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An explainable machine learning approach using contemporary UNOS data to identify patients who fail to bridge to heart transplantation

Frontiers in Cardiovascular Medicine

BackgroundThe use of Intra-aortic Balloon Pump (IABP) and Impella devices as a bridge to heart transplantation (HTx) has increased significantly in recent times. We used the eXtreme Gradient Boosting (XGBoost) algorithm to build and validate ML models.

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Emergency Department Use and Hospital Mortality Among Heart Transplant Recipients in the United States

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundAnnual heart transplant (HT) volumes have increased, as have post‐HT outpatient care needs. HT volumes and HT‐related ED visits increased from 2009 to 2018. Multivariable logistic regression was used to predict outcomes of hospital admission and death.

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Waitlist Outcomes in Candidates With Rare Causes of Heart Failure After Implementation of the 2018 French Heart Allocation Scheme

Circulation: Heart Failure

Circulation: Heart Failure, Ahead of Print. BACKGROUND:In 2018, an algorithm-based allocation system for heart transplantation (HT) was implemented in France.

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Impact of Heart Transplant Allocation Changes on Waitlist Mortality and Clinical Practice in Pediatric and Adult Patients With Congenital Heart Disease and Cardiomyopathy

Circulation

BACKGROUND:The United Network of Organ Sharing made changes to the priority for allocation of hearts for transplantation (HT) in 2016 for pediatric patients and 2018 for adult patients. Circulation, Ahead of Print.

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Lantheus Announces the FDA Approval of DEFINITY as Ultrasound Enhancing Agent for Use in Certain Pediatric Cardiovascular Patients

DAIC

Food and Drug Adminstration (FDA) has approved DEFINITY (Perflutren Lipid Microsphere) as an ultrasound enhancing agent for use in pediatric patients with suboptimal echocardiograms, including those who have undergone heart transplant, or have Kawasaki disease or a congenital cardiovascular anomaly. All rights reserved. 5 Kutty, S.,

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Early left atrial venting versus conventional treatment for left ventricular decompression during venoarterial extracorporeal membrane oxygenation support: The EVOLVE?ECMO randomized clinical trial

European Journal of Heart Failure

CV, cardiovascular; HT, heart transplantation; ICU, intensive care unit; LVAD, left ventricular assist device. Methods and results Between December 2018 and August 2022, 60 patients at two institutions were randomized in a 1:1 ratio to receive early ( n  = 30) or conventional ( n  = 30) LV unloading strategies.

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Clinical Outcomes for Heart‐Alone and Multiorgan Transplant Under the New Heart Allocation Policy Era

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundIn October 2018, a new heart transplant allocation policy was implemented in the United States to address inequalities.