2015, Outcomes and Thrombolysis - Cardiovascular Update

Abstract TP115: Differences in the Medical Management of Post-Stroke Sequelae Among Patients Treated with Mechanical Thrombectomy vs Intravenous Thrombolysis

Stroke Journal

JANUARY 30, 2025

Background:Mechanical thrombectomy (MT) as treatment for acute ischemic stroke (AIS) has demonstrated superior functional outcomes compared to intravenous thrombolysis (IVT). Yet AIS survivors often experience a range of unstudied post-stroke complications which negatively affect patient reported outcomes.

Thrombolysis

Thrombolysis Stroke Strokes Quality of Life

Nationwide Trends in Reperfusion Therapy and Outcomes of Acute Ischemic Stroke According to Severity: The Japan Stroke Data Bank

Stroke: Vascular and Interventional Neurology

SEPTEMBER 12, 2023

We investigated long‐term trends of reperfusion therapy and outcomes according to the stroke severity.MethodsPatients with acute ischemic stroke registered in the prospective nationwide hospital‐based registry between 2000 and 2020 were examined. Secular changes were assessed per 5‐year cohorts (2000–2005, 2006–2010, 2011–2015, 2016–2020).

Stroke

Stroke Strokes Outcomes Thrombolysis

Influence of Comorbidity on Endovascular Thrombectomy Outcomes for Medium‐Vessel Occlusion Stroke: A Nationwide Prospective Observational Study

Stroke: Vascular and Interventional Neurology

JANUARY 3, 2025

BACKGROUNDComorbidity burden may affect the outcome following endovascular thrombectomy (EVT) for mediumvessel occlusions. The primary outcome was a favorable outcome (modified Rankin Scale 02) at 90 days after EVT in relation to comorbidity burden. Stroke: Vascular and Interventional Neurology, Ahead of Print.

Outcomes

Outcomes Stroke Strokes Hemorrhage

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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Abstract TMP91: Clinical Change During Inter-Hospital Transfer for Thrombectomy: Incidence, Associated Factors and Relationship With Outcome

Stroke Journal

FEBRUARY 1, 2024

Pre-transfer variables independently associated with clinical improvement were intravenous thrombolysis use, more distal occlusions, and lower serum glucose; variables associated with deterioration included more proximal occlusions and higher serum glucose.

Hospital

Hospital Outcomes Thrombolysis Document

Abstract WP248: Endovascular Thrombectomy for Acute Ischemic Stroke in Anticoagulated Patients

Stroke Journal

JANUARY 30, 2025

Introduction:Endovascular thrombectomy (EVT) is effective in treating acute ischemic stroke, with research showing improved functional outcomes compared to medical treatment alone. Method:We searched Pubmed, Cochrane, and Embase from 2015 to August 2024, which compared EVT in OAC and Non-OAC patients with acute ischemic stroke.

Stroke

Stroke Strokes Thrombolysis Outcomes

First?Line Stent Retriever Versus Contact Aspiration or Combined Technique for Endovascular Therapy of Posterior Cerebral Artery Occlusion Stroke: The PLATO Study

Stroke: Vascular and Interventional Neurology

NOVEMBER 17, 2023

The primary outcome was the first‐pass effect (FPE), defined as expanded Treatment in Cerebral Infarction (TICI) 2c/3 on the first pass. Intravenous thrombolysis was administered in 39.6%. FPE was associated with higher rates of favorable outcomes (modified Rankin scale score 0–2: 58% versus 43.4%;P=0.01; 0.95];P=0.04).

Stents

Stents Stent Stroke Strokes

Abstract TP211: TICI Scoring Reliability in Proximal vs Distal Vessel Thrombectomy: A Comparative Analysis

Stroke Journal

FEBRUARY 1, 2024

Introduction:The extended Thrombolysis in Cerebral Infarction (eTICI) scale has been demonstrated to correlate strongly with clinical outcomes. Stroke, Volume 55, Issue Suppl_1 , Page ATP211-ATP211, February 1, 2024.

Thrombolysis

Thrombolysis Stroke Strokes Outcomes

Abstract 012: First?line Stent Retriever Versus Contact Aspiration or Combined Technique for Posterior Cerebral Artery Occlusion EVT

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Previous studies in LVO and MeVO have demonstrated a correlation between good clinical outcomes and the first pass effect (FPE, eTICI 2c/3 on the first pass) but no differences in FPE rates or clinical outcomes between first‐line endovascular therapy techniques.1‐6 Intravenous thrombolysis was administered in 39.6%. of patients.

Stents

Stents Stent Outcomes Thrombolysis

Right precordial ST depression in a patient with chest pain

Dr. Smith's ECG Blog

AUGUST 3, 2017

These patients had worse outcomes than patients with ST depression without occlusion; half of these were circumflex. 2015 Nov;20(6):570-7. There are several studies that indirectly reveal the proportion of STEMIs that are isolated to the posterior wall, and they range from 3% to 11%. (1, J Am Coll Card 1999;34(3):748-53. July 2016.

Chest Pain

Chest Pain Myocardial Infarction STEMI Ischemia

Abstract WP199: Outcomes Following Posterior Cerebral Artery Thrombolysis vs Medical Management in those with Atrial Fibrillation

Stroke Journal

FEBRUARY 1, 2024

Background:The benefits of endovascular thrombectomy (EVT) for posterior cerebral artery (PCA) occlusion remain controversial, but intravenous thrombolysis (IVT) has proven benefit across nearly all ischemic stroke types. to 2.87) with no difference in length of hospital stay (adjusted β 0.26, 95% -0.71

Atrial Fibrillation

Atrial Fibrillation Thrombolysis Outcomes Embolism

Abstract WP257: Persistent Racial Disparity Despite Higher Income in Odds of Receiving Mechanical Thrombectomy and Thrombolysis for Acute Ischemic Stroke Admissions 2006-2021

Stroke Journal

JANUARY 30, 2025

Background:Non-Hispanic Black (NHB) and other minority patients in the United States (US) receive intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) less frequently compared with non-Hispanic White (NHW) patients during acute ischemic stroke (AIS) admission. Stroke, Volume 56, Issue Suppl_1 , Page AWP257-AWP257, February 1, 2025.

Thrombolysis

Thrombolysis Stroke Strokes Hospital

Abstract WMP42: Trends of In-Hospital Strokes Over Time: Results From the Greater Cincinnati and Northern Kentucky Stroke Study

Stroke Journal

FEBRUARY 1, 2024

Background:Prior studies have shown that individuals who have an in-hospital stroke are less likely to receive thrombolysis. We used national death index data to determine death at 30 days post-discharge.Results:Among 13134 strokes from 1993-2015, 1152 (9%) occurred in the hospital. in1993/94 (p=0.003).

Hospital

Hospital Stroke Strokes Thrombolysis

What happens when you give morphine for chest pain in ACS? And what is pseudo-normalization of T-waves?

Dr. Smith's ECG Blog

MARCH 14, 2025

Here is an old (2015), but still very relevant, lecture on T-wave inversion by Dr. Smith: 40 minute lecture on T-wave inversion Learning points : T-waves are often dynamic in ACS and may hint at reperfusion and re-occlusion before the ST-segment does. See this case: A man his 50s with chest pain. Am Heart J. 2005;149:10431049.

Chest Pain

Chest Pain STEMI Myocardial Infarction Ischemia

Abstract TP115: Differences in the Medical Management of Post-Stroke Sequelae Among Patients Treated with Mechanical Thrombectomy vs Intravenous Thrombolysis

Nationwide Trends in Reperfusion Therapy and Outcomes of Acute Ischemic Stroke According to Severity: The Japan Stroke Data Bank

Influence of Comorbidity on Endovascular Thrombectomy Outcomes for Medium‐Vessel Occlusion Stroke: A Nationwide Prospective Observational Study

Webinars

Abstract TMP91: Clinical Change During Inter-Hospital Transfer for Thrombectomy: Incidence, Associated Factors and Relationship With Outcome

Abstract WP248: Endovascular Thrombectomy for Acute Ischemic Stroke in Anticoagulated Patients

First?Line Stent Retriever Versus Contact Aspiration or Combined Technique for Endovascular Therapy of Posterior Cerebral Artery Occlusion Stroke: The PLATO Study

Abstract TP211: TICI Scoring Reliability in Proximal vs Distal Vessel Thrombectomy: A Comparative Analysis

Abstract 012: First?line Stent Retriever Versus Contact Aspiration or Combined Technique for Posterior Cerebral Artery Occlusion EVT

Right precordial ST depression in a patient with chest pain

Abstract WP199: Outcomes Following Posterior Cerebral Artery Thrombolysis vs Medical Management in those with Atrial Fibrillation

Abstract WP257: Persistent Racial Disparity Despite Higher Income in Odds of Receiving Mechanical Thrombectomy and Thrombolysis for Acute Ischemic Stroke Admissions 2006-2021

Abstract WMP42: Trends of In-Hospital Strokes Over Time: Results From the Greater Cincinnati and Northern Kentucky Stroke Study

What happens when you give morphine for chest pain in ACS? And what is pseudo-normalization of T-waves?

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