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Type 2 Diabetes Diagnoses Emerge in Teens Months After COVID

Med Page Today

(MedPage Today) -- Children and teens had an increased risk of being diagnosed with type 2 diabetes after COVID-19 infection, a retrospective cohort study of over 600,000 youth suggested. Adolescents 10 to 19 years old had a 55% higher risk for.

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Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals a dynamic multilayered tissue architecture

Journal of Clinical Investigation - Cardiology

Tissue regeneration is orchestrated by macrophages that clear damaged cells and promote regenerative inflammation. How macrophages spatially adapt and diversify their functions to support the architectural requirements of actively regenerating tissue remains unknown. In this study, we reconstructed the dynamic trajectories of myeloid cells isolated from acutely injured and early stage dystrophic muscles.

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ECG Blog #451 — Premature Closure.

Ken Grauer, MD

I was sent the ECG shown in Figure-1 — told only that the patient was a middle-aged man with septicemia. QUESTIONS: Is this rhythm too fast to be sinus tachycardia? Are flutter waves hidden within the QRS and T waves? Are we seeing the retrograde P waves of AVNRT? Is this ATach ( A trial T achycardia )? Figure-1: The initial ECG in today's case. MY Thoughts on Today’s CASE: In my opinion — none of the above answers are optimal to describe the rhythm in Figure-1.

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COVID-19 infection appeared to increase risk of heart attack & stroke up to 3 years later

American Heart News - Heart News

Research Highlights: An analysis of UK Biobank health data that included adults who had mild to severe COVID-19 before vaccines were available found an increased risk of heart attack, stroke and death among those adults during the nearly three-year.

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History of COVID-19 found to double long-term risk of heart attack, stroke and death

Medical Xpress - Cardiology

A history of COVID-19 can double the risk of heart attack, stroke or death according to new research led by Cleveland Clinic and the University of Southern California.

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First Melanoma History is Risk Factor for Subsequent Diagnoses Regardless of Race

HCPLive

This analysis indicates that patients with a history of a first melanoma are at risk for subsequent development of melanoma regardless of their race or their ethnicity.

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Heart failure, atrial fibrillation & coronary heart disease linked to cognitive impairment

American Heart News - Heart News

Statement Highlights: Previous studies have found that 14-81% of patients with heart failure experience some degree of cognitive impairment affecting language, memory or executive function. Evidence also indicates that people with atrial fibrillation.

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Loneliness Tied to Alzheimer's and Dementia Risk

Med Page Today

(MedPage Today) -- Loneliness increased the risk for all-cause dementia, a meta-analysis that included more than 600,000 people showed. Feeling lonely was tied to a 31% higher risk of overall dementia (HR 1.306, 95% CI 1.197-1.426), according.

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Nanoscope Signals BLA Submission for MCO-010 for Retinitis Pigmentosa

HCPLive

Based on the regulatory feedback provided by the FDA, Nanoscope announced plans to initiate Biologics License Application submission in Q1 2025.

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How terrible can it be to fail to recognize OMI? To whom is OMI Obvious or Not Obvious?

Dr. Smith's ECG Blog

This was sent to me by a reader who wishes to remain anonymous. A lady in her 60s came to the ER with chest discomfort and shortness of breath. She had a history of previous anterior MI treated by primary PCI to the proximal LAD. The first EKG is from 2:30 PM on the day of presentation to the ER. Smith : To me this is a blatantly obvious acute anterior OMI.

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COVID-19 infection appeared to increase risk of heart attack and stroke up to 3 years later

Science Daily - Heart Disease

An analysis of data in the UK Biobank has found that COVID-19 infection may increase the risk of heart attack, stroke and death from any cause for up to three years for people with and without cardiovascular disease, according to new research.

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Researchers succeed in creating two interconnected vascular networks

Medical Xpress - Cardiology

Researchers from the Faculty of Medicine and Health Technology (MET) at Tampere University have successfully created a cell culture platform that allows two cultivated vascular networks to interconnect. The blood vessels in these networks are equivalent to human capillaries in size and structure, facilitating the study of human capillary networks in a laboratory setting.

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Certain Arm Positions Can Lead to Inaccurate Blood Pressure Readings

Med Page Today

(MedPage Today) -- Certain arm positions -- supported on a lap or hanging by the side of the body -- led to significant overestimation of blood pressure readings compared with standardized positioning, a randomized trial in JAMA Internal Medicine.

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Short-Term Surge in Air Pollution May Trigger Schizophrenia Episodes

HCPLive

A short-term rise in air pollution levels between neighboring days was significantly linked to an increased risk of schizophrenia hospitalizations in China.

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If you were this patient, would you prefer to be managed with the Queen of Hearts?

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his early sixties with no significant medical history (including a "negative cardiac workup a few years ago" for unclear indication) called 911 for acute chest pain constantly for the past 5 hours. EMS arrived and recorded vital signs within normal limits and the following ECG during active pain: EMS1 @ 0157: What do you think?

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The heart health, dementia link: 7 things to know

Becker's Hospital Review - Cardiology

Addressing heart health earlier in life may affect and even deter dementia risk later in life, according to research published by The American Heart Association Oct. 10 in Stroke.

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Do patients have a “happiness set point?”

Heart Sisters

The best predictor of how happy you'll be several months after a major life event (positive or negative) might be how happy you were before it happened.

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Checkpoint Inhibitors for Lung Cancer Linked to Pulmonary Embolism

Med Page Today

(MedPage Today) -- BOSTON -- Patients with metastatic lung cancer who were treated with immune checkpoint inhibitors (ICIs) had higher odds of developing a pulmonary embolism, according to a retrospective cohort study. Among propensity-matched.

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Jonathan Meyer, MD: Cognitive Gains, Dopamine-Free Schizophrenia Treatment with Xanomeline Trospium Chloride

HCPLive

Xanomeline trospium chloride offers a new pathway in schizophrenia treatment, improving cognitive symptoms without D2 receptor-related side effects like tardive dyskinesia.

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An elderly male with acute altered mental status and huge ST Elevation

Dr. Smith's ECG Blog

Written by Bobby Nicholson What do you think of this “STEMI”? A man in his 90s with a history of HTN, CKD, COPD, and OSA presented to the emergency department after being found unresponsive at home. With EMS, patient had a GCS of 3 and was saturating 60% on room air. He improved to 100% with the addition of non-rebreather, however remained altered and was intubated by EMS with ketamine and succinylcholine.

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Hospitals with highest, lowest 30-day mortality rates for heart attack patients

Becker's Hospital Review - Cardiology

New York City-based NYU Langone hospital had the lowest 30-day mortality rate for heart attack patients in the U.S. between July 1, 2020 and June 30, 2023, according to CMS data released July 31.

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Having a sweet tooth is linked to higher risk of depression, diabetes, and stroke, study finds

Science Daily - Heart Disease

People with a preference for sweets are at a higher risk of developing depression, diabetes, and suffering a stroke, according to new research.

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Highest Paid Medical Specialties in 2024

Med Page Today

(MedPage Today) -- While it's true that becoming a doctor means a guaranteed six-figure salary, these salaries vary dramatically between specialties. The good news is in 2024, the Physician Compensation Report from Doximity listed 12 medical.

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FASCINATE-2: Denifanstat Improves Disease Activity, MASH Resolution, Fibrosis

HCPLive

New phase 2b data highlight denifanstat’s impact on histological features of MASH, meeting both fibrosis improvement and MASH resolution primary endpoints.

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Cath Lab occupied. Which patient should go now (or does only one need it? Or neither?)

Dr. Smith's ECG Blog

This was sent to me by an undergraduate name Hans Helseth, who is an EKG tech, but who is an expert OMI ECG reader. He wrote most of it and I (Smith) edited. A prehospital “STEMI” activation was called on a 75 year old male ( Patient 1 ) with a history of hyperlipidemia and LAD and Cx OMI with stent placement. He arrived to the ED by helicopter at 1507, about three hours after the start of his chest pain while chopping wood around noon.

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McLaren Health forms new Heart & Vascular Institute, taps chief medical director

Becker's Hospital Review - Cardiology

Grand Blanc, Mich.-based McLaren Health Care has established the new McLaren Heart & Vascular Institute, unifying cardiology, vascular and cardiothoracic services across 13 of the health system's Michigan hospitals.

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La insuficiencia cardíaca, la fibrilación auricular y la enfermedad coronaria están relacionadas con el deterioro cognitivo

American Heart News - Heart News

Aspectos destacados de la declaración: En estudios anteriores se ha descubierto que entre el 14 y el 81% de los pacientes con insuficiencia cardíaca presentan algún grado de deterioro cognitivo que afecta el lenguaje, la memoria o la función.

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One Way to Spot Early Cognitive Decline? Medicare Wellness Visits

Med Page Today

(MedPage Today) -- A Medicare annual wellness visit (AWV) was associated with greater recognition of mild cognitive impairment in older adults, a population-based cohort study in Texas showed. Compared with those who didn't have an annual visit.

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CGRP Monoclonal Antibodies Not More Effective Than Topiramate or Botox for Treating Migraine

HCPLive

A study finds CGRP monoclonal antibodies are not clinically superior to topiramate or Botox in treating chronic migraines, raising cost-effectiveness concerns.

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Research advances infusion designed to clean arteries

Science Daily - Heart Disease

Inflammation of the arteries is a primary precursor and driver of cardiovascular disease -- the No. 1 killer of people in the United States. This inflammation is associated with the buildup of dangerous plaque inside the arteries. Advanced treatments are needed to target this inflammation in patients. Researchers have tested a new nanoparticle nanotherapy infusion that precisely targets inflammation and activates the immune system to help clear out arterial plaque.

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1st COVID wave infections tied to stroke, heart attack risks

Becker's Hospital Review - Cardiology

People who had a confirmed case of COVID-19 during the pandemic's first wave have twice the risk of heart attack, stroke and death compared to those who were never infected, according to research funded by the National Institutes of Health.

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Cardiac Contributions to Brain Health: A Scientific Statement From the American Heart Association

Stroke Journal

Stroke, Ahead of Print. The burden of neurologic diseases, including stroke and dementia, is expected to grow substantially in the coming decades. Thus, achieving optimal brain health has been identified as a public health priority and a major challenge. Cardiovascular diseases are the leading cause of death and disability in the United States and around the world.

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Cardiac Surgery-Associated AKI Lower With Extracorporeal Blood Purification

Med Page Today

(MedPage Today) -- A nonselective extracorporeal blood purification (EBP) device connected to the cardiopulmonary bypass circuit during surgery reduced the risk of cardiac surgery-associated acute kidney injury (CSA-AKI), a randomized trial found.

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Age at Onset Predicts Longevity in Long-Term Care of Schizophrenia

HCPLive

Factors, including older age at onset and longer length of stay, may predict longevity for schizophrenia in psychiatric long-term care settings.

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New strategy for cardiac MRI could aid in complex tachycardia treatment

Medical Xpress - Cardiology

A multicenter study has described and validated a new strategy for guiding ablation procedures in patients with complex tachycardias. Ablation procedures use energy—usually heat or cold—to eliminate small areas of heart tissue that cause pathological cardiac arrhythmias, thereby restoring normal heart rhythm. This type of procedure is frequently used to treat ventricular tachycardias originating in areas affected by scarring after a myocardial infarction.

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Early Treatment of Atrial Fibrillation for Stroke Prevention Trial

American College of Cardiology

The goal of the EAST-AFNET 4 trial was to compare a rhythm-control strategy vs. usual care (rate control in the majority of cases) among patients with a recent diagnosis of atrial fibrillation (AF).

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Heart failure, atrial fibrillation and coronary heart disease linked to cognitive impairment

Science Daily - Heart Disease

A new American Heart Association scientific statement suggests addressing cardiovascular health earlier in life may reduce the risk of stroke and help preserve thinking and memory later in life.