Phosphatidylethanol Aids Detection of Alcohol Relapse Post-Liver Transplant
HCPLive
NOVEMBER 5, 2024
Alcohol relapses were detected more frequently after the introduction of phosphatidylethanol in orthotopic liver transplant recipients.
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Defibrillation devices can save lives using 1,000 times less electricity
Science Daily - Heart Disease
NOVEMBER 5, 2024
Researchers used an electrophysiological computer model of the heart's electrical circuits to examine the effect of the applied voltage field in multiple fibrillation-defibrillation scenarios. They discovered far less energy is needed than is currently used in state-of-the-art defibrillation techniques. The authors applied an adjoint optimization method and discovered adjusting the duration and the smooth variation in time of the voltage supplied by defibrillation devices is a more efficient mec
Study: Low-level lead poisoning accounts for cognitive deficits in children, risk factors for heart conditions
Medical Xpress - Cardiology
OCTOBER 30, 2024
Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe, according to a paper by Columbia University Mailman School of Public Health, Simon Fraser University in Canada, and Harvard Medical School, and Boston Children's Hospital.
One Of The Biggest Impact Things You Can Do To Live Longer.
Dr. Paddy Barrett
NOVEMBER 1, 2024
“But what can I do to make a difference?” This is one of the most common questions I get as a cardiologist when talking about preventing heart disease and living longer. As a doctor, there are many things I can do, and only a doctor can do: Prescribe medications Order certain diagnostic tests. Perform or arrange medical procedures. And so on.
Alzheimer's Progression May Be Slowed by Targeted Magnetic Pulses, Study Suggests
Med Page Today
NOVEMBER 3, 2024
(MedPage Today) -- Investigational transcranial magnetic stimulation that targeted a brain network involved in memory slowed progression in mild-to-moderate Alzheimer's disease, data from a small phase II study suggested. At 1 year, noninvasive.
ECG Blog #454 — Look for the "Break".
Ken Grauer, MD
NOVEMBER 1, 2024
I was sent this ECG recording — and asked for my interpretation of the rhythm in Figure-1. I had little clinical information. QUESTIONS: How was I able to guess the probable correct answer in less than 5 seconds? How was I then able to prove that my guess was correct? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ).
Exploring the Interplay Between Chronic Kidney Disease and Cardiovascular Disease
HCPLive
OCTOBER 31, 2024
In this first of this 5-part series, Lerma and Lala-Trindade discuss the interplay between chronic kidney disease and cardiovascular disease.
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Long COVID inflammation damages the heart, study finds
Science Daily - Heart Disease
OCTOBER 31, 2024
New research has found inflammatory markers in the blood of long COVID patients which could explain why many experience ongoing cardiovascular issues.
ASA Advises No Longer Holding GLP-1 Agents Prior to Surgery for Most Patients
Med Page Today
OCTOBER 30, 2024
(MedPage Today) -- Most patients should not stop taking GLP-1 receptor agonists prior to elective surgery, according to updated guidance from several medical societies, including the American Society of Anesthesiologists (ASA). This recommendation.
50 top hospitals for vascular surgery: Healthgrades
Becker's Hospital Review - Cardiology
OCTOBER 30, 2024
Healthgrades published its 2025 Specialty Excellence Awards recipients Oct. 22. Of those recipients, 50 hospitals were recognized for delivering superior clinical outcomes in vascular surgery.
Long COVID inflammation damages the heart, blood analysis finds
Medical Xpress - Cardiology
OCTOBER 31, 2024
University of Queensland-led research has found inflammatory markers in the blood of long COVID patients which could explain why many experience ongoing cardiovascular issues.
Omega-3 Supplements Show Benefit in APOE4 Carriers
Med Page Today
NOVEMBER 1, 2024
(MedPage Today) -- High-dose supplements of docosahexaenoic acid (DHA), an omega-3 fatty acid, penetrated the brain in both APOE4 carriers and non-carriers before dementia onset, the placebo-controlled PreventE4 trial showed. The treatment did.
What's overweight enough for lower disability after stroke?
Science Daily - Stroke
NOVEMBER 5, 2024
Slightly overweight stroke survivors have a lower risk of sustaining disabilities. New research adds another aspect to the obesity paradox but also highlights the importance of considering the population's normal when recommending best practices.
Normothermic Machine Perfusion Shows Promise in High-Acuity Liver Transplants
HCPLive
NOVEMBER 5, 2024
Normothermic machine perfusion in liver transplants improves preservation, reduces early complications, and shows promise in complex cases.
Heart signals brain to boost sleep for healing after heart attack, study finds
Medical Xpress - Cardiology
OCTOBER 30, 2024
A heart attack can trigger a desire to get more sleep, allowing the heart to heal and reduce inflammation—and this happens because the heart sends special signals to the brain, according to a new Mount Sinai study.
Researchers identify 'sweet spot' for safe surgery after heart attack
Science Daily - Heart Disease
OCTOBER 30, 2024
New research suggests older adults wait 3-6 months after a heart attack before elective noncardiac surgery to reduce the risk of serious complications like stroke or another heart attack.
Cardiac Arrest Drug Administration Route a Toss Up
Med Page Today
OCTOBER 31, 2024
(MedPage Today) -- Intraosseous vascular access for the administration of epinephrine during out-of-hospital cardiac arrest wasn't better than going for the veins first, two separate randomized trials showed. In the PARAMEDIC-3 trial conducted.
Chest pain and Saddleback STE. For Which of these 6 Cases should we Activate the cath lab? And how does the Queen of Hearts perform?
Dr. Smith's ECG Blog
OCTOBER 30, 2024
Smith Introduction: Saddleback ST Elevation is often an OMI mimic, so one needs to scrutinize these ECGs!! Written by Magnus Nossen Below are ECGs from six different patients. All of the patients contacted EMS due to acute onset chest pain. Imagine you get these ECGs in real time and you are asked whether or not the cath lab should be activated? All ECGs in this case have saddleback ST elevation.
Stress Triggers IBS Symptoms, Impacts Quality of Life More Than Diet, Study Finds
HCPLive
OCTOBER 31, 2024
Mohammad Abuassi, MD, explains how classifying IBS based on triggers can aid the development of effective, personalized approaches to management.
Atrial appendage closure is associated with increased risk for postoperative atrial fibrillation
Journal of Cardiothoracic Surgery
NOVEMBER 1, 2024
This study aims to examine the relationship between left atrial appendage closure (LAAC) and post-operative atrial fibrillation (POAF) in cardiac surgery patients with no pre-operative atrial fibrillation (AF).
Low-level lead poisoning is still pervasive in the US and globally
Science Daily - Heart Disease
OCTOBER 30, 2024
Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe, Low-level lead poisoning is a risk factor for preterm. Annually 5.5 million deaths from cardiovascular disease attributed to low-level lead poisoning; accounts for a loss of 765 million IQ points in children.
Weight Loss After Bariatric Surgery in Teens Persisted at 10 Years
Med Page Today
OCTOBER 30, 2024
(MedPage Today) -- For adolescents, weight loss after bariatric surgery was durable out to 10 years, data from the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study confirmed. Among 260 adolescents who underwent bariatric surgery.
Study shows no difference between two common methods for saving lives during cardiac arrest
Medical Xpress - Cardiology
OCTOBER 31, 2024
There is no difference in the effectiveness of the two most commonly used methods for administering medication during out-of-hospital cardiac arrest.
ESSENCE: Semaglutide Improves Fibrosis, Resolves Steatohepatitis in MASH
HCPLive
NOVEMBER 1, 2024
Headline results from part 1 of the phase 3 ESSENCE trial highlight semaglutide 2.4 mg’s benefits for fibrosis and steatohepatitis in patients with MASH.
Brighter nights and darker days could lead to an early grave
Science Daily - Stroke
OCTOBER 31, 2024
A study of more than 13 million hours of data, collected from light sensors worn by 89,000 people, has found exposure to bright nights and dark days is associated with an increased risk of death.
Can you treat Non-STEMI with thrombolytics if it is OMI (Occlusion MI)? Of course!
Dr. Smith's ECG Blog
OCTOBER 31, 2024
This case was sent by an old residency friend, Kirk Lufkin. He works in a small hospital in Northern Michigan. Case A 61 year old female. hypertension no other past history presented with 30 minutes of fluctuating non-radiating heaviness in chest, with diaphoresis and nausea. VS normal. No cardiac past history. Here is her ECG: What do you think? There are inferior hyperacute T-waves (diagnostic of inferior OMI), with 1) reciprocal ST depression in aVL, 2) a reciprocally inverted hyperacute T-wa
Colchicine Goes Belly-Up in a More Definitive Heart Attack Trial
Med Page Today
OCTOBER 30, 2024
(MedPage Today) -- Any cardiovascular protection from colchicine in heart attack survivors seemed to be debunked with a better-powered randomized trial, researchers found. Between acute MI patients randomized to colchicine or placebo right after.
Stroke treatments explained
Medical Xpress - Cardiology
OCTOBER 31, 2024
Each year, an estimated 15 million people around the globe experience stroke, according to the World Health Organization, with one-third resulting in death. That's why immediate stroke treatment is crucial.
Violeta Popov, MD, PhD: Do GLP-1 RAs Need to Be Held Before Endoscopy?
HCPLive
OCTOBER 30, 2024
Popov reviews findings from her late-breaking presentation at ACG 2024 suggesting GLP-1 RAs may not need to be held prior to upper endoscopy.
Targeting aryl hydrocarbon receptor functionally restores tolerogenic dendritic cells derived from patients with multiple sclerosis
Journal of Clinical Investigation - Cardiology
NOVEMBER 1, 2024
Multiple sclerosis (MS) is a chronic disease characterized by dysregulated self-reactive immune responses that damage the neurons’ myelin sheath, leading to progressive disability. The primary therapeutic option, immunosuppressants, inhibits pathogenic anti-myelin responses but depresses the immune system. Antigen-specific monocyte-derived autologous tolerogenic dendritic cells (tolDCs) offer alternative therapeutic approaches to restore tolerance to autoantigens without causing generalized immu
Electrophysiological curiosity. Can you spot it?
Dr. Smith's ECG Blog
NOVEMBER 3, 2024
Written by Magnus Nossen ( with comments and laddergram by Ken Grauer ) The patient in today’s case is a man in his 60s — who presented with palpitations and lightheadedness. He had no history of syncope. The patient had hypertension, but was otherwise healthy. Due to the reported symptoms, he was admitted for observation and put on telemetry monitoring.
TCT 2024’s Top TAVR Studies
CardiacWire
NOVEMBER 3, 2024
This year’s TCT conference saw a deluge of TAVR studies examining everything from the efficacy of valve designs to TAVR’s impact on aortic and tricuspid regurgitation. Out of all these TAVR studies, the four that could have the greatest clinical impact focused on interventional timing and the risk of comorbidities and procedural complications. The EARLY TAVR trial shined the brightest spotlight on TAVR timing, finding that earlier intervention in patients with asymptomatic severe AS may be more
Database analysis identifies 'sweet spot' for safe surgery after heart attack
Medical Xpress - Cardiology
OCTOBER 30, 2024
After a heart attack, aging adults face double or triple the risk of life-threatening complications—like a debilitating stroke or another heart attack—when they move forward with elective noncardiac surgeries too soon, according to new University of Rochester research published in JAMA Surgery.
Current Interventions Fail to Reduce Benzodiazepine Use in Older Adults
HCPLive
NOVEMBER 2, 2024
Neither clinician peer comparison nor patient informational mail reduced benzodiazepine use among older adults in anesthesia care, a new study finds.
Targeting TET3 in macrophages provides a concept strategy for the treatment of endometriosis
Journal of Clinical Investigation - Cardiology
NOVEMBER 1, 2024
Endometriosis, characterized by the presence of endometrial-like tissue outside the uterus, is a condition associated with pain and infertility. In this issue of the JCI, Lv et al. illuminate the critical pathophysiological role of the ten-eleven translocation 3 (TET3) in endometriosis. TET3 expression levels were higher in macrophages of endometriotic lesions compared with control endometrial tissue, implicating TET3 as a contributing factor in the chronic inflammation that occurs in endometrio
The Way to a Patient’s Heart — Vascular Access in Cardiac Arrest
The New England Journal of Medicine
OCTOBER 30, 2024
Every year, thousands of lives are saved with cardiopulmonary resuscitation (CPR). Yet, overall survival among patients with out-of-hospital cardiac arrest is approximately 10%, even in well-performing emergency medical systems. The interventions that are undertaken at the scene of a cardiac arrest are the most likely interventions to improve outcomes: early.
Impact of aortic and pulmonary artery wall histology on radicular dilatation during the Ross procedure
Journal of Cardiothoracic Surgery
OCTOBER 31, 2024
In our study, we aim to explore the structural differences between the aortic root and the pulmonary artery to better understand the process of pulmonary autograft dilatation during the Ross procedure.
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