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Abstract WMP13: The Modifying Effects of Psychosocial Health on the Association Between Cerebrovascular Health and Dementia Risk: The Atherosclerosis Risk in Communities (ARIC) Neurocognitive Study

Stroke Journal

Introduction:Associations between magnetic resonance imaging (MRI) markers of vascular pathology and dementia risk in older adults have been established, but it remains less clear how lifestyle factors may modify this association. Incident dementia cases were identified from time of imaging through December 31, 2019 (median follow-up: 6.4

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APOE4 & Cardiovascular Risk

Dr. Paddy Barrett

Being a carrier of the APOE4 gene variant is associated with higher rates of the most common type of dementia, late-onset dementia. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. What to do?

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Abstract WMP18: The Association between Cerebral Microbleed Patterns and Incident Dementia: The ARIC-Neurocognitive Study

Stroke Journal

Background:Cerebral microbleeds (CMBs) are associated with incident dementia, but the impact of specific CMB patterns is unclear. This study investigates the association between CMB patterns and dementia risk in the community-based longitudinal Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS).Methods:All