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Fitness Level May Offset Genetic Dementia Risk

Med Page Today

(MedPage Today) -- Genetic risk for Alzheimer's disease and dementia appeared to be partly offset by high levels of cardiorespiratory fitness, U.K. Biobank data suggested. Overall, high cardiorespiratory fitness was associated with better global.

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ECG Blog #456 ā€” Acute MI or Something Else?

Ken Grauer, MD

Today's case was contributed by Dr. Magnus Nossen ( from Fredrikstad, Norway ). Dr. Nossen was at his computer ā€” reviewing ECGs from patients recently admitted to his group's hospital service. He came across the ECG shown in Figure-1 ā€” obtained from a woman in her 70s who was admitted to the hospital for new CP ( C hest P ain ). QUESTION: How would YOU interpret the ECG in Figure-1 ?

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Primary care professionals key to helping people achieve & maintain heart health

American Heart News - Heart News

Statement Highlights: A new scientific statement outlines the role of primary care professionals in helping their patients achieve Life's Essential 8, the key measures for improving and maintaining cardiovascular health defined by the American Heart.

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Cholesterol may not be the only lipid involved in trans fat-driven cardiovascular disease

Medical Xpress - Cardiology

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this attention to cholesterol has prompted the development of cholesterol-lowering drugs called statins and lifestyle interventions like dietary and exercise regimens.

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Prehospital Cath Lab Activation. What happened when the medics and patient arrived at this Academic ED?

Dr. Smith's ECG Blog

This was texted to me by a paramedic while I was out running one day: "54 yo male chest pain started at 1pm. History of diabetes type II and stent placement in 2018. Iā€™m seeing hyperacute T waves III, aVF, down sloping depression I and aVL. Thoughts?" What do you think? I responded: "Definite inferior OMI. And Right Ventricular. Activated the Cath Lab.

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Mapping the intersection of sudden cardiac death and COVID-19: a comprehensive bibliometric analysis (2020ā€“2024)

Frontiers in Cardiovascular Medicine

IntroductionA direct causal link between Sudden Cardiac Death (SCD) and COVID-19 is unproven, although current data suggest a plausible association.AimThis study aims to map and analyze the intersection of research on sudden cardiac death and COVID-19 through a comprehensive bibliometric analysis.MethodologyThis study searched the literature by applying the keywords ā€œCOVID-19ā€ AND ā€œSudden Cardiac Death (SCD)ā€.

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In a small international trial, novel oral medication muvalaplin lowered Lp(a)

American Heart News - Heart News

Research Highlights: The oral medication muvalaplin may safely lower high levels of lipoprotein(a), also known as Lp(a), an independent, inherited risk factor for cardiovascular disease. Muvalaplin is a small molecule inhibitor that prevents the.

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IL-18 Levels Associated With Long COVID Risk in People With Rheumatic Diseases

HCPLive

IL-18 levels were consistently lower across participants with different SARDs, remission status, and COVID-19 disease characteristics.

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Protein in soy may reduce the risk of heart failure by affecting gut bacteria

Medical Xpress - Cardiology

A research team from the Nagoya University Graduate School of Medicine has discovered a promising way to slow the progression of heart failure in mice. They fed mice a diet rich in the soybean protein, Ī²-conglycinin (Ī²-CG), which can support heart health by influencing gut bacteria. Their analysis revealed that the soybean protein rich diet increased the production of the short-chain fatty acids (SCFAs) in the intestine that play a role in protecting the heart.

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Lactate reprograms glioblastoma immunity through CBX3-regulated histone lactylation

Journal of Clinical Investigation - Cardiology

Glioblastoma (GBM), an aggressive brain malignancy with a cellular hierarchy dominated by GBM stem cells (GSCs), evades antitumor immunity through mechanisms that remain incompletely understood. Like most cancers, GBMs undergo metabolic reprogramming toward glycolysis to generate lactate. Here, we show that lactate production by patient-derived GSCs and microglia/macrophages induces tumor cell epigenetic reprogramming through histone lactylation, an activating modification that leads to immunosu

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Tirzepatide lowered risk of worsening heart failure and CVD death for obese adults

American Heart News - Heart News

Research Highlights: In an international trial of 713 adults in nine countries including the U.S. called SUMMIT, participants with heart failure with preserved ejection fraction (HFpEF) and obesity taking tirzepatide for an average of 2 years had.

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Reused Pacemakers Good as New in Early Safety Data

Med Page Today

(MedPage Today) -- CHICAGO -- Secondhand permanent pacemaker use in poorer countries, following thorough cleaning and repackaging, has not resulted in patient harm so far, according to the My Heart Your Heart trialists. In patients who could.

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Obesity-Related Heart Disease Deaths Rose Roughly 180% Since 1999

HCPLive

Obesity-related ischemic heart disease deaths rose from 1999 to 2020, particularly in middle-aged men and Black adults, per CDC WONDER data.

Obesity 111
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Sitting too long can harm heart health, even for active people

Science Daily - Heart Disease

More time spent sitting, reclining or lying down during the day may increase the risk of cardiovascular disease (CVD) and death, according to a new study. More than roughly 10-and-a-half hours of sedentary behavior per day was significantly linked with future heart failure (HF) and cardiovascular (CV) death, even among people meeting recommended levels of exercise.

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A Motherā€™s Battle with Lung Cancer and the Importance of Early Detection

CTVS

This Thanksgiving, 39-year-old Cherith Satterfield has much to be grateful for as she gathers with her family. The wife, mother of five, three grown and two at home, was unexpectedly diagnosed with a rare, aggressive form of lung cancer earlier this year. For Cherith, the journey has been a powerful reminder to take your health seriously.

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Spironolactone, a blood pressure medication, may help reduce risk of new heart failure

American Heart News - Heart News

Research Highlights: The CLEAR SYNERGY trial found that spironolactone may reduce the risk of new or worsening heart failure; however, it did not significantly impact the rate of death, new heart attack or stroke. More research is needed to further.

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Tirzepatide Officially Puts GLP-1 Meds on the Map for Obesity-Related Heart Failure

Med Page Today

(MedPage Today) -- CHICAGO -- A long-acting GIP/GLP-1 receptor agonist conferred significant clinical benefit for people with obesity and accompanying heart failure with preserved ejection fraction (HFpEF), according to the SUMMIT trial. Incident.

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Barry A. Borlaug, MD: Impact of Tirzepatide on Cardiorenal End-Organ Damage in HFpEF

HCPLive

Barry A. Borlaug, MD describes the beneficial effect of tirzepatide on circulatory pressure-volume overload and end-organ damage in patients with HFpEF and obesity.

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Hospitals with highest, lowest readmission rates for coronary bypass

Becker's Hospital Review - Cardiology

Tyler, Texas-based Christus Mother Frances Hospital had the lowest unplanned readmission rate for coronary artery bypass graft surgery in the U.S. between July 1, 2020, and July 30, 2023, according to CMS data released Oct. 30.

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5 Most-Cited Takeaways From the 19th Annual Cardiometabolic Health Congress (CMHC)Ā 

Cardiometabolic Health Congress

With the holiday season approaching and fall in full swing, it’s the perfect time to reaffirm our commitment to delivering excellent care, improving patient outcomes, and making the most of every available resource. What better way to join the fall festivities than by spotlighting key insights in cardiorenal metabolic medicine, primary prevention, and quality of life improvements shared at this year’s biggest U.S. cardiometabolic health CME/CE conference: the 19th Annual CMHC.

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Ablation may be better than medication for those with dangerous heartbeat after heart attack

American Heart News - Heart News

Research Highlights: A new, multicenter study demonstrated that ablation treatment may be a better first option than medication for many heart attack survivors who develop abnormal electrical short circuits in their heart, which are episodes of.

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Stroke Risk Is Changing With the Climate

Med Page Today

(MedPage Today) -- The world endured its hottest summer on record in 2024, and the transition to fall brought devastation from multiple hurricanes in the U.S. The growing effects of climate change are widespread and becoming more severe. Now, new.

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Oussama Wazni, MD, MBA: OPTION Trial and the Role of LAAC in Atrial Fibrillation

HCPLive

Oussama Wazni, MD, discusses the results of the OPTION trial examining LAAC in atrial fibrillation as well as its reception as AHA 2024.

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Charting the future of cardiology with large language model artificial intelligence

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 19 November 2024; doi:10.1038/s41569-024-01105-y Large language models represent a transformative leap in artificial intelligence and natural language processing, offering exciting potential across cardiology, from clinical care to education and research. However, several crucial challenges limit the practical implementation of large language models in cardiology.

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Genetic study links heart shape to cardiovascular disease

Medical Xpress - Cardiology

A new, multinational study has revealed that the shape of the human heart, influenced by genetic factors, could serve as a valuable predictor for cardiovascular disease risk.

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Los profesionales de atenciĆ³n primaria, clave para ayudar a las personas a lograr y mantener la salud cardĆ­aca

American Heart News - Heart News

Aspectos destacados de la declaraciĆ³n: Una nueva declaraciĆ³n cientĆ­fica describe el papel de los profesionales de atenciĆ³n primaria en la ayuda a sus pacientes para lograr Los Ocho Pases Esenciales Para Mi Salud, las medidas clave para mejorar y.

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GLP-1 Drugs Could Help People With Alcohol Use Disorder

Med Page Today

(MedPage Today) -- Some GLP-1 receptor agonists may hold promise as treatments for alcohol use disorder (AUD), a Swedish observational study suggested. Among more than 200,000 individuals with AUD, those taking semaglutide (Ozempic, Wegovy) had.

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Kara Margolis, MD: Long-Term Impact of Maternal Microbiota on Infant Gut-Brain Health

HCPLive

At NASPGHAN, HCPLive spoke with Margolis about her teamā€™s study on the link between maternal SSRI exposure and an infantā€™s development of gut-brain interaction disorders.

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How You Can Reduce The Risk Of Heart Disease Without Losing Weight.

Dr. Paddy Barrett

Being overweight is a major risk factor for heart disease and also an early death. But even if you have excess weight, there are many things you can do to seriously reduce that risk without focusing on weight loss itself. So, if you struggle with excess weight, you need to know what else you can do to reduce your future risk. The Life Essential 8 are a set of factors that significantly influence your risk of heart disease and early death, including: Regular Physical Activity.

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Study reveals COVID-19 vaccine safety in patients with atrial fibrillation/flutter

Medical Xpress - Cardiology

Development of the coronavirus disease 2019 (COVID-19) vaccine has been key to countering the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite the current endemic status of COVID-19, patients with comorbidities and older adults remain vulnerable to severe illness and death due to COVID-19 infection. Therefore, medical agencies and organizations worldwide recommend COVID-19 vaccination, especially for individuals with an underlying disease.

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Email reminders improved flu shot rates in Denmark, notably among heart attack survivors

American Heart News - Heart News

Research Highlights: An electronic message to "nudge" patients to get a flu vaccine highlighting the cardiovascular benefits of flu shots improved vaccination rates among more than two million adults in three clinical trials in Denmark. The research.

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Opioids Tied to Higher Dementia Risk, but Only After a Point

Med Page Today

(MedPage Today) -- After a certain threshold, cumulative opioid use was associated with higher dementia risk, a study of adults over age 60 in Denmark showed. In a nested case-control study, opioid use above 90 total standardized doses (TSDs.

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Intensive Blood Pressure Regimen Lowers CVD Risk in People with T2D

HCPLive

Reducing systolic blood pressure to less than 120 mmHg lowered the risk of major cardiovascular events for most people with diabetes in the BPROAD trial.

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Breaking every hour of sedentary time with 10 mins of light exercise significantly reduced blood pressure

Science Daily - Heart Disease

Time spent sedentary beyond six hours per day during growth from childhood through young adulthood may cause an excess increase of 4 mmHg in systolic blood pressure, a new study shows. Continuously engaging in light physical activity (LPA) significantly mitigated the rise in blood pressure.

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180% increase in obesity-related heart disease deaths: 8 notes

Becker's Hospital Review - Cardiology

Between 1999 and 2020, obesity-related deaths from heart disease deaths in the U.S. increased by 180%, according to a preliminary study to be presented at the American Heart Association's annual Scientific Sessions, set for Nov. 16-18.

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Editorial warns of heart disease risks associated with yo-yo dieting

Medical Xpress - Cardiology

A new editorial published in Nature suggests that frequent fluctuations in diet, commonly known as "yo-yo dieting," can significantly increase the risk of cardiovascular disease.

Diet 81
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Small Benefit, Persistent Toxic Risk With Adjuvant Anthracycline in Breast Cancer

Med Page Today

(MedPage Today) -- Adding an anthracycline to adjuvant chemotherapy for TOP2A-normal early breast cancer significantly improved disease-free survival (DFS) but not overall survival (OS) at 10 years, and doubled the risk of heart failure, a randomized.

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