2010 and Cholesterol - Cardiovascular Update

Association of cumulative non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with the risk of cardiometabolic disease

Frontiers in Cardiovascular Medicine

NOVEMBER 19, 2024

BackgroundOne measurement of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is considered to be associated with insulin resistance and cardiovascular disease (CVD) risk. The participants were divided into quartiles bases on their cum NHHR.

Cholesterol

Cholesterol Cardiovascular Disease Cancer Diabetes

Cardiovascular Disease and Deaths On the Rise

CardiacWire

JANUARY 31, 2025

In 2010, the AHA released a 2020 goal to improve the CV health of all Americans by 20%, while reducing CVD and stroke deaths by 20%. However, theres light at the end of the cardiovascular tunnel thanks to advancements in drugs like GLP-1s and new cholesterol controls, which mean heart disease isnt a death sentence like it used to be.

Cardiovascular Disease

Cardiovascular Disease Obesity Heart Disease Public Health

Heterogeneity in the Prevalence of Cardiovascular Risk Factors by Ethnicity and Birthplace Among Asian Subgroups: Evidence From the 2010 to 2018 National Health Interview Survey

Journal of the American Heart Association

FEBRUARY 29, 2024

Generalized linear models with Poisson distribution were used to examine the prevalence and prevalence ratios of self‐reported hypertension, diabetes, high cholesterol, physical inactivity, smoking, and overweight/obesity among Asian subgroups compared with US‐born NHW adults.

Risk Factors

Risk Factors Obesity Diabetes Cholesterol

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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APOE4 & Cardiovascular Risk

Dr. Paddy Barrett

AUGUST 22, 2023

Every lipoprotein particle has one APO B protein. ( **Please note the B ) When we measure APO B levels, this is what we are measuring to give an estimate of the number of cholesterol particles and the subsequent risk of cardiovascular disease. APO E is also centrally involved in cholesterol metabolism. 2010 Aug 5;3:53-64.

Cholesterol

Cholesterol Dementia Coronary Artery Disease Cardiovascular Disease

Abstract 258: Comorbidities Associated with Exclusion from rtPA in Obese Ischemic Stroke Patients with History of Smoking

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Specifically, a history of diabetes and higher total cholesterol were associated with rtPA exclusion in obese AIS patients with a history of smoking. Univariate analysis was used to differentiate between risk factors and demographics associated with exclusion and inclusion from rtPA.

Obesity

Obesity Strokes Stroke Risk Factors

Drug regulation – How does it work?

Dr. Malcolm Kendrick

DECEMBER 31, 2022

That rate hovered steady in 2009 and 2010, and then rose to about 70% in 2011, 2012, and 2013. This is a cholesterol lowering injectable drug, known as a PCSK9-Inhibitor. They all lower cholesterol (LDL) more than statins – hooray (or perhaps not). Cholesterol lowering is what the NHS now does. This year’s approval rate?

Cholesterol

Cholesterol POTS Academic Document

What is corruption – and why does it matter so much?

Dr. Malcolm Kendrick

JANUARY 12, 2023

Try publishing a paper suggesting that cholesterol lowering is a waste of time, when the market for cholesterol lowering drugs is worth hundreds of billions. If research is directed almost entirely towards ideas that support commercial goals, then this will end up crushing work that dares look in different directions.

Research

Research Cancer Innovation Academic

Post Pandemic, US Cardiovascular Death Rate Continues Upward Trajectory

DAIC

JANUARY 25, 2024

Investigators from the US Centers for Disease Control and Prevention (CDC) and Northwestern University Feinberg School of Medicine analyzed information from more than 10 million death certificates of US adults (aged 35+ years) whose deaths occurred between 2010 and 2022. from 2010 to 2019.

COVID-19

COVID-19 Public Health Heart Disease Chronic Disease

Can a Medical Record Predict Cardiac Arrest Risk?

DAIC

JUNE 14, 2024

Getty Images milla1cf Fri, 06/14/2024 - 19:30 June 14, 2024 — Until now, known risk factors for cardiac arrest have been limited to cardiovascular conditions such as hypertension and high cholesterol. million patients who sought care between 2010 and 2021 at UW Medicine, a large academic healthcare system in Seattle.

Cardiac Arrest

Cardiac Arrest Public Health Risk Factors Research

Menopause, HRT & Cardiovascular Risk

Dr. Paddy Barrett

OCTOBER 17, 2023

Cholesterol & Menopause Familial hyperlipidemia (FH) is a genetic cholesterol disorder which impacts about 1:200 people. Males tend to have higher LDL cholesterol concentrations earlier in life which is one of the key reasons they develop cardiovascular disease earlier in life.

Cholesterol

Cholesterol Cardiovascular Disease Heart attacks Heart Attack

National Trends of Vascular Risk Factor Control Among Stroke Survivors: From the National Health and Nutrition Examination Survey 2009 to 2020

Journal of the American Heart Association

MARCH 8, 2024

BackgroundContemporary data describing the national trends on vascular risk factor control among stroke survivors are limited.Methods and ResultsThis is a cross‐sectional analysis of the National Health and Nutrition Examination Survey cycles 2009 to 2010 to 2017 to March 2020. in 2009–2010 versus 61.5% in 2009–2010 versus 38.6%

Risk Factors

Risk Factors Strokes Stroke Blood Pressure

Long-Term Mortality in Patients With Severe Hypercholesterolemia Phenotype From a Racial and Ethnically Diverse US Cohort

Circulation

NOVEMBER 16, 2023

BACKGROUND:Tools for mortality prediction in patients with the severe hypercholesterolemia phenotype (low-density lipoprotein cholesterol ≥190 mg/dL) are limited and restricted to specific racial and ethnic cohorts. Patients <18 years of age or with previous malignancy were excluded. The primary end point was all-cause mortality.

Cholesterol

Cholesterol Myocardial Infarction Kidney Disease Heart Failure

Longitudinal Assessment of Subclinical Arterial Inflammation in Patients Receiving Immune Checkpoint Inhibitors by Sequential [18F]FDG PET Scans

Circulation: Cardiovascular Imaging

FEBRUARY 4, 2025

Cross-sectional analyses suggested a negative effect of cholesterol-lowering medication on arterial [18F]FDG uptake at follow-up. Patients aged 65 years with at least 4 sequential scans within 30 months were included. In a time-dependent interaction analysis, arterial [18F]FDG uptake increased by 0.8%

Cancer

Cancer Atherosclerosis Cardiovascular Imaging Cholesterol

The legal case – naming a few names

Dr. Malcolm Kendrick

OCTOBER 30, 2024

I, Dr Malcolm Kendrick, with or without other co-conspirators, would be accused of spreading misinformation about cholesterol and statins. The hypothesis that a raised cholesterol level causes heart disease [atherosclerotic cardiovascular disease (ASCVD)] is possibly the single most powerful idea in medicine. With thousands dying.

Cholesterol

Cholesterol Article Research Diet

Association of cumulative non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with the risk of cardiometabolic disease

Cardiovascular Disease and Deaths On the Rise

Heterogeneity in the Prevalence of Cardiovascular Risk Factors by Ethnicity and Birthplace Among Asian Subgroups: Evidence From the 2010 to 2018 National Health Interview Survey

Webinars

APOE4 & Cardiovascular Risk

Abstract 258: Comorbidities Associated with Exclusion from rtPA in Obese Ischemic Stroke Patients with History of Smoking

Drug regulation – How does it work?

What is corruption – and why does it matter so much?

Post Pandemic, US Cardiovascular Death Rate Continues Upward Trajectory

Can a Medical Record Predict Cardiac Arrest Risk?

Menopause, HRT & Cardiovascular Risk

National Trends of Vascular Risk Factor Control Among Stroke Survivors: From the National Health and Nutrition Examination Survey 2009 to 2020

Long-Term Mortality in Patients With Severe Hypercholesterolemia Phenotype From a Racial and Ethnically Diverse US Cohort

Longitudinal Assessment of Subclinical Arterial Inflammation in Patients Receiving Immune Checkpoint Inhibitors by Sequential [18F]FDG PET Scans

The legal case – naming a few names

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