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Update on Diagnosis and Management of Kawasaki Disease: A Scientific Statement From the American Heart Association

Circulation

This update summarizes relevant clinical data published since the 2017 American Heart Association scientific statement on KD related to diagnosis, cardiac imaging in acute KD treatment, and long-term management. Recent data have advanced the understanding of safety and dosing for several anti-inflammatory therapies in KD.

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HeartFlow Announces Revolutionary Five-Year Data Demonstrating a 63 Percent Mortality Reduction with FFRCT-Guided Care in PAD Patients

DAIC

6 This novel study marks a significant milestone in the field, evaluating the effectiveness of FFR CT in detecting ischemia-producing coronary stenosis in patients with severe PAD. Diagnosis and treatment of ischemia-producing coronary stenoses improves 5-year survival of patients undergoing major vascular surgery.” 2024, [link].

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Results of CERTAIN Study Demonstrate Prominent Effects of Cleerly Products on Changing Clinical Management for Patients Suspected of Coronary Artery Disease

DAIC

2-7 Through its FDA-cleared solutions driven by artificial intelligence, Cleerly, founded in 2017, supports comprehensive phenotyping of coronary artery disease, as determined from advanced non-invasive CT imaging. High Diagnostic Accuracy Of AI-Ischemia in Comparison To PET, FFR-CT, SPECT, and Invasive FFR: A PACIFIC Sub-Study.

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Elucid Commences International PRE-VUE CCT Registry Study

DAIC

The company is also pursuing an indication for non-invasive measurement of fractional flow reserve (FFR CT ), uniquely derived from its plaque algorithm, to measure coronary blockages and the extent of ischemia. 2017 23, April 2020; Available from: [link]. Cardiovasc. 6 (3) (2019).

Plaque 105
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Does this T wave pattern mean anything?

Dr. Smith's ECG Blog

2017 Oct 1;177(10):1520-1522. Alternation in ST segment appearance ( or in the amount of ST elevation or depression ) — is often linked to ischemia. J Am Coll Cardiol. 2006 Jan 17;47(2):269-81. doi: 10.1016/j.jacc.2005.08.066. 2005.08.066. Epub 2006 Jan 4. PMID: 16412847. Moore PK, Raffel KE, Whitman IR. JAMA Intern Med. 2017.3191.

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An elderly male with acute altered mental status and huge ST Elevation

Dr. Smith's ECG Blog

or basilar ischemia. 2017 Sep-Oct;50(5):561-569. Epub 2017 Apr 19. CTA head and neck were obtained and showed no evidence of intracranial hemorrhage, large vessel occlusion stroke (what a helpful and apt name for an acute arterial occlusion paradigm, by the way.), EKG on arrival to the ED is shown below: What do you think?

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What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

There is no definite evidence of acute ischemia. (ie, Simply stated — t he patient was having recurrent PMVT without Q Tc prolongation, and without evidence of ongoing transmural ischemia. ( Some residual ischemia in the infarct border might still be present. Both episodes are initiated by an "R-on-T" phenomenon.