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Background:Mechanical thrombectomy (MT) as treatment for acute ischemic stroke (AIS) has demonstrated superior functional outcomes compared to intravenous thrombolysis (IVT). Stroke, Volume 56, Issue Suppl_1 , Page ATP115-ATP115, February 1, 2025. Matched propensity scores were used to adjust for baseline differences across 36 factors.
Subjects were divided into "intravenous thrombolysis group" and "non-intravenous thrombolysis group". Result:A total of 1971 patients (437 thrombolysis) were included. In the external validation set, the AUC-ROC values of "PAIST Scale" were 0.855 in the non-thrombolysis group and 0.778 in the thrombolysis group.
Secular changes were assessed per 5‐year cohorts (2000–2005, 2006–2010, 2011–2015, 2016–2020). In patients with NIHSS score ≥10, intravenous thrombolysis frequency increased from 1.6% In patients with NIHSS score 6–9, intravenous thrombolysis frequency increased from 0.5% to 2.8%.
In an exploratory analysis, we compared outcomes on the basis of successful recanalization (modified Thrombolysis in Cerebral Infarction 2b3).RESULTSAmong Excellent outcome (modified Rankin Scale 01) and symptomatic intracranial hemorrhage were secondary outcomes.
Introduction:The extended Thrombolysis in Cerebral Infarction (eTICI) scale has been demonstrated to correlate strongly with clinical outcomes. Stroke, Volume 55, Issue Suppl_1 , Page ATP211-ATP211, February 1, 2024.
Pre-transfer variables independently associated with clinical improvement were intravenous thrombolysis use, more distal occlusions, and lower serum glucose; variables associated with deterioration included more proximal occlusions and higher serum glucose.
Intravenous thrombolysis was administered in 39.6%. The primary outcome was the first‐pass effect (FPE), defined as expanded Treatment in Cerebral Infarction (TICI) 2c/3 on the first pass. male, median age 75 (interquartile range 65–82) years, and median National Institutes of Health Stroke Scale score 8 (5–12).
Method:We searched Pubmed, Cochrane, and Embase from 2015 to August 2024, which compared EVT in OAC and Non-OAC patients with acute ischemic stroke. In such a population, the safety and efficacy of EVT remain uncertain, with emphasis on the risk of intracranial hemorrhage (ICH).Method:We Safety outcomes included ICH and 90 days mortality.
Intravenous thrombolysis was administered in 39.6%. Previous studies in LVO and MeVO have demonstrated a correlation between good clinical outcomes and the first pass effect (FPE, eTICI 2c/3 on the first pass) but no differences in FPE rates or clinical outcomes between first‐line endovascular therapy techniques.1‐6
The commonest causes of MINOCA include: atherosclerotic causes such as plaque rupture or erosion with spontaneous thrombolysis, and non-atherosclerotic causes such as coronary vasospasm (sometimes called variant angina or Prinzmetal's angina), coronary embolism or thrombosis, possibly microvascular dysfunction.
2015 Nov;20(6):570-7. Matetzky S, Freimark D, Chouraqui P, et al. Emergency Medicine Journal 34(2):119. July 2016. Goldwasser D, Senthlikumar A, Bayes de Luna A. Lateral MI Explains the Presence of Prominent R Wave (R ≥ S) in V1. Ann Noninvasive Electrocardiol. Anand U, Kulkarni MD, Renee B.
Background:Non-Hispanic Black (NHB) and other minority patients in the United States (US) receive intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) less frequently compared with non-Hispanic White (NHW) patients during acute ischemic stroke (AIS) admission. Stroke, Volume 56, Issue Suppl_1 , Page AWP257-AWP257, February 1, 2025.
Background:The benefits of endovascular thrombectomy (EVT) for posterior cerebral artery (PCA) occlusion remain controversial, but intravenous thrombolysis (IVT) has proven benefit across nearly all ischemic stroke types.
Background:Prior studies have shown that individuals who have an in-hospital stroke are less likely to receive thrombolysis. We used national death index data to determine death at 30 days post-discharge.Results:Among 13134 strokes from 1993-2015, 1152 (9%) occurred in the hospital. in1993/94 (p=0.003).
Here is an old (2015), but still very relevant, lecture on T-wave inversion by Dr. Smith: 40 minute lecture on T-wave inversion Learning points : T-waves are often dynamic in ACS and may hint at reperfusion and re-occlusion before the ST-segment does.
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