Journal of the American Heart Association

FEBRUARY 29, 2024

BackgroundDelayed cerebral ischemia represents a significant contributor to death and disability following aneurysmal subarachnoid hemorrhage. The lack of standardized experimental setups and outcome assessments, particularly regarding secondary vasospastic/ischemic events, may be partly responsible for the translational failure.

Ischemia 40

Ischemia Hemorrhage Blood Pressure Aneurysm 40

Stroke Journal

FEBRUARY 1, 2024

Background:Cerebral vasospasm is a well-known complication after aneurysmal subarachnoid hemorrhage (aSAH) and occurs more commonly in younger patients. Worse outcome was defined as 3-month modified Rankin Scale 4-6. Vasospasm was defined based on transcranial Doppler (TCD) criteria. years [SD 13.3], 65% female and 70% white).

Atherosclerosis 40

Atherosclerosis Aneurysm Hemorrhage Outcomes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. Whether CAA is associated with isolated subdural hemorrhage (SDH), without an accompanying intracerebral hemorrhage, remains unclear. Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025.

Hemorrhage 40

Hemorrhage Cerebrovascular Disease Dementia Document 40

Stroke Journal

FEBRUARY 1, 2024

Background:Nationwide data demonstrating the impact of the COVID-19 pandemic on hemorrhagic stroke outcomes are lacking.Methods:We used the National Inpatient Sample (2016-2020) to identify adults (>=18 years) with primary intracerebral hemorrhage (ICH) or subarachnoid hemorrhage (SAH).

COVID-19 40

COVID-19 Hemorrhage Public Health Inpatient 40

Stroke Journal

MARCH 20, 2025

BACKGROUND:Shorter times to initiate antihypertensive and anticoagulation reversal treatments enhance their benefits in acute intracerebral hemorrhage (ICH). Stroke, Ahead of Print. Improving workflows to optimize time performance metrics is strongly advocated.

Hemorrhage 40

Hemorrhage Stroke Strokes Hospital 40

Stroke Journal

JANUARY 30, 2025

Background:FDA clearance of fully automated artificial intelligence (AI)-based software for quantifying intracerebral hemorrhage (ICH) volumes has the potential to meaningfully impact the acute management of hemorrhagic stroke. Quantifying ICH volume in OAC-related ICH presents challenges due to variability of morphology and density.

Hemorrhage 40

Hemorrhage Stroke Strokes Research 40

Stroke Journal

JANUARY 30, 2025

Objective:Socioeconomic disparities significantly affect the treatment and outcomes of cardiovascular and cerebrovascular diseases, including acute ischemic stroke. SES was assessed by matching patient ZIP codes to median household income data from the Census for the years 2016-2022.

Outcomes 40

Outcomes Stroke Strokes Hospital 40

Stroke Journal

JANUARY 30, 2025

In this study, we wanted to see the prevalence of ischemic or hemorrhagic stroke in patients with metastatic cancer to the brain, the demographic characteristics, and associated comorbidities.Methods:We conducted a retrospective analysis using the National Inpatient Sample Database from 2016 to 2020.

Cancer 40

Cancer Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Background and Aims:Previous studies indicated the usual dose heparin(5000 IU bolus followed by 500~1250 IU/h) during mechanical thrombectomy(MT) is associated with an increased risk of hemorrhagic conversion without beneficial effect. vs 21.3%, p=0.04).

Hemorrhage 40

Hemorrhage Thrombolysis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:While predictors of seizure in aneurysmal subarachnoid hemorrhage (aSAH) patients have been explored, predictors for seizure in patients with angiogram-negative non-perimesencephalic SAH (an-NPSAH) are less understood. Neither intracerebral hemorrhage nor aneurysm securement modality was associated with seizure.

Aneurysm 40

Aneurysm Hemorrhage Academic Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Background:We identified that major ABO incompatible platelet transfusions are associated with poor intracerebral hemorrhage (ICH) outcomes, yet the driver for this relationship is unknown and does not appear to be related to impaired hemostasis. Conversely, acute ICH patients are known to develop remote ischemic lesions on brain MRI.

Hemorrhage 40

Hemorrhage Ischemia Risk Factors Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Whereas secondary analyses from randomized trials have demonstrated no differences in thrombectomy outcomes in transferred vs direct presentation strokes (1‐2), several registry based cohorts reported worse functional outcomes in those with transferred presentation mode (3‐4).

Hospital 40

Hospital Outcomes Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

We performed this analysis to identify the prevalence of atrial fibrillation and associated outcomes in symptomatic internal carotid artery stenosis patients undergoing CAS or CEA.Methods:We analyzed the data from the National inpatient sample (NIS) between January 2016 to December 2021. versus 18.8%

Atrial Fibrillation 40

Atrial Fibrillation Stents Stent Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Impact of race on outcomes in the treatment of intracranial aneurysm (IA) remains unclear. Data from 9 centers in the United States, Europe, and Asia for IA patients who undertook endovascular treatment (EVT) or microsurgical treatment (MST) between January 2016 and December 2020 were included for analysis. P< 001).

Aneurysm 40

Aneurysm Outcomes Stroke Strokes 40

Stroke Journal

MARCH 21, 2024

BACKGROUND:Patient-reported outcome measures (PROMs) describe health status from the perspective of the patient. Using the trial’s primary publication and protocol, we abstracted key study characteristics including all primary and secondary outcome measures. Only 1 trial used a PROM as a primary outcome.

Stroke 40

Stroke Strokes Outcomes Quality of Life 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

There is limited data on the influence of COVID‐19 on treatment and outcomes in patients with intracranial aneurysms. We aimed to investigate the impact of COVID‐19 on the overall complications, including ischemic stroke and subarachnoid hemorrhage (SAH) rates in patients treated for intracranial aneurysms (IAs).MethodsThis

COVID-19 40

COVID-19 Aneurysm Outcomes Inpatient 40

Stroke Journal

FEBRUARY 1, 2024

Background:Utilizing medical claims derived information, we evaluated temporal trends in post-acute care utilization pathways among patients with acute ischemic stroke (AIS) or intracerebral hemorrhage (ICH).Methods:Data Analytical sample included all Medicare enrollees with a primary discharge diagnosis (AIS or ICH) from 2016 to 2020.

Medicare 40

Medicare Hemorrhage Inpatient Nursing 40

Stroke Journal

FEBRUARY 1, 2024

Background:Cisternal score (CISCO), which is calculated based on quantification of blood clot in basal cisterns, has been shown to have good accuracy in predicting ventriculoperitoneal shunt requirement in patients with aneurysmal subarachnoid hemorrhage (aSAH). Data was collected prospectively as part of a quality improvement project.

Blood Clot 40

Blood Clot Aneurysm Hemorrhage Academic 40

Stroke Journal

JANUARY 30, 2025

As the eligibility criteria for MT ease, more patients will undergo the procedure who have risk factors for complications such as malignant edema or hemorrhagic conversion that require decompressive craniectomy (DC).

Stroke 40

Stroke Strokes Outcomes Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

The hospitals were grouped into quartiles based on the volume of MT procedures performed within the calendar year. The hospitals were grouped into quartiles based on the volume of MT procedures performed within the calendar year.

Hospital 40

Hospital Stroke Strokes Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionUnderstanding of patient benefit and improvement following mechanical thrombectomy in ischemic stroke has made tremendous strides in recent years, however clinicians still struggle to accurately predict patient outcomes and long‐term neurological functioning following large vessel occlusion and endovascular therapy.

Outcomes 40

Outcomes Stroke Strokes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Specific aspects of IRF care driving better vascular outcomes need further evaluation. Objectives:We evaluate the potential link between post-acute care, particularly care provided at inpatient rehabilitation facilities (IRF) (vs. Conclusions:Post-acute care at an IRF (vs.

Inpatient 40

Inpatient Hemorrhage Myocardial Infarction Nursing 40

Stroke Journal

JANUARY 30, 2025

Introduction:There is no established acute intervention for central retinal artery occlusion (CRAO) which often results in poor visual outcomes. There was no difference in sICH, vitreous hemorrhage, or neovascularization.Conclusions:This is the first case series comparing CRAO treated with TNK, tPA, and MM.

Hemorrhage 40

Hemorrhage Document Diabetes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Pregnancy and the postpartum period are associated with an increased risk of ischemic and hemorrhagic strokes. Stroke, Volume 55, Issue Suppl_1 , Page ATP273-ATP273, February 1, 2024.

Stroke 40

Stroke Strokes Hemorrhage Hospital 40

Dr. Smith's ECG Blog

FEBRUARY 6, 2024

Massive Transfusion for Motorcycle Collision with Hemorrhage, Troponin Elevated. Atrial fibrillation is also a predictor of worse outcomes in this case (Alborzi). 2016, April 13). : A Child with Blunt Trauma -- See how the ECG can be definite for myocardial contusion, but subtle, and what happens if you miss it. Zangouri, V.,

Tachycardia 115

Tachycardia Dysrhythmia Atrial Fibrillation Bradycardia 115

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Many studies have aimed to determine if heart failure (HF) is an independent risk factor in the development of AIS, but there is a paucity of literature describing the interventions and functional outcomes in this group of patients. AIS patients with CM and HF were compared to those without. 5.6%, p < 0.001) and EVT and tPA (0.9%

Heart Failure 40

Heart Failure Cardiomyopathy Inpatient Stroke 40

Stroke Journal

JANUARY 30, 2025

to identify patients with a diagnosis of AVM from the statewide inpatient and emergency department databases of Florida, Georgia, Maryland, New York, and Washington (2016-2019). Patients with a history of primary intracerebral hemorrhage or subarachnoid hemorrhage at baseline were classified as ruptured AVM (rAVM) patients.

Hemorrhage 40

Hemorrhage Medicare Inpatient Research 40

Stroke Journal

JANUARY 12, 2024

Further study of outcomes among diverse populations of stroke surrogate decision-makers may help to identify sources of strength and resiliency that may be broadly applicable. Surrogates self-identified as being involved in decisions about do-not-resuscitate orders, brain surgery, ventilator, feeding tube, or hospice/comfort care.

Stroke 40

Stroke Strokes Hemorrhage Outcomes 40

Journal of the American Heart Association

JANUARY 16, 2025

BackgroundTransport by mobile stroke units (MSUs), which provide access to computed tomography scanning and intravenous blood pressure medications and thrombolytics, reduces time to treatment and may improve shortterm functional outcomes for patients with acute stroke. had an intracerebral hemorrhage, and 31.1% versus 15.1%,P=0.86).

Stroke 40

Stroke Strokes Medicare Blood Pressure 40

Stroke Journal

JANUARY 30, 2025

Introduction:White matter hyperintensity (WMH) burden is associated with poor cognitive and functional outcomes after intracerebral hemorrhage (ICH). Stroke, Volume 56, Issue Suppl_1 , Page AWP199-AWP199, February 1, 2025. Deep-learning models provide a potential alternative to quantify WMH burden.

Hemorrhage 40

Hemorrhage Hospital Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:There has been limited study of outcomes among surrogate decision makers who make decisions on life-sustaining treatments after severe stroke. Patient characteristics were mean age: 74.6, Female: 51.8%, Mean NIHSS: 14.7, deceased at 3 months: 53.1%. Surrogate characteristics were mean age: 55.8,

Stroke 40

Stroke Strokes Hemorrhage Outcomes 40

Stroke Journal

JANUARY 30, 2025

Our primary outcome was post-discharge LTFU, defined as having zero post-discharge encounters within 12 months. Our secondary outcomes included having one or more outpatient visits with a provider, unplanned hospitalizations, and emergency department (ED) visits within 30 days post-discharge. vs. 47.4%); have an intracerebral (12.1%

Academic 40

Academic Stroke Strokes Risk Factors 40

Stroke Journal

JANUARY 30, 2025

Background:Non-contrast computed tomography (NCCT) markers have been commonly used to characterize hematomas in intracerebral hemorrhage (ICH). Univariate and multivariate analyses were performed between CT markers and variables of operative outcome with R v 4.3.1.Results:221 Results:221 patients met the inclusion criteria.

Hemorrhage 40

Hemorrhage Outcomes Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

The study outcome was a new speech pathology (SLT), occupational therapy (OT), or physical therapy (PT) encounter during the first year after discharge.Results:57,647 total cases were identified with 30% Medicare FFS, 33% Truven (Commercial) Medicare Advantage plan (65 years and older), and 37% Truven commercial (less than 65 years old).

Medicare 40

Medicare Stroke Strokes Outpatient 40

Stroke Journal

FEBRUARY 1, 2024

Chi-square or Fisher’s exact test were used for categorical variables; Wilcoxon’s rank sum test was used for the outcomes of SRT to bolus and SRT to puncture.Result:We identified 196 IHS who received emergent treatment: 58 (30%) in Pre and 138 (70%) in Post Intervention (p=0.05). There was no difference in baseline demographics.

Hospital 40

Hospital Nursing Hemorrhage Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Our primary study outcome was any stroke or major thrombotic event identified within 60 days of OHSS diagnosis in HCUP or during the index admission for OHSS in NIS. The low rate of outcome events after OHSS seen in each of our population-level analyses increases the reliability of these study results. were included from each dataset.

Thrombosis 40

Thrombosis Inpatient Embolism Myocardial Infarction 40

Stroke Journal

FEBRUARY 1, 2024

Data was compared to a previous review period (01/2016-12/2018; comprised of 8 spokes) and the statewide IVT rates recorded in GWTG. Symptomatic hemorrhage (sICH) was 3.0%, overall 30-day mortality was 5.6%, and sICH mortality was 1.0%. 39% (410/1055) of eligible patients were treated with IVT (vs.

Thrombolysis 40

Thrombolysis Stroke Strokes Education 40