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Abstract WMP32: Cross-Platform Proteomics and Machine Learning Algorithms Nominate Biomarkers of Stroke Diagnosis: An Exploratory Study

Stroke Journal

We conducted internal validation on the same samples using the PeptiQuant Plus biomarker assessment kits (BAK-270) for targeted protein quantitation (Figure 1).Results:We Blood samples were collected at admission to the ER before any therapeutic intervention. Results:We included 100 patients (mean age 58.6

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Abstract 146: Data Independent Acquisition Mass Spectrometry Identifies Novel Plasma Protein Biomarkers that Distinguish Transient Ischemic Attack from Stroke Mimics

Stroke Journal

Conclusions:Our discovery proteomics study highlights the potential of DIA-MS proteomics as a valuable tool for discovering novel protein biomarkers to distinguish TIA from MIM. While TIA patients are at an increased risk of stroke, MIM do not need stroke-related management. These findings warrant validation in larger, longitudinal studies.

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Why Walking Might Save Your Life.

Dr. Paddy Barrett

Medicine & Science in Sports & Exercise 42(10):p 1819-1825, October 2010. 2 [link] 3 Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers. Subscribe now 1 Pedometer-Measured Physical Activity and Health Behaviors in U.S. Am J Hum Biol. 2017 Mar;29(2). 4 Trends over 5 decades in U.S.

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Abstract DP16: Plasma Proteomics and Machine Learning Algorithms Nominate Proteins Indicative of Stroke Severity in Acute Ischemic Stroke

Stroke Journal

Conclusions:Our study revealed distinct panels of protein biomarkers capable of classifying AIS patients into NIHSS-defined severity subgroups with high accuracy, particularly for mild, severe, and critical categories. Stroke, Volume 56, Issue Suppl_1 , Page ADP16-ADP16, February 1, 2025. to classify mild NIHSS, 0.66

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Abstract 131: Association Between Left Ventricular Injury Detected by Cardiac MRI and Incident Ischemic Stroke: The Multi-Ethnic Study of Atherosclerosis

Stroke Journal

Background:The association between left ventricular injury (LVI) detected by cardiac magnetic resonance imaging (CMR) and the risk of a subsequent ischemic stroke is unknown.Methods:We studied stroke-free participants in the Multi-Ethnic Study of Atherosclerosis study who underwent a steady-state free precession CMR at Exam 5 (2010-2012).

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APOE4 & Cardiovascular Risk

Dr. Paddy Barrett

2010 Aug 5;3:53-64. Identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology. Sci Transl Med. 2021 Mar 3;13(583):eaaz4564. doi: 10.1126/scitranslmed.aaz4564. 4 De Castro-Orós I, Pocoví M, Civeira F. The genetic basis of familial hypercholesterolemia: inheritance, linkage, and mutations.

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Temporal trends in concordance between ICD-coded and cardiac biomarker-classified hospitalisation rates for acute coronary syndromes: a linked hospital and biomarker data study

Open Heart

Using person-linked hospitalisation data, we compared International Classification of Diseases (ICD)-coded data with biomarker-classified admission rates for ST-segment elevation MI (STEMI), non-STEMI (NSTEMI) and unstable angina (UA) in Western Australia (WA). Results There were 37 272 ACS admissions in 30 683 patients (64.2%