AWMP106-AWMP106, February 1, 2024. Background:Medical comorbidities and stroke risk factors only explain a proportion of stroke incidence and outcomes in different populations. Social determinants of health(SDOH)have been associated with incident stroke.
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