2017, Circulation and Stenosis - Cardiovascular Update

Cerebral Hemodynamic Impairment and Cognitive Dysfunction in APOE4 Carriers With Asymptomatic Carotid Artery Stenosis/Occlusion

Journal of the American Heart Association

MARCH 13, 2025

BackgroundOur previous preclinical study demonstrated thatAPOE4targeted replacement mice exhibit more severe cerebral hypoperfusion and cognitive impairment thanAPOE3targeted replacement mice with carotid artery stenosis due to neurovascular dysfunction.

Stenosis

Stenosis Risk Factors Circulation

Update on Diagnosis and Management of Kawasaki Disease: A Scientific Statement From the American Heart Association

Circulation

NOVEMBER 13, 2024

Circulation, Ahead of Print. This update summarizes relevant clinical data published since the 2017 American Heart Association scientific statement on KD related to diagnosis, cardiac imaging in acute KD treatment, and long-term management.

Aneurysm

Aneurysm Myocardial Infarction Cardiovascular Imaging Ischemia

HeartFlow Announces Revolutionary Five-Year Data Demonstrating a 63 Percent Mortality Reduction with FFRCT-Guided Care in PAD Patients

DAIC

MAY 8, 2024

6 This novel study marks a significant milestone in the field, evaluating the effectiveness of FFR CT in detecting ischemia-producing coronary stenosis in patients with severe PAD. The 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European Society for Vascular Surgery (ESVS).”

Coronary Artery Disease

Coronary Artery Disease Chest Pain Ischemia Myocardial Infarction

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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Abstract 4135852: Safety and Post-operative Complications of Endovascular Versus Surgical Versus Follow-up and Medical Treatment for Patients with Vertebrobasilar Artery Stenosis: Propensity Score Weighting and a Machine Learning Driven Analysis

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4135852-A4135852, November 12, 2024. Background:Vertebrobasilar artery stenosis (VBAS) can cause posterior circulation strokes (PCS). Optimal management is controversial, with options including medical therapy (MT), endovascular stenting (ES), and surgical revascularization (SR).

Stenosis

Stenosis Inpatient Stents Stent

Abstract TMP69: Impaired Cognitive Function and Cerebral Hemodynamics Associated With APOE4 in Asymptomatic Carotid Artery Stenosis/Occlusion

Stroke Journal

FEBRUARY 1, 2024

However, it has not been clinically investigated in patients with asymptomatic CASO.Methods:A cross-sectional observational study was conducted between January 2017 and March 2022. We reportedAPOE4induces neurovascular dysfunction and cognitive impairment in a mouse model of CASO.

Stenosis

Stenosis Risk Factors Circulation Stroke

Atrial dilatation in Atrial fibrillation : A query with multiple twists!

Dr. S. Venkatesan MD

APRIL 28, 2024

Spatial relationship of sites for atrial fibrillation drivers and atrial tachycardia in patients with both arrhythmias July 2017 International Journal of Cardiology 248(3) AF begets AF. Pierre Jaïs Circulation 2000 ) When such flutters transform into fibrillation, how does the spillover of signals occur to the contralateral atrium?

Atrial Fibrillation

Atrial Fibrillation Bicuspid/Mitral Pulmonary Ablation

What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

JULY 21, 2024

Angiography : LMCA — 90-99% osteal stenosis. LCx — 50-69% stenosis of the 1st marginal branch; with 100% distal LCx occlusion. In this study — Procainamide was superior to Amiodarone for terminating monomorphic VT, as well as having fewer adverse effects than Amiodarone ( Ortiz et al — Eur Heart J 1;38 (17): 1329-1335, 2017 ).

Arrhythmia

Arrhythmia Cardiogenic Shock Bradycardia Defibrillator

Prevalence of Systemic Hypertension and the Effects of Cerebral Revascularization in Patients With Moyamoya Disease

Stroke: Vascular and Interventional Neurology

MARCH 6, 2024

BACKGROUNDHypertension is often codiagnosed in patients with moyamoya disease (MMD), a progressive intracranial steno‐occlusive vasculopathy; this has principally been attributed to renal artery stenosis (up to 10%). Blood pressure measurements and antihypertensive agent use were recorded pre‐ and postoperatively. months in adults (33.8±14.9

Hypertension

Hypertension Blood Pressure Pediatrics Kidney Disease

Concomitant Left Atrial Appendage Occlusion and Transcatheter Aortic Valve Replacement Among Patients with Atrial Fibrillation

Circulation

OCTOBER 23, 2023

Circulation, Ahead of Print. The primary non-inferiority endpoint was all-cause mortality, stroke, and major bleeding at 2-years between the two strategies.Results: The study enrolled 349 patients, 177 TAVR+LAAO and 172 TAVR+medical therapy, between December-2017 and November-2020 at 34 US centers. and HAS-BLED score was 3.0.

Aortic valve

Aortic valve Atrial Fibrillation TAVR Aortic

Why You Need To Measure apoB To Assess Your Cardiovascular Risk

Dr. Paddy Barrett

NOVEMBER 7, 2023

In this case, the only lipid particles remaining in circulation are usually LDL and Lp(a) particles. LDL cholesterol, when measured in the context of diabetes, metabolic syndrome or insulin resistance, is not an accurate reflection of the number of apoB particles in circulation. 2017 Aug 21;38(32):2459-2472. Eur Heart J.

Cholesterol

Cholesterol Atherosclerosis Stenosis Aortic

What Lies Beneath

EMS 12-Lead

AUGUST 22, 2022

The coronary angiogram revealed no critical stenosis, or acute plaque ulceration. Circulation, Vol 137, No 11, 1192-94. Circulation, Vol 139, No 16, 1974-76. Indeed, bedside Echocardiogram revealed severe left ventricular impairment of Takotsubo cardiomyopathy. Furthermore, pertinent electrolyte values (e.g. Saini, A.,

Tachycardia

Tachycardia Cardiomyopathy Electrophysiology ICU

Published Research

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Adult Cardiac Surgery Database Lead Author Title Publication Date Jacob Raphael Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis The Annals of Thoracic Surgery January 2024 Joseph Sabik Multi-Arterial versus Single-Arterial Coronary Surgery: Ten Year Follow-up of One Million (..)

Research

Research Coronary Artery Bypass Graft Aortic valve Congenital

Published Research

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Institutional Coronary Artery Bypass Case Volumes and Outcomes European Journal of Heart Failure October 2023 Makoto Mori 1 Robotic Mitral Valve Repair for Degenerative Mitral Regurgitation The Annals of Thoracic Surgery August 2023 Carlos Diaz-Castrillion 2 Volume-Failure to Rescue Relationship in Acute Type A Aortic Dissections: An Analysis of The (..)

Research

Research Coronary Artery Bypass Graft Aortic valve Congenital

Abstract TP225: Larger Basilar Arterial Diameters Correlate with Reduced Blood Flow Velocities in Ischemic Stroke Patients

Stroke Journal

JANUARY 30, 2025

Subgroup analysis excluding cases with BA stenosis and fetal posterior cerebral artery (fPCA) was also performed.Results:Among 211 ischemic stroke patients, 44 had vessel imaging and TCD. The mean age was 64 13 years, 66% were male, 36% had posterior circulation stroke, 11.4%

Stroke

Stroke Strokes Stenosis Ischemia

Prevalence of High-Risk CTA-Based Carotid Plaque-RADS Subtypes in Patients With Embolic Stroke of Undetermined Source

Stroke Journal

JANUARY 24, 2025

With the widespread use of CTA for stroke evaluation, a CTA-based Plaque-RADS would be valuable for generalizability.METHODS:A retrospective observational cross-sectional study was conducted at a single integrated health system comprised of 3 hospitals with a comprehensive stroke center between October 1, 2015, and April 1, 2017.

Plaque

Plaque Embolism Stroke Strokes

Emergency Department Syncope Workup: After H and P, ECG is the Only Test Required for Every Patient.

Dr. Smith's ECG Blog

APRIL 8, 2015

Aortic Dissection, Valvular (especially Aortic Stenosis), Tamponade. heart auscultation (aortic stenosis); c. Of the 67 patients who underwent targeted tests, suspected diagnoses were confirmed in 49 (73%) patients: aortic stenosis (n = 8, 1%), pulmonary embolism (n = 8, 1%), seizures/stroke (n = 30, 5%), and other diseases (n = 3).

Arrhythmia

Arrhythmia Outcomes Chest Pain Risk Factors

Long-Term Prognostic Implications of Non-Culprit Lesions in Patients Presenting With an Acute Myocardial Infarction: Is It the Angiographic Stenosis Severity or the Underlying High-Risk Morphology?

Circulation

JANUARY 31, 2025

Circulation, Ahead of Print. BACKGROUND:Patients with acute myocardial infarction and angiographically obstructive non-culprit lesions are at high risk for recurrent major adverse cardiac events (MACEs). Patients were followed for up to 5 years (median 4.1 interquartile range: 3.05.0]

Myocardial Infarction

Myocardial Infarction Stenosis Circulation

Cerebral Hemodynamic Impairment and Cognitive Dysfunction in APOE4 Carriers With Asymptomatic Carotid Artery Stenosis/Occlusion

Update on Diagnosis and Management of Kawasaki Disease: A Scientific Statement From the American Heart Association

HeartFlow Announces Revolutionary Five-Year Data Demonstrating a 63 Percent Mortality Reduction with FFRCT-Guided Care in PAD Patients

Webinars

Abstract 4135852: Safety and Post-operative Complications of Endovascular Versus Surgical Versus Follow-up and Medical Treatment for Patients with Vertebrobasilar Artery Stenosis: Propensity Score Weighting and a Machine Learning Driven Analysis

Abstract TMP69: Impaired Cognitive Function and Cerebral Hemodynamics Associated With APOE4 in Asymptomatic Carotid Artery Stenosis/Occlusion

Atrial dilatation in Atrial fibrillation : A query with multiple twists!

What are treatment options for this rhythm, when all else fails?

Prevalence of Systemic Hypertension and the Effects of Cerebral Revascularization in Patients With Moyamoya Disease

Concomitant Left Atrial Appendage Occlusion and Transcatheter Aortic Valve Replacement Among Patients with Atrial Fibrillation

Why You Need To Measure apoB To Assess Your Cardiovascular Risk

What Lies Beneath

Published Research

Published Research

Abstract TP225: Larger Basilar Arterial Diameters Correlate with Reduced Blood Flow Velocities in Ischemic Stroke Patients

Prevalence of High-Risk CTA-Based Carotid Plaque-RADS Subtypes in Patients With Embolic Stroke of Undetermined Source

Emergency Department Syncope Workup: After H and P, ECG is the Only Test Required for Every Patient.

Long-Term Prognostic Implications of Non-Culprit Lesions in Patients Presenting With an Acute Myocardial Infarction: Is It the Angiographic Stenosis Severity or the Underlying High-Risk Morphology?

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