Dr. Sanjay Gupta

MARCH 6, 2022

Today’s video is on the subject of heart failure. Heart failure is a chronic clinical syndrome characterised by the inability of the heart to pump out enough blood to meet the body’s requirements. Anything that affects the heart in a bad way may in its severest form lead to heart failure.

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Heart Failure Quality of Life ACE Inhibitor Exercise 40

Cardiovascular Diabetology

AUGUST 6, 2024

Data on major cardiovascular events (MACE; mortality, myocardial infarction, stroke, heart failure) through December 2021 were obtained from national registries. The use of cardioprotective GLD increased rapidly in recent years (2016–2021; 7–47%) and was more common in younger patients (66 vs. 68 years) and men (72.9%

Coronary Artery Disease 98

Coronary Artery Disease Diabetes Myocardial Infarction Heart Failure 98

DAIC

JULY 29, 2024

Edwards anticipates FDA approval of the JenaValve Trilogy Heart Valve System in late 2025, which will represent the first approved therapy for patients suffering from AR. Building on an investment made in 2016, Edwards has exercised its option to acquire Endotronix , a leader in heart failure (HF) management solutions.

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Innovation Aortic valve Aortic CMS 98

Journal of the American Heart Association

FEBRUARY 23, 2024

BackgroundThe effects of pharmacological therapy on cardiogenic shock (CS) survivors have not been extensively studied.

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Cardiogenic Shock Heart Failure Pharmacology Hospital 40

European Journal of Heart Failure

DECEMBER 7, 2023

Abstract Background and Aims Patients who experience hospitalizations due to heart failure (HF) face a significant risk of readmission and mortality. Methods We studied all adults admitted for a first HF hospitalization from 2016 to 2020 in France's Grand Est region. Results Among 67 476 admitted patients (mean age 80.3 ± 11.3 years,

Heart Failure 40

Heart Failure Hospital Outpatient Article 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionCardiomyopathy (CM) is a diverse pathology defined by both structural and functional changes in the heart. The National Inpatient Sample (NIS) database from 2016‐2019 for patients with a principal diagnosis of AIS using the ICD‐10 code I63 was queried. AIS patients with CM and HF were compared to those without.

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Heart Failure Cardiomyopathy Inpatient Stroke 40

CardiacWire

AUGUST 21, 2024

Johnson & Johnson expanded deeper into heart failure and interventional cardiology, acquiring interatrial shunt-maker V-Wave for $600M upfront and up to $1.7B The two companies are already well-acquainted, as J&J led V-Wave’s 2016 Series B and was involved in subsequent rounds. with certain milestones.

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Heart Transplant Heart Failure Interventional Cardiology Transplant 64

Cardiology Update

DECEMBER 11, 2023

In a recent study published in Circulation: Heart Failure , researchers analyzed a large group of individuals with various cardiopulmonary diseases who had undergone right heart catheterization. year follow-up, those with right ventricular dysfunction faced an increased risk of mortality and heart failure hospitalization.

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Obesity Hospital Outcomes Heart Failure 52

Cardiology Update

MARCH 17, 2024

Data were prospectively gathered from individuals aged 1 to under 18 years participating in the European Society of Cardiology EURObservational Research Programme Cardiomyopathy and Myocarditis long-term registry spanning from June 2014 to December 2016. Familial disease was identified in 47.3% (n = 253) of patients. months (IQR: 11.3–15.3),

Cardiomyopathy 119

Cardiomyopathy Pediatrics Heart Failure Research 119

Frontiers in Cardiovascular Medicine

FEBRUARY 14, 2024

Methods Using the Korean National Health Insurance Service database, we included patients aged ≥75 years with new-onset AF from January 2009 to December 2016 ( n  = 41,315). Objective To evaluate the impact of combined ERC and HLS on the risk of stroke in elderly patients with new-onset AF.

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Atrial Fibrillation Stroke Strokes Heart Failure 72

European Journal of Heart Failure

NOVEMBER 3, 2023

Among 475 patients with cardiac sarcoidosis, 119 (25.1%) were isolated cardiac sarcoidosis (iCS) based on the 2016 Japanese Circulation Society criteria. iCS was diagnosed according to the 2016 Japanese Circulation Society (JCS) guidelines. Among 475 patients with CS (mean age, 62.0 ± 10.9 years; During a median follow-up of 42.3

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Atrial Fibrillation Heart Failure Tachycardia Arrhythmia 40

Dr. S. Venkatesan MD

AUGUST 3, 2024

Gorter TM, van Veldhuisen DJ, Bauersachs et al Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2018 Jan;20(1):16-37.

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Circulation: Heart Failure

OCTOBER 27, 2023

Circulation: Heart Failure, Volume 16, Issue 11 , Page e010524, November 1, 2023. The role of obesity in RV dysfunction and adverse outcomes is unclear.METHODS:We examined patients undergoing right heart catheterization between 2005 and 2016 in a hospital-based cohort. P<0.001). Over median of 7.3

Obesity 40

Obesity Outcomes Heart Failure Pulmonary 40

Heart BMJ

MAY 10, 2024

years; 67% men, 33% women) with severely symptomatic HOCM who underwent PIMSRA from October 2016 to September 2017 were included. Malignant ventricular arrhythmia and heart failure events were not observed. Methods 27 patients (age: 44.3±15.5 Trial registration number NCT02888132.

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Ablation Exercise Heart Failure Cardiomyopathy 52

DAIC

MAY 16, 2024

Apparent treatment-resistant hypertension is defined as the need to take three or more types of anti-high blood pressure medication daily and is associated with an increased risk for stroke , coronary heart disease , heart failure , and all-cause mortality. Over a period of 9.5 of white adults.

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Hypertension Blood Pressure Health Disparities Heart Attack 105

Heart BMJ

JUNE 25, 2024

The primary outcome was the first occurrence of major cardiovascular events defined as a composite of hospitalisation for acute coronary syndrome (non-fatal myocardial infarction and unstable angina), fatal myocardial infarction, non-fatal and fatal stroke, sudden death and heart failure.

Cardiovascular Disease 59

Cardiovascular Disease Myocardial Infarction Pharmacology Angina 59

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

from 2016‐2019 and secondary diagnosis of T2DM. Data was weighted to allow for representative nationwide estimates.ResultsWe identified 426,549 patients who were admitted with a primary diagnosis of TIA between 2016 and 2019. The primary diagnosis of the readmission was used to identify the etiology of readmission.

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Diabetes Coronary Artery Disease Atrial Fibrillation Dementia 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

x) from 2016‐2019. The rate of 30‐day readmission was overall stable (7.34% in 2016 and 7.70% in 2019; p=0.42), but the 90‐day readmission rate slightly increased from 11.69% in 2016 to 12.47% in 2019 (p=0.04). ConclusionThe annual rate of 90‐day readmission, but not 30‐day readmission, increased from 2016 to 2019.

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Hemorrhage Coronary Artery Disease Obesity Heart Failure 40

Dr. Smith's ECG Blog

MARCH 6, 2020

NT-proBNP values less than 300 pg/ml have a 99% negative predictive value for excluding congestive heart failure. A cutoff of 1200 pg/ml for patients with a normal eGFR is very specific for heart failure. Troponin I was 0.054 ng/mL NT-ProBNP was 8316 (0-900 pg/mL). "

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Heart Failure Tachycardia Atrial Flutter Cardiomyopathy 52

Stroke Journal

FEBRUARY 1, 2024

We then identified patients receiving GLP1RA or SGLT2i and evaluated trends over time.Results:4131 patients were identified of which 2045 (49.4%) had a diagnosis of diabetes. Of these patients 60/2045 (2.9%) were on GLP1RA while 35/2045 (1.7%) were on SGTLi for total of 4.6%.

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Diabetes Stroke Strokes Kidney Disease 40

Stroke Journal

FEBRUARY 1, 2024

Annual follow-up interviews were conducted from inception until 2016 to determine outcomes of interest. Hospital records were reviewed and incident MACE, defined as the composite of incident stroke, myocardial infarction, or heart failure, was adjudicated using standard criteria. for all; IRR 0.44, 95% CI 0.23 in females).Conclusion:Among

Myocardial Infarction 40

Myocardial Infarction Blood Pressure Outcomes Diet 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

x) from 2016‐2019 using the Nationwide Readmission Database (NRD). Data was weighted to allow for representative nationwide estimates.ResultsA total of 260,854 patients were admitted with a primary diagnosis of ICH between 2016‐2019. The mean age of the cohort was 68.49 years, with 52.6% being male.

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Hemorrhage Risk Factors Coronary Artery Disease Obesity 40

Dr. S. Venkatesan MD

FEBRUARY 20, 2024

SCD is the leading cause of mortality in heart failure. N Engl J Med 2016; 375:1221-1230) Why ICD doesn’t work well in NDCM ? Bardy GH, Lee KL, Mark DB, Poole JE, Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. 2016 Sep 29;375(13):1221-30. N Engl J Med. 2005 Jan 20;352(3):225-37.

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Heart Failure Defibrillator Sudden Cardiac Death Cardiomyopathy 52

Journal of Cardiovascular Electrophysiology

FEBRUARY 13, 2024

Methods Consecutive patients with bradycardia indicated for pacing from 2016 to 2022 were prospectively followed for the clinical endpoints of heart failure (HF)-hospitalizations and all-cause mortality at 2 years.

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Bradycardia Physiology Pacemaker Heart Failure 40

Cardiometabolic Health Congress

JULY 25, 2023

There are significant data that show that if you have obesity, you have a high risk of developing coronary heart disease, heart failure, type 2 diabetes (T2D) or risk factors such as hypertension and dyslipidemia. [1] Is the obesity paradox a real phenomenon?

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Obesity BMI Heart Failure Cardiovascular Disease 52

DAIC

JANUARY 22, 2024

(AskBio), a gene therapy company wholly owned and independently operated as a subsidiary of Bayer AG , announced that it is initiating GenePHIT (Gene PHosphatase Inhibition Therapy), a Phase 2 trial of AB-1002 (also known as NAN-101 ) for the treatment of congestive heart failure (CHF). Heart failure. 2016:25:2. [5]

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Heart Failure Public Health Cardiomyopathy 105

Stroke Journal

FEBRUARY 1, 2024

Additionally, those with a history of kidney failure (2, 1.76 - 2.27), liver disease (1.32, 1.11 - 1.56), and heart failure (1.59, 1.35 - 1.86) had higher odds of experiencing MAVE. Patients were followed up for up to 24 weeks postpartum.

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Inpatient Hypertension Document Obesity 40

EMS 12-Lead

JUNE 1, 2022

LBBB and Heart Failure ECG findings of uncomplicated LBBB (that is, no criteria met for m-Sgarbossa criteria) are so ubiquitous in clinical medicine that it’s easy to overlook the nefarious sequelae of this pathology when no circumstance of OMI are present. European Heart Journal, 28 , 2449-2455. [7] 3] Meyers, H. 4] Dodd, K.

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Heart Failure Myocardial Infarction Bradycardia Cardiomyopathy 52

Dr. Smith's ECG Blog

DECEMBER 5, 2023

References Law YM, Lal AK, Chen S, Čiháková D, Cooper LT Jr, Deshpande S, Godown J, Grosse-Wortmann L, Robinson JD, Towbin JA; American Heart Association Pediatric Heart Failure and Transplantation Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young and Stroke Council.

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Pediatrics Pericarditis COVID-19 Congenital Heart Disease 115

Ken Grauer, MD

AUGUST 16, 2024

PEARL # 2: In the absence of associated heart failure ( cardiogenic shock ) — sinus tachycardia is not a common finding in acute MI. For now — Let's continue with ECG signs consistent with and suggestive of acute RV "Strain". Sinus Tachycardia and RAD — as already noted above.

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Blog Tachycardia Cardiogenic Shock Pulmonary 131

BoardVitals - Cardiovascular

JANUARY 18, 2021

Other trials that evaluated this subject were the WOEST trial (2013), Pioneer AF-PCI trial (2016), and ISAR-TRIPLE (2015). Explanation: The RE-DUAL PCI trial evaluated differences between triple therapy and dual therapy using antiplatelets/anticoagulant. These are the main aspects of the findings related to this trial.

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Bicuspid/Mitral Atrial Fibrillation Chest Pain Obesity 52

Dr. Paddy Barrett

AUGUST 15, 2023

Prevalence of Optimal Metabolic Health in American Adults: National Health and Nutrition Examination Survey 2009-2016. But this force multiplication of risk exists for many other major medical conditions that are likely to be the cause of early death also. PMID: 19138424; PMCID: PMC2635363. 4 Araújo J, Cai J, Stevens J. doi: 10.1089/met.2018.0105.

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Blood Pressure Risk Factors Diabetes Cholesterol 52

Circulation

JANUARY 23, 2024

BACKGROUND:Guideline-directed medical therapies (GDMTs) are the mainstay of treatment for heart failure with reduced ejection fraction (HFrEF), but they are underused.

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Heart Failure Medicare Circulation Outcomes 45

DAIC

JULY 24, 2024

About AFib, AI and Clinical Trials from HRS 2024 The American Heart Association defines AFib as a quivering or irregular heartbeat (arrhythmia) that can lead to blood clots, stroke, heart failure, and other heart-related complications. 1 Approximately 33 million patients worldwide are living with AFib.

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Atrial Fibrillation AFIB Ablation Technology 105

DAIC

JUNE 19, 2024

In July 2023 Eko Health announced a partnership with Japanese Life Sciences company Astellas Pharma to develop a non-invasive device Digital Therapeutics (DTx) solution for heart failure patients. In April 2022 BMS had received FDA approval for Camzyos, the first drug developed specifically for targeting HCM.

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Society of Thoracic Surgeons - Research

APRIL 20, 2023

Published Research kschukar Thu, 04/20/2023 - 11:12 Recently published (2016 – present) manuscripts utilizing STS data: Adult Cardiac Surgery, General Thoracic Surgery, Congenital Heart Surgery, and Intermacs/Pedimacs.

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Research Coronary Artery Bypass Graft Aortic valve Congenital 52

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Published Research kschukar Thu, 04/20/2023 - 11:12 Recently published (2016 – present) manuscripts utilizing STS data: Adult Cardiac Surgery, General Thoracic Surgery, Congenital Heart Surgery, and Intermacs/Pedimacs.

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Research Coronary Artery Bypass Graft Aortic valve Congenital 52