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The Potential Risks of GLP-1s

CardiacWire

To tackle this problem, researchers compared Veterans Affairs data on 2 million T2D patients (2017-2023) taking either GLP-1s , DPP4is, SGLT2is, or usual care antihyperglycemics over a 3.68 Starting with the good news, GLP-1s lowered risks for 42 health outcomes while increasing risks for 19 outcomes. year follow-up.

Obesity 59
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Recurrent Stroke Prediction by Applying a Stroke Polygenic Risk Score in the Japanese Population

Stroke Journal

Stroke, Ahead of Print. BACKGROUND:Recently, various polygenic risk score (PRS)based methods were developed to improve stroke prediction. However, current PRSs (including cross-ancestry PRS) poorly predict recurrent stroke. In particular, it predicted an increased risk of recurrence among stroke patients without hypertension.

Stroke 75
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Time Window for Induced Hypertension in Acute Small Vessel Occlusive Stroke With Early Neurological Deterioration

Stroke Journal

Stroke, Ahead of Print. BACKGROUND:Therapeutic-induced hypertension treatment (iHTN) is helpful for alleviating early neurological deterioration (END) in acute small vessel occlusive stroke. The mean age was 65.1 (±12.0) years, and 61.0% The efficacy of iHTN may be limited to induction within the first 3 hours of END.

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Nerve Stimulation Plus Intense Rehab May Improve Arm and Hand Function After Stroke

DAIC

7-9, and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health. 7-9, and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health. The meeting will be held in Phoenix, Feb. The meeting will be held in Phoenix, Feb.

Stroke 98
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The Society of Thoracic Surgeons Launches New Valve Surgery Risk Calculators

DAIC

Tricuspid Valve Repair Existing literature on national surgical outcomes of isolated tricuspid valve repair or replacement is based on data from over a decade ago and may not reflect current practice results. Analysis of 13,587 patients undergoing isolated tricuspid valve surgery from 2017 to 2023 revealed a 5.5%

TAVR 111
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Intravenous Thrombolysis Before Thrombectomy Improves Functional Outcome After Stroke Independent of Reperfusion Grade

Journal of the American Heart Association

In our study population of 1000 thrombectomy‐eligible patients (513 women; median age, 77 years [interquartile range, 67–84]), IVT emerged as a predictor of favorable functional outcome (modified Rankin Scale score, 0–2) independent of modified mTICI score (adjusted odds ratio, 0.49 [95% CI, 0.32–0.75];P=0.001). 0.75];P=0.001).

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In-hospital outcomes predictors and trends of redo sternotomy aortic root replacements: insights from a UK registry analysis

Frontiers in Cardiovascular Medicine

Background Redo sternotomy aortic root surgery is technically demanding, and the evidence on outcomes is mostly from retrospective, small sample, single-centre studies. We report the trend, early clinical results and outcome predictors of redo aortic root replacement over 20 years in the United Kingdom.