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3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heartattack or myocardial infarction (MI), stroke, and cardiovascular (CV) death.4 milligrams per liter (mg/L) are linked to increased risk of heartattacks or risk of a repeat heartattack.23 4 In the U.S.
Reduction in admissions for stroke recurrence or related to stroke, (heartattack, angina, peripheral embolism, etc.): Stroke, 30days: -100%; Related to stroke, (365d: -47,7%; 30d: -57,0%).
LDL floats around in the blood stream and is thought to incrementally accumulate on blood vessels in the body, ultimately increasing the risk of heartattacks and strokes. The positive results described were driven almost entirely by fewer heartattacks, and fewer revascularization procedures in the evolucumab arm.
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