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Circulation, Ahead of Print. This update summarizes relevant clinical data published since the 2017 American Heart Association scientific statement on KD related to diagnosis, cardiac imaging in acute KD treatment, and long-term management.
Therefore, we clinically investigate whetherAPOE4contributes to cerebral hemodynamic and cognitive impairment in subjects with asymptomatic carotid artery stenosis or occlusion.Methods and ResultsA crosssectional observational study was conducted between January 2017 and March 2022.
Circulation: Genomic and Precision Medicine, Ahead of Print. BACKGROUND:Truncating variants (TTNtvs) in the titin (TTN) gene have been associated with cardiomyopathies or arrhythmias (C/A) and autosomal recessive neuromuscular diseases (NM). Burden testing was performed using controls in the genome aggregation database v3.1.2
Background:Computerized tomography perfusion (CTP) imaging serves as a valuable modality for the assessment of individuals with a large vessel anterior circulation stroke. Stroke, Volume 55, Issue Suppl_1 , Page ATP141-ATP141, February 1, 2024. RAPID software estimates the infarct core using CBF <30%.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. BACKGROUND:Differences in the quality of hospitals where Black and White patients receive coronary artery bypass grafting (CABG) surgery have been documented.
Circulation. For more information: [link] References: 1 Maurer M, Elliott P, Comenzo R, et al. Addressing common questions encountered in the diagnosis and management of cardiac amyloidosis. 135(14):1357-1377. 2 Siddiqi O., Cardiac Amyloidosis: An Update on Pathophysiology, Diagnosis, and Treatment. Trends Cardiovasc Med.
Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:A high permanent pacemaker implantation (PPI) risk remains a concern of self-expandable transcatheter aortic valve implantation, despite the continued improvements in implantation methodology.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. BACKGROUND:The ongoing TANGO2 (Telephone Assisted CPR. Inclusion criteria were witnessed event, bystander on the scene with previous CPR training, age above 18 years of age, and no signs of trauma, pregnancy, or intoxication.
Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:MRI-derived myocardial extracellular volume fraction (ECV) is elevated in the presence of fibrosis, amyloid deposition, inflammation and edema.
ConclusionsIn thrombectomy‐eligible patients with anterior circulation large‐vessel occlusion, IVT improves functional outcome independent of grade of reperfusion and distal thrombus migration. to –0.17];P=0.002) and remained beneficial in those with unsuccessful reperfusion (mTICI ≤2a; ß=–0.47 [95% CI, −0.96 to 0.01];P=0.05).ConclusionsIn
Collateral status is a well-documented marker of reperfusion and mortality in patients with large vessel occlusion (LVO) anterior circulation strokes, which account for approximately one-third of AIS. Methods:We retrospectively evaluated AIS patients treated at our institution between January 2017 and January 2023.
Circulation, Volume 150, Issue Suppl_1 , Page A4135852-A4135852, November 12, 2024. Background:Vertebrobasilar artery stenosis (VBAS) can cause posterior circulation strokes (PCS). Optimal management is controversial, with options including medical therapy (MT), endovascular stenting (ES), and surgical revascularization (SR).
However, it has not been clinically investigated in patients with asymptomatic CASO.Methods:A cross-sectional observational study was conducted between January 2017 and March 2022. We reportedAPOE4induces neurovascular dysfunction and cognitive impairment in a mouse model of CASO.
Circulation, Volume 150, Issue Suppl_1 , Page A4146022-A4146022, November 12, 2024. Background:Rarely, SARS-CoV-2 will lead to myocarditis associated with Multisystem Inflammatory Syndrome in Children (MIS-C). It remains unclear why MIS-C only targets specific children. of cases respectively.
Circulation, Volume 150, Issue Suppl_1 , Page A4143624-A4143624, November 12, 2024. Background:In diabetic ketoacidosis (DKA), cardiac complications such as QTc interval prolongation can pose a risk for ventricular tachycardia. Inclusion criteria encompassed patients under 21 years with two 12-lead ECGs taken during and after DKA resolution.
Circulation, Volume 150, Issue Suppl_1 , Page A4138704-A4138704, November 12, 2024. It was carried out across 264 institutions and clinics from October 2017 to July 2021. Background:Statins are widely used for controlling dyslipidemia. Total 16,992 participants were enrolled.
Our investigation focused on delineating the distinctive features of ICAS-related LVOS to explore its underlying pathology.Methods:This is a cross-sectional comparison from a prospective, single-center cohort study of acute ischemic stroke from January 2017 to January 2023.
This randomized crossover trial assessed whether an artificial intelligence (AI) solution enhances diagnostic accuracy for these challenging lesions compared to conventional interpretation.Methods:From February 2017 to November 2021, 4,071 suspected acute ischemic stroke patients underwent initial and follow-up DWI.
Circulation: Cardiovascular Interventions, Ahead of Print. The derivation data set consisted of cases performed from 2014 to 2017, and the validation data set consisted of cases performed from 2019 to 2020. kg at all Congenital Cardiac Catheterization Project on Outcomes participating centers.
Spatial relationship of sites for atrial fibrillation drivers and atrial tachycardia in patients with both arrhythmias July 2017 International Journal of Cardiology 248(3) AF begets AF. Pierre Jaïs Circulation 2000 ) When such flutters transform into fibrillation, how does the spillover of signals occur to the contralateral atrium?
Circulation, Ahead of Print. BACKGROUND:The ability to predict recovery of left ventricular ejection fraction (LVEF) in response to guideline-directed therapy among patients with nonischemic cardiomyopathy is desired. Detailed voltage maps of the left ventricular endocardium were generated using the CARTO electroanatomic mapping system.
Circulation, Volume 150, Issue Suppl_1 , Page A4141279-A4141279, November 12, 2024. Methods:STEMI patients who underwent coronary revascularization therapy and cardiac magnetic resonance (CMR) at about 4 days and 6 months between 2017 and 2023 were included.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Background:Type 2 myocardial infarction (T2MI) and type 1 myocardial infarction (T1MI) differ with respect to demographics, comorbidities, treatments, and clinical outcomes. T1MI and 53.5% T2MI; mean age, 79±10.3 years; 47% female).
Circulation: Cardiovascular Imaging, Volume 16, Issue 11 , Page e015606, November 1, 2023. BACKGROUND:Pericardial late gadolinium enhancement (LGE) is usually associated with active pericarditis, but it is not infrequently found in patients after cardiac surgery even a long time after the intervention.
Edited by Bracey, Meyers, Grauer, and Smith A 50-something-year-old female with a history of an unknown personality disorder and alcohol use disorder arrived via EMS following cardiac arrest with return of spontaneous circulation. 2017 Oct 1;177(10):1520-1522. Circulation. JAMA Intern Med. doi: 10.1001/jamainternmed.2017.3191.
Epub 2017 Oct 16. Harjola VP, Mebazaa A, Celutkiene J, Bettex D, ET AL Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology. Eur J Heart Fail. 2018 Jan;20(1):16-37.
Circulation, Volume 150, Issue Suppl_1 , Page A4141522-A4141522, November 12, 2024. Background:Maternal nutritional status and periconceptional environmental conditions have been previously linked to the methylation of the vtRNA 2-1 promoter. Quantitative pyrosequencing was performed on all patients.
Circulation, Volume 150, Issue Suppl_1 , Page A4136698-A4136698, November 12, 2024. The prevalence of PFO was 65.9 % (377 patients), and 331 patients (57.9% of the total, 87.8% of those with PFOs) were diagnosed with HRPFO using cTTE or cTEE.
Results:437 cases with intracranial vessel occlusions in the anterior circulation, treated with EVT between 2017 and 2022 (41% women, median age 81 [IQR 70-88] years), were analyzed (M1: 261 (59.7%); proximal M2: 111(25.4%); M2 distal: 65 (14.9%).
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Background:Undiagnosed hypertension and uncontrolled blood pressure (BP) are common and contribute to excess cardiovascular morbidity and mortality. years (SD, 13.1), 147 (45%) were women, and 253 (80%) were of non-Hispanic White race.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. We included consecutive general medical patients aged 18 years or older. Patients were excluded if they had a contraindication to prophylaxis, including anticoagulation for another condition, acute bleeding, or comfort-only care.
Circulation: Heart Failure, Volume 16, Issue 11 , Page e010618, November 1, 2023. BACKGROUND:Obesity and adiposity are associated with an increased risk of heart failure with preserved ejection fraction (HFpEF); yet, specific underlying mechanisms remain unclear.
Circulation, Volume 150, Issue Suppl_1 , Page A4123899-A4123899, November 12, 2024. Identified echocardiograms were reviewed to confirm IVMS aneurysms and exclude sinus of Valsalva aneurysms. Patients with concurrent structural heart anomalies were excluded.
This study addresses this gap in the literature by evaluating the effectiveness of those prognostic tools in stroke patients treated in a rural area of the Midwest.Methods:We conducted a retrospective study of stroke patients treated with thrombolytics at Southern Illinois Healthcare Stroke Network from July 2017 to June 2024.
Introduction:Animal research suggests that HDL cholesterol (HDL-C) ameliorates reperfusion injury, a phenomenon that worsens clinical outcome following recanalization therapy for ischemic stroke.Hypothesis:We hypothesized that higher HDL-C levels have a guarding effect against cerebral reperfusion injury in human stroke survivors treated with thrombectomy.Methods:We (..)
Circulation, Ahead of Print. The primary non-inferiority endpoint was all-cause mortality, stroke, and major bleeding at 2-years between the two strategies.Results: The study enrolled 349 patients, 177 TAVR+LAAO and 172 TAVR+medical therapy, between December-2017 and November-2020 at 34 US centers. and HAS-BLED score was 3.0.
Hypertension was defined according to the 2020 International Society of Hypertension Guidelines (adults) and 2017 American Academy of Pediatrics Guidelines (children). Posterior circulation involvement was a negative predictor for response of hypertensive status to revascularization (OR, 0.10 [95% CI, 0.01–0.79]).CONCLUSIONHypertension
In this study, we investigated whether the clot composition or clot characteristics differed by the clot size using microscopic analysis of ischemic clot.Methods:We obtained the clots from 238 ischemic stroke patients who received endovascular treatment between July 2017 and July 2023 at Severance Stroke Center.
Background:We studied the effect of intravenous thrombolysis (IVT) before thrombectomy for anterior circulation large vessel occlusion (acLVO) on functional outcome and scrutinized its dependence on grade of reperfusion and distal thrombus migration.Methods:We included consecutive acLVO patients from our prospective registry of thrombectomy-eligible (..)
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