Low Serum Vitamin D, Zinc Shown to be Risk Factor for Alopecia Areata
HCPLive
JANUARY 14, 2025
These findings suggest that zinc and vitamin D levels may function as a disease severity indicator for patients with alopecia areata.
Trending Articles
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Here's What It Will Take to Grow HIV-Positive to HIV-Positive Transplant Access
Med Page Today
JANUARY 14, 2025
(MedPage Today) -- In late November, HHS issued a final rule updating transplant regulations to enable every U.S. transplant center to transplant kidneys and livers from donors with HIV into recipients with HIV -- this is a milestone to be recognized.
Dementia Cases to Double in the U.S.
Med Page Today
JANUARY 13, 2025
(MedPage Today) -- Dementia cases in the U.S. are expected to double in the next four decades, a new analysis suggested. In a racially and geographically diverse sample, the lifetime risk of dementia was estimated at 42% (95% CI 41-43) with incidence.
Blood pressure trial intervention shows mixed outcomes in chronic kidney disease patients
Medical Xpress - Cardiology
JANUARY 10, 2025
Stanford University School of Medicineled researchers have found that intensive blood pressure (BP) control produces cardiovascular benefits and increases the risk of adverse events in people with chronic kidney disease (CKD).
Study Shows a Correlation Between Social Media Use and Irritability
HCPLive
JANUARY 10, 2025
New research reveals that frequent social media use, especially active use of platforms such as TikTok and Facebook, is linked to greater irritability levels.
Association between triglyceride-glucose (TyG) related indices and cardiovascular diseases and mortality among individuals with metabolic dysfunction-associated steatotic liver disease: a cohort study of UK Biobank
Cardiovascular Diabetology
JANUARY 12, 2025
Triglyceride-glucose (TyG) related indices, which serve as simple markers for insulin resistance, have been closely linked to metabolic dysfunction-associated steatotic liver disease (MASLD), cardiovascular di.
Multi-disciplinary treatment of broncho-esophageal fistula in a high-risk single-lung patient
Journal of Cardiothoracic Surgery
JANUARY 10, 2025
A broncho-esophageal fistula (BEF) is a medical and surgical disaster. Treatment of BEF is often limited to palliative stent treatment that may migrate or cause erosions and tissue necrosis. Surgical repair of.
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Atherosclerosis in diabetes mellitus: novel mechanisms and mechanism-based therapeutic approaches
Nature Reviews - Cardiology
JANUARY 12, 2025
Nature Reviews Cardiology, Published online: 13 January 2025; doi:10.1038/s41569-024-01115-w In this Review, Khan and Jandeleit-Dahm discuss pathological mechanisms involved in atherosclerosis development and progression in patients with diabetes mellitus and highlight novel therapeutic targets to treat atherosclerosis in these patients.
Right ventricles road to recovery: remodelling after chronic thromboembolic pulmonary hypertension intervention
Heart BMJ
JANUARY 13, 2025
Right heart failure is the most common cause of mortality in patients with pulmonary arterial hypertension. 1 This includes chronic thromboembolic pulmonary hypertension (CTEPH), which through obstruction of the pulmonary arteries increases afterload on the right ventricle (RV), ultimately resulting in RV failure. Histopathologically, it is also associated with microvascular changes, with smooth muscle hypertrophy, and intimal fibrosis, which cause stiffening, reduced compliance and increased re
Diabetes Med for Kidney Stones? Exercise and Heart Failure
Med Page Today
JANUARY 11, 2025
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.
High blood pressure in pregnancy a risk factor for early heart disease
Medical Xpress - Cardiology
JANUARY 10, 2025
A study has revealed a significant link between a common pregnancy complication and early heart disease in women. The study is published in the Journal of the American College of Cardiology.
Racial, Ethnic Pediatric Kidney Transplant Disparities Suggest Inequities in ESRD Care
HCPLive
JANUARY 10, 2025
Non-Hispanic Black and Hispanic children were less likely to undergo preemptive KT and had longer wait times than non-Hispanic White children.
Artificial Intelligence–Guided Lung Ultrasound by Nonexperts
JAMA Cardiology
JANUARY 14, 2025
This multicenter validation study evaluates the ability of artificial intelligence to guide acquisition of diagnostic-quality lung ultrasound images by trained health care professionals.
Overcoming the Odds with Expert Fetal Cardiology Care: Zeke and Zane’s Story
Conquering CHD
JANUARY 17, 2025
Zane had three open heart surgeries before he turned 3. And surprisingly, he had a more routine care journey than his brother, Zeke. Zeke and Zane were both diagnosed with hypoplastic left heart syndrome (HLHS) before birth. As far as congenital heart diseases go, HLHS falls on the rarer end of the spectrum. The odds that either boy would have the condition are low roughly 1 in every 3,800 babies are born with it.
SGARBOSSA CRITERIA
ECG Guru
JANUARY 13, 2025
This ECG was sent to me by a friend, I don't know if he did it himself. The question was whether a heart attack can be recognized here. The patient is a 55-year-old man who has typical angina pectoris lasting more than 1 hour. What can you answer?
Implantable cardiac defibrillator shocks vs. “careful and kind” end-of-life care
Heart Sisters
JANUARY 12, 2025
Study: Even among patients with a Do-Not-Resuscitate order, over half had their implanted cardiac defibrillators programmed ON in the final hour of life. How can this be happening?
Critical Gaps in FSGS Treatment Highlight Need for New Therapies, with Pipeline Assets from Travere, Vertex, and Dimerix Poised to Address Unmet Needs
HCPLive
JANUARY 14, 2025
US nephrologists estimate half of all FSGS patients are not optimally managed, according to Spherix Global Insights.
Stroke Mimics at 30 Years: Where We Have Been, Where We Are Now, and Where We Are Going
Stroke Journal
JANUARY 13, 2025
Stroke, Ahead of Print. Stroke mimics and chameleons remain a major challenge to the clinician and clinical investigator. Misdiagnosis of stroke can result in significant harm to our patients, as well as unnecessary financial costs to the health care systems internationally. The approach to stroke mimics and chameleons has evolved over time with the development of clinical scales and technology.
Sacubitril/valsartan versus valsartan initiation in patients naïve to renin–angiotensin system inhibitors: Insights from PARAGLIDE‐HF
European Journal of Heart Failure
JANUARY 10, 2025
Changes in N-terminal pro-B-type natriuretic peptide and assessment of clinical endpoints according to prior exposure to reninangiotensin system inhibitors in the Pre-specified substudy of Prospective comparison of ARNI with ARB Given following stabiLization In DEcompensated HFpEF (PARAGLIDE-HF). ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; CI, confidence interval; CV, cardiovascular; EF, ejection fraction; HF, heart failure.
State-of-the-Art Review Examines LAAO as Therapy For Stroke Prevention in Patients With AFib
American College of Cardiology
JANUARY 14, 2025
he utility of left atrial appendage occlusion (LAAO) as a therapy for stroke prevention in patients with nonvalvular atrial fibrillation (AFib) is the focus of a State-of-the-Art Review published Jan. 8 in JACC: Clinical Electrophysiology.
Experts Pitch Major Overhaul to How Obesity Is Diagnosed
Med Page Today
JANUARY 14, 2025
(MedPage Today) -- Medical experts from around the globe proposed a more nuanced approach to diagnosing obesity that does not rely exclusively on body mass index (BMI) alone. Writing in The Lancet Diabetes & Endocrinology, the global commission.
Emotional Resilience Linked to Better Quality of Life for Those with Acne
HCPLive
JANUARY 15, 2025
This study pointed to the abilities of patients with acne to adapt to stress and adversity as helpful in making skin-related quality of life improvements.
Brain connectome phenotype linked to cerebrovascular disease can track cognitive decline
Science Daily - Stroke
JANUARY 13, 2025
Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer's disease (AD) pathology to impact neurodegeneration and cognition in older adults.
Hip fractures linked to fivefold increase in cardiovascular event risk in patients with heart failure
Medical Xpress - Cardiology
JANUARY 10, 2025
A research team in the Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), found that hip fractures not only result in both physical and psychological injuries, but may also induce adverse cardiovascular events. In particular, hip fracture patients with pre-existing cardiac conditions are associated with a significantly higher risk of cardiovascular events (CVEs) and mortality, poorer prognosis, and greater health service utilization.
Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis
The New England Journal of Medicine
JANUARY 15, 2025
Among patients with asymptomatic severe aortic stenosis, early TAVR was superior to clinical surveillance in reducing the incidence of death, stroke, or unplanned hospitalization for cardiovascular causes.
Transcranial Magnetic Stimulation After Tai Chi Improves Sleep in Older Adults
Med Page Today
JANUARY 10, 2025
(MedPage Today) -- Repetitive transcranial magnetic stimulation (rTMS) added to tai chi chuan exercise improved sleep and cognition in older adults who had both sleep disorders and mild cognitive impairment, a randomized clinical trial showed.
Most Dementia Patients Moved to Nursing Home within 5 Years of Diagnosis
HCPLive
JANUARY 13, 2025
A study found many people with dementia live approximately 1 third of their remaining life expectancy in nursing homes.
A 50-something man with Chest pain at triage
Dr. Smith's ECG Blog
JANUARY 13, 2025
A 50-something male presented to triage with chest pain for one day. An ECG was recorded quickly before any further history or physical exam: What do you think? When I saw this (presented at a conference), I immediately thought it looked like Thype 1 Brugada phenocopy (in other words, Type 1 Brugada ECG pattern ). There is an rSR' in lead V1 without any spike of the R'-wave.
Effective CRISPR modulation of complex non-coding RNA loci
Nature Reviews - Cardiology
JANUARY 13, 2025
Nature Reviews Cardiology, Published online: 14 January 2025; doi:10.1038/s41569-025-01117-2 In this Tools of the Trade article, Francesca Vacante and Andrew Baker describe a CRISPR-based approach to target the regulatory regions of non-coding RNAs.
Link between gene duplications and deletions within chromosome region and nonsyndromic bicuspid aortic valve disease
Science Daily - Heart Disease
JANUARY 15, 2025
Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease.
How Smoking Affects Your Heart and Increases Surgery Risk
MIBHS
JANUARY 15, 2025
Smoking is a well-known health hazard, contributing to a wide array of diseases and conditions. Its effects on the heart are particularly alarming, as smoking significantly increases the risk of cardiovascular diseases (CVDs) and complicates medical procedures such as minimally invasive or bloodless heart surgeries. Understanding how smoking affects the heart and raises surgery risks can empower individuals to make healthier choices and improve outcomes when surgical intervention is necessary.
4D-150 Reduces Injection Burden in DME, Paving Way for FDA-Backed Phase 3
HCPLive
JANUARY 10, 2025
4D-150 shows promising efficacy and safety in DME as FDA greenlights Phase 3 trial for Biologics License Application submission.
CAC Scoring Improves Allocation of Semaglutide, Potentially Mitigates MACE Risk
American College of Cardiology
JANUARY 10, 2025
Among patients without diabetes or cardiovascular disease and with a BMI 27 kg/m2, those with coronary artery calcium (CAC) scoring 300 derive the largest benefit from a weight-loss-dose of semaglutide for the prevention of major adverse cardiovascular events (MACE).
The Finer Points of FINEARTS-HF
CardiacWire
JANUARY 15, 2025
Bayers FINEARTS-HF study revealed that finerenone could be poised to become the next big heart failure treatment at ESC 2024, and a new series of JACC sub-studies just further strengthened its case. FINEARTS-HF explored the effects of finerenone in ~6k HFmrEF/HFpEF patients and found that the drug significantly reduced worsening HF events and CV death versus placebo.
Philips recalls cardiac device software after 2 patient deaths
Becker's Hospital Review - Cardiology
JANUARY 14, 2025
Philips is recalling the software associated with its mobile cardiac outpatient telemetry devices after 109 patient injuries and two patient deaths, a Jan. 13 FDA recall notice said.
What Do We Know About the Pink Flame Retardants Used to Slow the Los Angeles Fires?
Med Page Today
JANUARY 14, 2025
(MedPage Today) -- Aircraft battling fires raging through the Los Angeles area are dropping more than water: Hundreds of thousands of gallons of hot-pink fire suppressant ahead of the flames in a desperate effort to stop them before they destroy.
Virtual Reality Exercise Game Feasible for Patients With Fibromyalgia
HCPLive
JANUARY 15, 2025
A VR exergame may facilitate patients physical activity while promoting relaxation and positive mental states.
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