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Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. BACKGROUND:Differences in the quality of hospitals where Black and White patients receive coronary artery bypass grafting (CABG) surgery have been documented.
Over time, the build-up of these proteins causes the heart muscle to stiffen, eventually leading to heart failure, which can have dire outcomes if not found early. Circulation. Cardiac amyloidosis is a heterogeneous disease that results from the accumulation of abnormal proteins within the heart, impairing its ability to pump blood.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. BACKGROUND:The ongoing TANGO2 (Telephone Assisted CPR. Inclusion criteria were witnessed event, bystander on the scene with previous CPR training, age above 18 years of age, and no signs of trauma, pregnancy, or intoxication.
In our study population of 1000 thrombectomy‐eligible patients (513 women; median age, 77 years [interquartile range, 67–84]), IVT emerged as a predictor of favorable functional outcome (modified Rankin Scale score, 0–2) independent of modified mTICI score (adjusted odds ratio, 0.49 [95% CI, 0.32–0.75];P=0.001). 0.75];P=0.001).
Circulation: Cardiovascular Interventions, Ahead of Print. We compared outcomes between the conventional implantation method using the 3-cusps view (3 cusps without ICE group), the recent method using cusp-overlap view (cusp overlap without ICE group), and our novel method using ICE (cusp overlap with ICE group).RESULTS:Of
Introduction:Animal research suggests that HDL cholesterol (HDL-C) ameliorates reperfusion injury, a phenomenon that worsens clinical outcome following recanalization therapy for ischemic stroke.Hypothesis:We hypothesized that higher HDL-C levels have a guarding effect against cerebral reperfusion injury in human stroke survivors treated with thrombectomy.Methods:We (..)
We performed sensitivity analysis using propensity score matching.Results:In our study population of 1000 thrombectomy-eligible patients (513 females, median age 77 [67-84, interquartile range]) IVT emerged as predictor of favorable functional outcome (mRS 0-2) independent of mTICI (adjusted OR 0.49; 95% CI [0.32;0.75]; p=0.001).
Background:Early prediction of functional outcome after rtPA helps clinicians in prognostic conversations with stroke patients and their families. modified Rankin Scale (mRS) at one month, classified into good (mRS 2) and poor (mRS 5) outcomes was noted. 12% of the cohort (n=34) had posterior circulation stroke. 0.90) outcomes.
Introduction:Challenging anatomy and tortuous vessels have been associated with poor outcomes in endovasculat treatment (EVT) of stroke. Stroke, Volume 56, Issue Suppl_1 , Page ADP40-ADP40, February 1, 2025.
Circulation, Volume 150, Issue Suppl_1 , Page A4135852-A4135852, November 12, 2024. Background:Vertebrobasilar artery stenosis (VBAS) can cause posterior circulation strokes (PCS). Optimal management is controversial, with options including medical therapy (MT), endovascular stenting (ES), and surgical revascularization (SR).
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Background:Type 2 myocardial infarction (T2MI) and type 1 myocardial infarction (T1MI) differ with respect to demographics, comorbidities, treatments, and clinical outcomes. T1MI and 53.5% T2MI; mean age, 79±10.3 years; 47% female).
Circulation: Cardiovascular Interventions, Ahead of Print. kg at all Congenital Cardiac Catheterization Project on Outcomes participating centers. kg at all Congenital Cardiac Catheterization Project on Outcomes participating centers.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. The primary outcome was the percentage of patients receiving appropriate prophylaxis (high-risk patients with pharmacological thromboprophylaxis plus low-risk patients without prophylaxis) within 48 hours of hospitalization.
Collateral status is a well-documented marker of reperfusion and mortality in patients with large vessel occlusion (LVO) anterior circulation strokes, which account for approximately one-third of AIS. Methods:We retrospectively evaluated AIS patients treated at our institution between January 2017 and January 2023.
Circulation, Volume 150, Issue Suppl_1 , Page A4141522-A4141522, November 12, 2024. The clinical correlation between the methylation of the vtRNA 2-1 promoter and postoperative outcomes in obese patients remains unclear. However, some patients do not experience the desired weight loss.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. We used linear regression to examine the relationships between a new hypertension diagnosis (primary independent variable) and differences in the change in study outcomes from baseline to 6-month.Results:Mean age of study participants was 58.3
Circulation, Volume 150, Issue Suppl_1 , Page A4141279-A4141279, November 12, 2024. Background:Slow flow phenomenon is impaired coronary flow during percutaneous coronary intervention (PCI) in absence of mechanical obstruction, and it is associated with deteriorated outcome.
We aimed to assess whether endovascular treatment (EVT) compared with standard medical care was associated with improved functional outcomes in patients with acute symptomatic isolated intracranial ICA occlusion without involvement of the middle or anterior cerebral artery, that is, ICA‐I occlusion. versus 14.4%;P<0.001),
Large vessel occlusion (LVO) is found in 10% of MSS cases and predicts poor neurological outcomes. Descriptive statistics were applied to demographic, clinical, radiographic, and neurological outcomes data, including early neurological deterioration (END) (NIHSS gain 3+).Results:Ninety years old, with 58.8% black, and 16.2%
Circulation, Volume 150, Issue Suppl_1 , Page A4139285-A4139285, November 12, 2024. Awareness of symptoms is vital for early recognition and prompt treatment, which can significantly improve health outcomes. Introduction:Stroke and Myocardial Infarction (MI) are the leading causes of death in the United States.
Circulation, Volume 150, Issue Suppl_1 , Page A4119300-A4119300, November 12, 2024. The value of the CHA2DS2-VASc score in predicting adverse outcomes during pregnancy was also assessed.Study Design:The National Inpatient Sample (NIS) database was queried to identify pregnancy-related hospitalizations from 2008 to 2017.
Circulation: Cardiovascular Interventions, Volume 18, Issue 3 , Page e014899, March 1, 2025. High-quality, contemporary, multicenter data regarding clinical outcomes after PCI is scarce and poses a barrier to clinical decision-making for surgically ineligible patients.
Our goal is to deliver the best possible outcomes for patients; this study will help us understand the potential role of AVIM therapy in treating hypertension, a major source of cardiovascular illness and a comorbidity in more than 70% of patients receiving pacing therapy.” Circulation. 2017; 135: e146. Kowal, M.D.,
Circulation, Ahead of Print. Cohorts were grouped into preallocation and postallocation change eras: pediatric patients from January 1, 2011, to March 21, 2016, and January 1, 2017, to December 31, 2021; and adult patients from January 1, 2015, to October 17, 2018, and January 1, 2019, to December 31, 2021.
They shocked him twice before return of spontaneous circulation. This is a critically important determination because of the 2017 AHA/ACC/HRS Guidelines for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death. His daughter immediately started CPR and another family member called EMS.
While radiologic collateral status is a known correlate of reperfusion and mortality in AIS patients with large vessel occlusions (LVOs) of the anterior circulation, whether this imaging marker is associated with patient functional status following EVT is unclear. A low modified Rankin score (mRS) indicating good functional outcomes (i.e.,
Carbone: A study recently published in the Journal of the American College of Cardiology looked at the effect of physical activity and sedentary behaviors in a very large number of patients,13 and we have reviewed this topic in a recent review published on Circulation Research. [14] Circulation Research 118.11 (2016): 1752-1770.
5 Over my career as a cardiovascular surgeon, as well as an immunologist, I have witnessed how current treatments for ASCVD have led to considerable improvements in outcomes, yet many patients remain vulnerable to life-threatening cardiac events.1,6 2019 Sep 10;140(11):e649-e650] [published correction appears in Circulation.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Incident HF hospitalizations or HF-related deaths through 2017 were adjudicated. Background:Heart failure (HF) affects >6 million US adults, with recent increases in HF hospitalizations. were Black adults, 54.9% females, and 18.8% had diabetes.
Circulation, Volume 150, Issue Suppl_1 , Page A4141933-A4141933, November 12, 2024. However, due to a presumed good disease outcome, fatality rates of SVT in adults (above 25 years) are yet to be explored.Aim:This study aims to shed light on the mortality trends of SVT in the adult population across the United States from 1999 to 2020.Methodology:The
This study aimed to identify proteomic expression patterns in large core infarct patients undergoing MT to inform potential pharmacological intervention targets.Methods:The Blood And Clot Thrombectomy Registry And Collaboration (BACTRAC) tissue registry was reviewed for anterior circulation MT patients treated between June 2017-December 2023.
The overall goal of this study is to determine if MRI lesion patterns are predictive of AF detection by ICM.Methodology:Cases of consecutive patients (1/1/2015 - 12/31/2017) with MRI-confirmed stroke performed 48h from time last known well and prior to endovascular treatment were retrospectively analyzed.
So they took the patient urgently to cath: 100% occlusion of inferior obtuse marginal branch of the circumflex, with collateral circulation. Had the cardiologists followed NSTEMI or transient STEMI guidelines, which recommend non-urgent cath, the patient could have redeveloped an OMI and had a worse outcome.
Exercise and Coronary Atherosclerosis | Circulation There are a few pieces of evidence, however, that can give endurance athletes some reassurance that they’re not headed to an early grave. This is concerning because higher CACS are associated with a greater risk for adverse cardiovascular outcomes.
However, none of the formulas have proven to be definitively better than another and none are well correlated with outcomes or events! None is considered definitive due to the paucity of data (and conflicting data) relating QTc to outcomes. Heart 2002;87:220228 This 2017 article by Vandenberk B et al. This study by Patel et al.
Adult Cardiac Surgery Database Lead Author Title Publication Date Jacob Raphael Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis The Annals of Thoracic Surgery January 2024 Joseph Sabik Multi-Arterial versus Single-Arterial Coronary Surgery: Ten Year Follow-up of One Million (..)
Program Designations Access and Publications (A&P) 1 Participant User File (PUF) 2 Task Force on Funded Research (TFR) 3 Special Projects 4 Adult Cardiac Surgery Database Lead Author Title Publication Date William Keeling 2 National Trends in Emergency Coronary Artery Bypass Grafting European Journal of Cardiothoracic Surgery October 2023 Jake (..)
Circulation, Volume 150, Issue Suppl_1 , Page A4141539-A4141539, November 12, 2024. Introduction:Atrial fibrillation (AF) is a common cardiac arrhythmia, the risk of cardiovascular adverse outcome rises when it coexists with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI).
Circulation, Ahead of Print. Therefore, we developed and validated the AHA Predicting Risk of CVD EVENTs (PREVENT) equations among US adults aged 30-79 years without known CVD.Methods:The derivation sample included individual-level participant data from 25 datasets (N=3,281,919) between 1992-2017.
Cardiac Syncope ("True Syncope") Independent Predictors of Adverse Outcomes condensed from multiple studies 1. These premonitory symptoms were negative predictors of adverse outcomes in EGSYS. Abnormal ECG – looks for cardiac syncope. Hemoglobin less than 10 (SF rule) 6. Syncope with Exertion (EGSYS) 7. S yncope while supine (EGSYS) 8.
Back to the case: Repeat ECG after return of spontaneous circulation is shown. A 2017 trial named CULPRIT SHOCK found that in patients with cardiogenic shock, a strategy of culprit vessel PCI only was associated with better outcomes than immediate multivessel PCI. in absolute terms!
Angiography usually reveals an absence of collateral circulation to the infarct zone. Circulation , 88 (3), 896904. The above said given the patient's age, co-morbidities, and the decision that he was not a surgical candidate, there was little to do clinically that would alter this patient's guarded outcome.
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