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Expert Perspective: The Obesity Paradox with Salvatore Carbone, PhD

Cardiometabolic Health Congress

There are significant data that show that if you have obesity, you have a high risk of developing coronary heart disease, heart failure, type 2 diabetes (T2D) or risk factors such as hypertension and dyslipidemia. [1] These individuals tend to have a better prognosis when compared to both individuals with normal weight (BMI of 18.5

Obesity 52
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Abstract WP319: Reliability and validity of self-reported risk factors for stroke and dementia

Stroke Journal

Reliability of self-reported risk factors was high in overweight (F1 0.81) and diabetes (F1 0.71), moderate in hearing impairment (F1 0.59) and hypertension (F1 0.56) and low in hypercholesterolemia (F1 0.49) and kidney disease (F1 0.25).

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Attenuated kidney oxidative metabolism in young adults with type 1 diabetes

Journal of Clinical Investigation - Cardiology

Pseudotime progression associated with higher HbA1c, BMI, and GBM, and lower insulin sensitivity and cortical oxidative metabolism.CONCLUSION These early structural and metabolic changes in T1D kidneys may precede clinical DKD.TRIAL REGISTRATION ClinicalTrials.gov NCT04074668.FUNDING