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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

35 In a large multicenter double-blind randomized trial (LoDoCo2) involving 5,522 patients with clinically stable coronary artery disease, almost all of them on statin therapy, colchicine, 0.5 colchicine which poses the greatest risk among patients 65 or older who may have declining liver or kidney function.38 2013;368(21):2004-2013.

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Chest pain followed by 6 days of increasing dyspnea -- what happened?

Dr. Smith's ECG Blog

Denying patients the potential benefit of revascularization just because their symptoms have lasted a certain amount of time shows poor understanding of the pathophysiology of myocardial ischemia. There were no other causes of dyspnea apparent and thus we can assume that myocardial ischemia started 6 days prior. link] [2] Oliva, P.